bellidifolin
9H-xanthen-9-one, 1,5,8-trihydroxy-3-methoxy- (9CI)
Identification
| Name | bellidifolin |
| IUPAC | 1,5,8-trihydroxy-3-methoxyxanthen-9-one |
| CAS Number | 2798-25-6 |
| FDA UNII | Search |
| Molecular Formula | C14 H10 O6 |
| Molecular Weight | 274.22890000 |
| Nikkaji Number | J83.278B |
| Beilstein | 0288441 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 1.819 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for bellidifolin usage levels up to | not for fragrance use. |
| Recommendation for bellidifolin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
3-
methoxy-1,5,8-trihydroxyxanthen-9-one
1,5,8-
trihydroxy-3-methoxy-9H-xanthen-9-one
1,5,8-
trihydroxy-3-methoxyxanthen-9-one
9H-
xanthen-9-one, 1,5,8-trihydroxy-3-methoxy- (9CI)
PubMed:
Protective effects of bellidifolin in hypoxia-induced in pheochromocytoma cells (PC12) and underlying mechanisms.
PubMed:
Chemical constituents from Swertia mussotii Franch. (Gentianaceae).
PubMed:
[Isolation and identification of xanthones from Gentianella acuta].
PubMed:
Determination and pharmacokinetic study of four xanthones in rat plasma after oral administration of Gentianella acuta extract by UHPLC-ESI-MS/MS.
PubMed:
Two xanthones from Swertia punicea with hepatoprotective activities in vitro and in vivo.
PubMed:
Inhibition of vascular smooth muscle cell proliferation by Gentiana lutea root extracts.
PubMed:
Antimicrobial and antioxidant activities of Gentianella multicaulis collected on the Andean Slopes of San Juan Province, Argentina.
PubMed:
Activity-guided isolation of antioxidant xanthones from Swertia chirayita (Roxb.) H. Karsten (Gentianaceae).
PubMed:
Anti-diabetic effect of methylswertianin and bellidifolin from Swertia punicea Hemsl. and its potential mechanism.
PubMed:
[Determination of six active components in three species of genus Swertia by HPLC multiwavelength with detection].
PubMed:
Radioprotective effects of Gentianella austriaca fractions and polyphenolic constituents in human lymphocytes.
PubMed:
Xanthones from Gentianella amarella ssp. acuta with acetylcholinesterase and monoamine oxidase inhibitory activities.
PubMed:
[Study on chemical constituents from Swertia kauitchensis Franch].
PubMed:
Chemopreventive action of xanthone derivatives on photosensitized DNA damage.
PubMed:
Xanthones from Gentiana campestris as new acetylcholinesterase inhibitors.
PubMed:
Xanthones from Swertia punctata.
PubMed:
Bellidifolin stimulates glucose uptake in rat 1 fibroblasts and ameliorates hyperglycemia in streptozotocin (STZ)-induced diabetic rats.
PubMed:
Bellidifolin: a potent hypoglycemic agent in streptozotocin (STZ)-induced diabetic rats from Swertia japonica.
PubMed:
Mutagenicities of xanthone derivatives in Salmonella typhimurium TA100, TA98, TA97, and TA2637.