neohesperidin dihydrochalcone
neohesperidin DC
Identification
| Name | neohesperidin dihydrochalcone |
| IUPAC | 1-[4-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-2,6-dihydroxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)propan-1-one |
| CAS Number | 20702-77-6 |
| EINECS | 243-978-6 |
| FDA UNII | 3X476D83QV |
| Molecular Formula | C28 H36 O15 |
| Molecular Weight | 612.58292000 |
| MDL Number | MFCD00017711 |
| Nikkaji Number | J2.757J |
Regulatory
| FDA/DG SANTE Petitions, Reviews, Notices | GRN 902 |
| DG SANTE Food Flavourings | 16.061 neohesperidin dihydrochalcone |
| DG SANTE Food Additives | neohesperidin dihydrochalcone |
| FEMA Number | 3811 |
| FDA | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF) | 20702-77-6 ; NEOHESPERIDIN DIHYDROCHALCONE |
Physical Properties
| Appearance | white to pale yellow powder (est) |
| Assay | 96.00 to 100.00 sum of isomers |
| Food Chemicals Codex Listed | No |
| Melting Point | 156.00 to 158.00 °C. @ 760.00 mm Hg |
| Boiling Point | 927.13 °C. @ 760.00 mm Hg (est) |
| Flash Point | > 200.00 °F. TCC ( > 93.33 °C. ) |
| logP (o/w) | 0.205 (est) |
| Soluble in | water, 342.1 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | ['cosmetic data2', 'cosmetic data'] |
| Cosmetic Uses | flavoring agents |
Organoleptic Properties
| Odor Strength | none |
| Odor Description |
at 100.00 %. No apparent odor
|
| Odor sample from | CA Aromatics Company Inc. |
| Taste Description | at 10.00 ppm. |
Safety Information
| Preferred SDS | View |
| European information | Most important hazard(s): |
| Oral/Parenteral Toxicity | oral-rat LD50 [sex: M,F] > 5000 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic and flavor agents |
| Recommendation for neohesperidin dihydrochalcone usage levels up to | not for fragrance use. |
| Maximised Survey-derived Daily Intakes (MSDI-EU) | 12.00 (μg/capita/day) |
| Modified Theoretical Added Maximum Daily Intake (mTAMDI) | 1400 (μg/person/day) |
| Threshold of Concern | 90 (μg/person/day) |
| Structure Class | III |
| baked goods | 5.00000 |
| beverages(nonalcoholic) | 5.00000 |
| beverages(alcoholic) | 5.00000 |
| breakfast cereal | 8.00000 |
| cheese | 3.00000 |
| chewing gum | 200.00000 |
| condiments / relishes | 2.00000 |
| confectionery froastings | 3.00000 |
| egg products | 2.00000 |
| fats / oils | 4.00000 |
| fish products | 2.00000 |
| frozen dairy | 2.00000 |
| fruit ices | 2.00000 |
| gelatins / puddings | 3.00000 |
| granulated sugar | - |
| gravies | 3.00000 |
| hard candy | 5.00000 |
| imitation dairy | 3.00000 |
| instant coffee / tea | 3.00000 |
| jams / jellies | 2.00000 |
| meat products | 2.00000 |
| milk products | 3.00000 |
| nut products | 3.00000 |
| other grains | 3.00000 |
| poultry | 2.00000 |
| processed fruits | 2.00000 |
| processed vegetables | 2.00000 |
| reconstituted vegetables | 2.00000 |
| seasonings / flavors | 3.00000 |
| snack foods | 3.00000 |
| soft candy | 4.00000 |
| soups | 5.00000 |
| sugar substitutes | - |
| sweet sauces | 2.00000 |
| Dairy products, excluding products of category 02.0 (01.0) | 2.00000 |
| Fats and oils, and fat emulsions (type water-in-oil) (02.0) | 4.00000 |
| Edible ices, including sherbet and sorbet (03.0) | 1.00000 |
| Processed fruit (04.1) | 2.00000 |
| Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2) | - |
| Confectionery (05.0) | 2.00000 |
| Chewing gum (05.3) | - |
| Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0) | 3.00000 |
| Bakery wares (07.0) | 4.00000 |
| Meat and meat products, including poultry and game (08.0) | 2.00000 |
| Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0) | 2.00000 |
| Eggs and egg products (10.0) | 2.00000 |
| Sweeteners, including honey (11.0) | - |
| Salts, spices, soups, sauces, salads, protein products, etc. (12.0) | 2.00000 |
| Foodstuffs intended for particular nutritional uses (13.0) | - |
| Non-alcoholic ("soft") beverages, excl. dairy products (14.1) | 2.00000 |
| Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2) | 2.00000 |
| Ready-to-eat savouries (15.0) | 2.00000 |
| Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0) | - |
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