osajin
4H,8H-benzo(1,2-b:3,4-b')dipyran-4-one, 5-hydroxy-3-(p-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-butenyl)-
Identification
| Name | osajin |
| IUPAC | 5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methylbut-2-enyl)pyrano[2,3-h]chromen-4-one |
| CAS Number | 482-53-1 |
| FDA UNII | 83R5N9X74B |
| Molecular Formula | C25 H24 O5 |
| Molecular Weight | 404.46228000 |
| MDL Number | MFCD00076045 |
| Nikkaji Number | J13.174A |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 0.005882 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antioxidants |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | antioxidants |
| Recommendation for osajin usage levels up to | not for fragrance use. |
| Recommendation for osajin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
4H,8H-
benzo(1,2-b:3,4-b')dipyran-4-one, 5-hydroxy-3-(p-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-butenyl)-
4H,8H-
benzo[1,2-b:3,4-b']dipyran-4-one, 5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-buten-1-yl)-
5-
hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-buten-1-yl)-4H,8H-pyrano[2,3-f]chromen-4-one
5-
hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methylbut-2-enyl)pyrano[2,3-H]chromen-4-one
PubMed:
Potential of Horse Apple Isoflavones in Targeting Inflammation and Tau Protein Fibrillization.
PubMed:
Semi-synthetic derivatives of natural isoflavones from Maclura pomifera as a novel class of PDE-5A inhibitors.
PubMed:
Effect of osajin and pomiferin on antidiabetic effects from normal and streptozotocin-induced diabetic rats.
PubMed:
In vitro and ex vivo examination of topical Pomiferin treatments.
PubMed:
Prenylated and geranylated flavonoids increase production of reactive oxygen species in mouse macrophages but inhibit the inflammatory response.
PubMed:
HPLC determination of isoflavone levels in osage orange from the Midwest and southern United States.
PubMed:
Antiproliferative activity of pomiferin in normal (MCF-10A) and transformed (MCF-7) breast epithelial cells.
PubMed:
Activation of multiple apoptotic pathways in human nasopharyngeal carcinoma cells by the prenylated isoflavone, osajin.
PubMed:
Vapor-phase toxicity of Derris scandens Benth.-derived constituents against four stored-product pests.
PubMed:
Examining the genomic influence of skin antioxidants in vitro.
PubMed:
[Flavonoids from roots of Flemingia philippinensis].
PubMed:
Cholinesterase inhibitory effects of the extracts and compounds of Maclura pomifera (Rafin.) Schneider.
PubMed:
Electrochemical and spectrometric study of antioxidant activity of pomiferin, isopomiferin, osajin and catalposide.
PubMed:
[Testing of antidiabetic and antioxidative effect of the flavonoid osajin in an experiment].
PubMed:
Pomiferin, histone deacetylase inhibitor isolated from the fruits of Maclura pomifera.
PubMed:
Effects of prenylated isoflavones osajin and pomiferin in premedication on heart ischemia-reperfusion.
PubMed:
[Protective effects of the flavonoids osajin and pomiferin on heart ischemia-reperfusion].
PubMed:
Interactions of genistein and related isoflavones with lipid micelles.
PubMed:
Protective effects of osajin in ischemia-reperfusion of laboratory rat kidney.
PubMed:
Neuroprotective flavonoids from Flemingia macrophylla.
PubMed:
Antioxidative and EROD activities of osajin and pomiferin.
PubMed:
Antioxidant isoflavones in Osage orange, Maclura pomifera (Raf.) Schneid.
PubMed:
Isolation of 19alpha-H-lupeol from Maclura pomifera.
PubMed:
Inhibition of valyl angiotensinamide II by osajin.
PubMed:
Osage orange pigments; complete structures of osajin and pomiferin.