octinoxate

2-propenoic acid, 3-(4-methoxyphenyl)-, 2-ethylhexyl ester

CAS: 5466-77-3 C18 H26 O3 MW: 290.40282000

Identification

Nameoctinoxate
CAS Number5466-77-3
EINECS226-775-7
FDA UNII4Y5P7MUD51
Molecular FormulaC18 H26 O3
Molecular Weight290.40282000
MDL NumberMFCD00072582
Nikkaji NumberJ210.537C
Beilstein5946632

Regulatory

Physical Properties

Appearance colorless to yellow clear liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 405.00 to 406.00 °C. @ 760.00 mm Hg (est)
Flash Point 341.00 °F. TCC ( 171.60 °C. ) (est)
logP (o/w) 5.921 (est)
Soluble in alcohol
Insoluble in water

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesuv absorbers

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic UV absorber
Recommendation for octinoxate usage levels up tonot for fragrance use.
Recommendation for octinoxate flavor usage levels up tonot for flavor use.

American International Chemical, Inc.

Consistent sources

North American supplier for globally sourced ingredients.

View All Website (800) 238-0001 info@aicma.com

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

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ECSA Chemicals

Human Chemistry

ECSA Chemicals has been active since 1913 in the trading and international commerce of raw materials. With an organisation divided into industrial segments managed by specialists, it has become one of...

View All Website +41 91 695 88 00 marketing@ecsa.ch

Jiangyin Healthway International Trade Co., Ltd

Independent Ingredients Supplier

We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.

View All Website 86-510-86023169 info@healthwaychem.com

Lluch Essence S.L.

A family company dedicated to sales and distribution

Flexibility, availability, price and quality.

View All Website 34 93 379 38 49 web@lluche.com

Moellhausen S.P.A.

THE CHEMISTRY OF EMOTIONS

Innovation and commitment in the name of excellence.

View All Website +39 039.685.6262

Penta International Corporation

Chemistry innovation

At Penta, our products and services help businesses do business better.

View All Website (973) 740-2300 lisaa@pentamfg.com

Symrise AG

Always Insiring More

Symrise aroma molecules & cosmetic ingredients for unique and innovative fragrances, flavors and cosmetics.

View All Website +49 5531 90 0 scentandcare@symrise.com

TCI AMERICA

Moving Your Chemistry Forward

We continuously strive to advance our technology.

View All Website 1-800-423-8616 Sales-US@TCIchemicals.com;

Vigon International

Passion for Simplicity

Manufacturer and supplier of high quality flavor and fragrance ingredients.

View All Website 570-476-6300 sales@vigon.com

Potential Uses

u.v. absorbers

Natural Occurrence

not found in nature

Synonyms

cinnamic acid, 4-methoxy-, 2-ethylhexyl ester escalol escalol 557 2- ethyl hexyl 4-methoxycinnamate 2- ethyl hexyl-para-methoxycinnamate 2- ethylhexyl (2E)-3-(4-methoxyphenyl)-2-propenoate 2- ethylhexyl (2E)-3-(4-methoxyphenyl)acrylate 2- ethylhexyl (2E)-3-(4-methoxyphenyl)prop-2-enoate 2- ethylhexyl (E)-3-(4-methoxyphenyl)prop-2-enoate 2- ethylhexyl 4-Methoxycinnamate 2- ethylhexyl p-methoxycinnamate 2- ethylhexyl trans-4-methoxycinnamate 2- ethylhexyl-(2E)-3-(4-methoxyphenyl)acrylat 2- ethylhexyl-4-methoxycinnamate 2- ethylhexyl-p-methoxycinnamate 2- ethylhexyl-para-methoxycinnamate eusolex 2292 4- methoxycinnamic acid 2-ethylhexyl ester 3-(4- methoxyphenyl)-2-propenoic acid 2-ethylhexyl ester 3-(4- methoxyphenyl)-2-propenoic acid, 2-ethylhexyl ester neo heliopan (Symrise) neo heliopan AV (Symrise) 2- neo heliopan AV octinoxate USP (octyl methoxycinnamate) octyl 4-methoxycinnamate octyl methoxycinnamate octyl p-Methoxycinnamate octyl para-methoxycinnamate octyl-methoxycinnamate octyl-p-methoxy cinnamate USP octyl-para-methoxycinnamate octylmethoxycinnamate OMC cinnamate parsol MCX parsol MOX 2- propenoic acid, 3- (4-methoxyphenyl)-, 2-ethylhexyl ester 2- propenoic acid, 3-(4-methoxyphenyl)-, 2-ethylhexyl ester 2- propenoic acid, 3-(4-methoxyphenyl)-, 2-ethylhexyl ester, (2E)- sunscreen AV uvinul 3088 uvinul MC 80 US Patents: 5,457,226 - Process for the manufacture of cinnamic acid derivatives PubMed: Interaction mechanisms between organic UV filters and bovine serum albumin as determined by comprehensive spectroscopy exploration and molecular docking. PubMed: Ecotoxicological evaluation of four UV filters using marine organisms from different trophic levels Isochrysis galbana, Mytilus galloprovincialis, Paracentrotus lividus, and Siriella armata. PubMed: Triplet-triplet energy transfer from a UV-A absorber butylmethoxydibenzoylmethane to UV-B absorbers. PubMed: Effects of four commonly used UV filters on the growth, cell viability and oxidative stress responses of the Tetrahymena thermophila. PubMed: Effects of in vivo exposure to UV filters (4-MBC, OMC, BP-3, 4-HB, OC, OD-PABA) on endocrine signaling genes in the insect Chironomus riparius. PubMed: Cosmetics as a potential source of environmental contamination in the UK. PubMed: Simultaneous analysis and monitoring of 16 UV filters in cosmetics by high-performance liquid chromatography. PubMed: Analysis of UV filters in tap water and other clean waters in Spain. PubMed: Evaluation of a prescription strength 4% hydroquinone/10% L-ascorbic acid treatment system for normal to oily skin. PubMed: Synthesis and evaluation of novel tetrapropoxycalix[4]arene enones and cinnamates for protection from ultraviolet radiation. PubMed: Ionic liquid-based single-drop microextraction followed by liquid chromatography-ultraviolet spectrophotometry detection to determine typical UV filters in surface water samples. PubMed: Field evaluation of three botanical repellents against Psorophora ferox, Aedes atlanticus, and Aedes mitchellae. PubMed: Chronic actinic dermatitis: clinical cases, diagnostic workup, and therapeutic management. PubMed: Polarographic determination of sunscreen agents in cosmetic products in micellar media. PubMed: Uric acid photo-oxidation assay: in vitro comparison of sunscreening agents. PubMed: Eco-friendly methodologies for the synthesis of some aromatic esters, well-known cosmetic ingredients. PubMed: UV-screening chitosan nanocontainers: increasing the photostability of encapsulated materials and controlled release. PubMed: Assessing retinol stability in a hydroquinone 4%/retinol 0.3% cream in the presence of antioxidants and sunscreen under simulated-use conditions: a pilot study. PubMed: Simultaneous electrochemical determination of three sunscreens using cetyltrimethylammonium bromide. PubMed: Transdermal penetration of UV filters. PubMed: Monitoring 2-ethylhexyl-4-methoxycinnamate photoisomerization on skin using attenuated total reflection fourier transform infrared spectroscopy. PubMed: Interactions between different solar UVB/UVA filters contained in commercial suncreams and consequent loss of UV protection. PubMed: Sun protection strength of a hydroquinone 4%/retinol 0.3% preparation containing sunscreens. PubMed: Synthesis and application of a novel sunscreen-antioxidant. PubMed: Changes in ultraviolet absorbance and hence in protective efficacy against lipid peroxidation of organic sunscreens after UVA irradiation. PubMed: Sunscreen penetration of human skin and related keratinocyte toxicity after topical application. PubMed: Unexpected photolysis of the sunscreen octinoxate in the presence of the sunscreen avobenzone. PubMed: Determination of sixteen UV filters in suncare formulations by high-performance liquid chromatography. PubMed: TiO2-promoted mineralization of organic sunscreens in water suspension and sodium dodecyl sulfate micelles. PubMed: [Determination of 4 antiseptics and 6 sunscreen agents in cosmetic products by reversed-phase high performance liquid chromatography]. PubMed: The effect of UV absorbing sunscreens on the reflectance and the consequent protection of skin. PubMed: Changes in ultraviolet absorption of sunscreens after ultraviolet irradiation. PubMed: Sunscreen allergy in Singapore. PubMed: Sunscreens offer the same UVB protection factors for inflammation and immunosuppression in the mouse. PubMed: Skin penetration and sun protection factor of ultra-violet filters from two vehicles. PubMed: Relationship between the ability of sunscreens containing 2-ethylhexyl-4'-methoxycinnamate to protect against UVR-induced inflammation, depletion of epidermal Langerhans (Ia+) cells and suppression of alloactivating capacity of murine skin in vivo.