cyclocostunolide

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(3aS-(3aalpha,5abeta,9aalpha,9bbeta))-3a,4,5,5a,6,7,9a,9b-octahydro-5a,9-dimethyl-3-methylene naphtho(1,2-b)furan-2(3H)-one

CAS: 2221-81-0 C15 H20 O2 MW: 232.32280000
All Ingredients Aromatic Ingredients CAS Numbers Found in Nature

Identification

Namecyclocostunolide
IUPAC(3aS,5aR,9aR,9bS)-5a,9-dimethyl-3-methylidene-4,5,6,7,9a,9b-hexahydro-3aH-benzo[g][1]benzofuran-2-one
CAS Number2221-81-0
FDA UNIISearch
Molecular FormulaC15 H20 O2
Molecular Weight232.32280000
Nikkaji NumberJ15.094K

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 364.00 to 365.00 °C. @ 760.00 mm Hg (est)
Flash Point 306.00 °F. TCC ( 152.30 °C. ) (est)
logP (o/w) 2.598 (est)
Soluble in water, 47.24 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for cyclocostunolide usage levels up tonot for fragrance use.
Recommendation for cyclocostunolide flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

moquinea velutina

Synonyms

(3aS,5aR,9aR,9bS)-5a,9- dimethyl-3-methylidene-4,5,6,7,9a,9b-hexahydro-3aH-benzo[g][1]benzofuran-2-one naphtho[1,2-b]furan-2(3H)-one, 3a,4,5,5a,6,7,9a,9b-octahydro-5a,9-dimethyl-3-methylene-, (3aS,5aR,9aR,9bS)- (3aS-(3aalpha,5abeta,9aalpha,9bbeta))-3a,4,5,5a,6,7,9a,9b- octahydro-5a,9-dimethyl-3-methylene naphtho(1,2-b)furan-2(3H)-one PubMed: [Chemical constituents of Dolomiaea souliei]. PubMed: [Chemical constituents from a portion of ethanolicextract of Saussurea lappa roots]. PubMed: Antitrypanosomal sesquiterpene lactones from Saussurea costus. PubMed: A new sesquiterpene and other constituents from Saussurea lappa root. PubMed: A new sesquiterpene lactone from the roots of Saussurea lappa: structure-anticancer activity study. PubMed: PTP1B inhibitors from Saussrurea lappa. PubMed: Volatile components of selected species of the liverwort genera Frullania and Schusterella (Frullaniaceae) from New Zealand, Australia and South America: a chemosystematic approach. PubMed: Occupational erythema-multiforme-like dermatitis from sensitization to costus resinoid, followed by flare-up and systemic contact dermatitis from beta-cyclocostunolide in a chemistry student. PubMed: Chemical constituents of two Chinese Magnoliaceae plants, Tsoongiodendron odorum and Manglietiastrum sinicum, and their inhibition of platelet aggregation. PubMed: Chemoprophylactic agents in schistosomiasis: eremanthine, costunolide, -cyclocostunolide and bisabolol.