styrene oxide
benzene, (epoxyethyl)-
Identification
| Name | styrene oxide |
| CAS Number | 96-09-3 |
| EINECS | 202-476-7 |
| FDA UNII | 9QH06NGT6O |
| Molecular Formula | C8 H8 O |
| Molecular Weight | 120.15096000 |
| MDL Number | MFCD00005121 |
| Nikkaji Number | J5.159D |
| Beilstein | 0108582 |
| XlogP3 | 1.60 (est) |
Regulatory
| FDA Mainterm (IAUFC) | 96-09-3 ; STYRENE OXIDE |
Physical Properties
| Appearance | colorless to pale yellow clear liquid (est) |
| Assay | 97.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Specific Gravity | 1.05300 to 1.05600 @ 20.00 °C. |
| Pounds per Gallon - (est). | 8.772 to 8.797 |
| Refractive Index | 1.53400 to 1.53600 @ 20.00 °C. |
| Melting Point | -37.00 °C. @ 760.00 mm Hg |
| Boiling Point | 194.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 0.633000 mmHg @ 25.00 °C. (est) |
| Vapor Density | 4.14 ( Air = 1 ) |
| Flash Point | 176.00 °F. TCC ( 80.00 °C. ) |
| logP (o/w) | 1.610 |
| Soluble in | water, 3000 mg/L @ 20 °C (exp) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | oral-guinea pig LD50 2000 mg/kg |
| Dermal Toxicity | skin-rabbit LD50 890 uL/kg |
| Inhalation Toxicity | inhalation-rat LCLo 500 ppm/4H |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for styrene oxide usage levels up to | not for fragrance use. |
| Recommendation for styrene oxide flavor usage levels up to | not for flavor use. |
Potential Uses
Natural Occurrence
Synonyms
benzene, (1,2-epoxyethyl)-
benzene, (epoxyethyl)-
1,2-
epoxy-1-phenylethane
epoxyethyl benzene
1,2-
epoxyethyl benzene
epoxyethyl) benzene
epoxyethyl)benzene
epoxyethylbenzene
1,2-
epoxyethylbenzene
epoxystyrene
(±)-
epoxystyrene
oxirane, 2-phenyl-
phenethylene oxide
1-
phenyl-1,2-epoxyethane
2-
phenyl-oxirane
phenylethylene oxide
(±)-2-
phenyloxirane
1-
phenyloxirane
2-
phenyloxirane
styrene 7,8-oxide
styrene epoxide
styrene-7,8-oxide
styreneoxide
styryl oxide
PubMed:
Detection of DNA damage based on metal-mediated molecular beacon and DNA strands displacement reaction.
PubMed:
Colorimetric detection of DNA damage by using hemin-graphene nanocomposites.
PubMed:
Functional expression and magnetic nanoparticle-based Immobilization of a protein-engineered marine fish epoxide hydrolase of Mugil cephalus for enantioselective hydrolysis of racemic styrene oxide.
PubMed:
Biosynthesis of (R)-phenyl-1,2-ethanediol from racemic styrene oxide by using bacterial and marine fish epoxide hydrolases.
PubMed:
Carbon metabolism and product inhibition determine the epoxidation efficiency of solvent-tolerant Pseudomonas sp. strain VLB120DeltaC.
PubMed:
Cloning, expression and enantioselective hydrolytic catalysis of a microsomal epoxide hydrolase from a marine fish, Mugil cephalus.
PubMed:
Estimation of a possible tumorigenic risk of styrene from daily intake via food and ambient air.
PubMed:
Chronic toxicity/oncogenicity study of styrene in CD-1 mice by inhalation exposure for 104 weeks.
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Purification, molecular cloning and ethylene-inducible expression of a soluble-type epoxide hydrolase from soybean (Glycine max [L.] Merr.).
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Chronic toxicity/oncogenicity study of styrene in CD rats by inhalation exposure for 104 weeks.
PubMed:
Indigo formation by microorganisms expressing styrene monooxygenase activity.
PubMed:
Measurement of styrene oxide in polystyrenes, estimation of migration to foods, and reaction kinetics and products in food simulants.
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Possible regulatory role for nonaromatic carbon sources in styrene degradation by Pseudomonas putida CA-3.
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Effects of age and dietary restriction on liver glutathione transferase activities in Lobund-Wistar rats.
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Styrene: toxicity studies--what do they show?
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Chronic physical activity: hepatic hypertrophy and increased total biotransformation enzyme activity.
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Mechanisms of anti-carcinogenesis by indole-3-carbinol. Studies of enzyme induction, electrophile-scavenging, and inhibition of aflatoxin B1 activation.
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The study of mutagenic activity of carcinogens and other chemical agents with Salmonella typhimurium assays: testing of 126 compounds.
PubMed:
[Mutagenic activity of carcinogens and other chemical agents in Salmonella typhimurium tests].
PubMed:
Contact allergy to styrene and related chemicals.
PubMed:
Epoxide hydrolase and aryl hydrocarbon hydroxylase in human fetal tissues: activities in nuclear and microsomal fractions and in isolated hepatocytes.
PubMed:
The effect of dieldrin-contaminated feed on rat hepatic microsomal epoxide hydrase and aryl hydrocarbon hydroxylase.