chirata
swertia chirata herb
Identification
| Name | chirata |
| IUPAC | swertia chirata buch. ham. |
| CAS Number | 977052-80-4 |
| FDA UNII | Search |
| CoE Number | 440 |
Regulatory
| FDA Mainterm (SATF) | 977052-80-4 ; CHIRATA (SWERTIA CHIRATA BUCH.-HAM.) |
| FDA Regulation | FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION |
Physical Properties
| Food Chemicals Codex Listed | No |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | spices, other natural seasonings and flavorings |
| Recommendation for chirata usage levels up to | not for fragrance use. |
| Recommendation for chirata flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
swertia chirata buch. ham.
swertia chirata herb
PubMed:
CYP450 mediated inhibition potential of Swertia chirata: An herb from Indian traditional medicine.
PubMed:
Amarogentin regulates self renewal pathways to restrict liver carcinogenesis in experimental mouse model.
PubMed:
Antibacterial, Antifungal and antioxidant activities of some medicinal plants.
PubMed:
Expression of pro-inflammatory interleukin-8 is reduced by ayurvedic decoctions.
PubMed:
Insights from the predicted interactions of plant derived compounds to the gluco-corticoid receptor as an alternative to dexa-methasone.
PubMed:
Prevention of liver carcinogenesis by amarogentin through modulation of G1/S cell cycle check point and induction of apoptosis.
PubMed:
Insights into mechanisms underlying the gut and airways modulatory effects of Swertia chirata.
PubMed:
Highlighting the anti-carcinogenic potential of an ayurvedic medicinal plant, Swertia Chirata.
PubMed:
Report: analgesic activities of ethanol extract of leaf, stem and their different fractions of Swertia chirata.
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In vitro antimicrobial activities of different fractions of Swertia chirata ethanolic extract.
PubMed:
Protocol for in vitro regeneration and marker glycoside assessment in Swertia chirata Buch-Ham.
PubMed:
Assessment of systemic interaction between Swertia chirata extract and its Bioactive constituents in rabbits.
PubMed:
Antiviral activity of the Indian medicinal plant extract Swertia chirata against herpes simplex viruses: a study by in-vitro and molecular approach.
PubMed:
Simultaneous estimation of mangiferin and four secoiridoid glycosides in rat plasma using liquid chromatography tandem mass spectrometry and its application to pharmacokinetic study of herbal preparation.
PubMed:
Liquid chromatography/tandem mass spectrometric study and analysis of xanthone and secoiridoid glycoside composition of Swertia chirata, a potent antidiabetic.
PubMed:
Anthelmintic activity of Swertia chirata against gastrointestinal nematodes of sheep.
PubMed:
Amarogentin can reduce hyperproliferation by downregulation of Cox-II and upregulation of apoptosis in mouse skin carcinogenesis model.
PubMed:
Evaluation of the anticarcinogenic activity of Swertia chirata Buch.Ham, an Indian medicinal plant, on DMBA-induced mouse skin carcinogenesis model.
PubMed:
Phenylalanine-independent biosynthesis of 1,3,5,8-tetrahydroxyxanthone. A retrobiosynthetic NMR study with root cultures of Swertia chirata.
PubMed:
Regulation of hazardous exposure by protective exposure: modulation of phase II detoxification and lipid peroxidation by Camellia sinensis and Swertia chirata.
PubMed:
In vitro antimalarial activity of extracts of three plants used in the traditional medicine of India.
PubMed:
alpha-Glucosidase inhibitory activity of Mangifera indica bark.
PubMed:
Screening of various Swertia species extracts in primary monolayer cultures of rat hepatocytes against carbon tetrachloride- and paracetamol-induced toxicity.
PubMed:
Tyrosinase inhibitory activity of Bangladeshi indigenous medicinal plants.
PubMed:
Production of amarogentin in root cultures of Swertia chirata.
PubMed:
Review on some plants of Indian traditional medicine with antioxidant activity.
PubMed:
Superoxide-scavenging and prolyl endopeptidase inhibitory activities of Bangladeshi indigenous medicinal plants.
PubMed:
Evaluation of the in-vivo activity and toxicity of amarogentin, an antileishmanial agent, in both liposomal and niosomal forms.
PubMed:
Antihepatotoxic activity of Swertia chirata on paracetamol and galactosamine induced hepatotoxicity in rats.
PubMed:
Antihepatotoxic activity of Swertia chirata on carbon tetrachloride induced hepatotoxicity in rats.
PubMed:
Hepatoprotective effect of Swertia chirata on rat.
PubMed:
Amarogentin, a naturally occurring secoiridoid glycoside and a newly recognized inhibitor of topoisomerase I from Leishmania donovani.
PubMed:
Protective effect of Swertia chirata against indomethacin and other ulcerogenic agent-induced gastric ulcers.
PubMed:
Chemical constituents of Gentianaceae XIX: CNS-depressant effects of swertiamarin.
PubMed:
Chemical constituents of the gentianaceae V: tetraoxygenated xanthones of Swertia chirata Buch.-Ham.