paeonia lactiflora root
root of the peony, paeonia lactiflora, ranunculaceae
Identification
| Name | paeonia lactiflora root |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic ingredient for skin conditioning |
| Recommendation for paeonia lactiflora root usage levels up to | not for fragrance use. |
| Recommendation for paeonia lactiflora root flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
chinese
peony root
garden
peony root
root of the peony, paeonia lactiflora, ranunculaceae
PubMed:
[Analysis of Monosaccharide Compositions in Paeoniae Radix Alba Polysaccharide].
PubMed:
Hematopoietic Effects of Paeoniflorin and Albiflorin on Radiotherapy-Induced Myelosuppression Mice.
PubMed:
[Comparative study of biological characters and paeoniflorin content of wild and asexual cultivated Paeonia lactiflora growing at Duolun county, Inner Mongolia].
PubMed:
Paeoniflorin prevents hypoxia-induced epithelial-mesenchymal transition in human breast cancer cells.
PubMed:
Metabolomics Coupled with Multivariate Data and Pathway Analysis on Potential Biomarkers in Cholestasis and Intervention Effect of Paeonia lactiflora Pall.
PubMed:
Chemical constituents with anti-allergic activity from the root of Edulis Superba, a horticultural cultivar of Paeonia lactiflora.
PubMed:
The skin depigmenting potential of Paeonia lactiflora root extract and Paeoniflorin: in vitro evaluation using reconstructed pigmented human epidermis.
PubMed:
Nondestructive estimation of growth year in ginseng cultivars using the means of mathematical modeling on the basis of allometry.
PubMed:
Monoterpene derivatives with anti-allergic activity from red peony root, the root of Paeonia lactiflora.
PubMed:
Not only serotonergic system, but also dopaminergic system involved in albiflorin against chronic unpredictable mild stress-induced depression-like behavior in rats.
PubMed:
Protective Effects of Total Glucosides of Paeony on N-nitrosodiethylamine-induced Hepatocellular Carcinoma in Rats via Down-regulation of Regulatory B Cells.
PubMed:
Paeoniflorin attenuates Aβ1-42-induced inflammation and chemotaxis of microglia in vitro and inhibits NF-κB- and VEGF/Flt-1 signaling pathways.
PubMed:
Antiviral activity and possible mechanism of action of constituents identified in Paeonia lactiflora root toward human rhinoviruses.
PubMed:
Lignans from the root of Paeonia lactiflora and their anti-β-amyloid aggregation activities.
PubMed:
Paeoniflorin inhibits skin lesions in imiquimod-induced psoriasis-like mice by downregulating inflammation.
PubMed:
Whole transverse section and specific-tissue analysis of secondary metabolites in seven different grades of root of Paeonia lactiflora using laser microdissection and liquid chromatography-quadrupole/time of flight-mass spectrometry.
PubMed:
Differences in the chemical profiles and biological activities of Paeonia lactiflora and Paeonia obovata.
PubMed:
Genetic and chemical characterization of white and red peony root derived from Paeonia lactiflora.
PubMed:
Pharmacokinetic comparisons by UPLC-MS/MS of isomer paeoniflorin and albiflorin after oral administration decoctions of single-herb Radix Paeoniae Alba and Zengmian Yiliu prescription to rats.
PubMed:
Paeoniflorin protects cells from GalN/TNF-α-induced apoptosis via ER stress and mitochondria-dependent pathways in human L02 hepatocytes.
PubMed:
Characterization of the anti-influenza activity of the Chinese herbal plant Paeonia lactiflora.
PubMed:
Counteractive effect of Paeonia lactiflora root constituent mudanpioside E against suppressive effect of Shoseiryuto-extract on passive cutaneous anaphylaxis reaction in mice.
PubMed:
[Varieties, functions and clinical applications of Chishao and Baishao: a literature review].
PubMed:
Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway.
PubMed:
Functional diversity of genes for the biosynthesis of paeoniflorin and its derivatives in Paeonia.
PubMed:
Establishment of a methodology for identifying Paeoniae Radix based on metallomic analysis.
PubMed:
Pharmacokinetic comparisons of two different combinations of Shaoyao-Gancao Decoction in rats: competing mechanisms between paeoniflorin and glycyrrhetinic acid.
PubMed:
Paeoniflorin suppresses vascular damage and the expression of E-selectin and ICAM-1 in a mouse model of cutaneous Arthus reaction.
PubMed:
Paeonol attenuates inflammation-mediated neurotoxicity and microglial activation.
PubMed:
Neuroprotective effects of paeoniflorin, but not the isomer albiflorin, are associated with the suppression of intracellular calcium and calcium/calmodulin protein kinase II in PC12 cells.
PubMed:
Inhibitory effects of Korean indigenous plants on tyrosinase and melanogenesis.
PubMed:
Paeoniflorin, a monoterpene glycoside, attenuates lipopolysaccharide-induced neuronal injury and brain microglial inflammatory response.
PubMed:
Application of quantitative 1H-NMR method to determination of paeoniflorin in Paeoniae radix.
PubMed:
Growth-inhibiting, bactericidal, and urease inhibitory effects of Paeonia lactiflora root constituents and related compounds on antibiotic-susceptible and -resistant strains of Helicobacter pylori.
PubMed:
Growth-inhibiting effects of Paeonia lactiflora root steam distillate constituents and structurally related compounds on human intestinal bacteria.
PubMed:
Mechanisms involved in the therapeutic effects of Paeonia lactiflora Pallas in rheumatoid arthritis.
PubMed:
Identification of ages and determination of paeoniflorin in roots of Paeonia lactiflora Pall. From four producing areas based on growth rings.
PubMed:
Paeoniae radix reduces PDGF-stimulated hepatic stellate cell migration.
PubMed:
BAFF/BAFF-R involved in antibodies production of rats with collagen-induced arthritis via PI3K-Akt-mTOR signaling and the regulation of paeoniflorin.
PubMed:
Protective effects of paeoniflorin against cobalt chloride-induced apoptosis of endothelial cells via HIF-1α pathway.
PubMed:
Anti-depressant-like effect of peony: a mini-review.
PubMed:
Paeoniflorin inhibits function of synoviocytes pretreated by rIL-1α and regulates EP4 receptor expression.
PubMed:
Influence of Paeonia lactiflora roots extract on cAMP-phosphodiesterase activity and related anti-inflammatory action.
PubMed:
Protective effects of peoniflorin against hydrogen peroxide-induced oxidative stress in human umbilical vein endothelial cells.
PubMed:
Pharmacological evaluation of insulin mimetic novel suppressors of PEPCK gene transcription from Paeoniae Rubra Radix.
PubMed:
Anti-inflammatory and immunomodulatory effects of paeonia lactiflora pall., a traditional chinese herbal medicine.
PubMed:
Identification of novel pregnane X receptor activators from traditional Chinese medicines.
PubMed:
[RP-HPLC determination of main chemical components in different parts and different harvest periods of Paeonia lactiflora].
PubMed:
Peoniflorin suppresses tumor necrosis factor-α induced chemokine production in human dermal microvascular endothelial cells by blocking nuclear factor-κB and ERK pathway.
PubMed:
Platelet anti-aggregatory and blood anti-coagulant effects of compounds isolated from Paeonia lactiflora and Paeonia suffruticosa.
PubMed:
The effects of paeoniflorin on LPS-induced liver inflammatory reactions.
PubMed:
Long-term treatment with peony glycosides reverses chronic unpredictable mild stress-induced depressive-like behavior via increasing expression of neurotrophins in rat brain.
PubMed:
Pharmacokinetic comparisons of typical constituents in white peony root and sulfur fumigated white peony root after oral administration to mice.
PubMed:
Effects of total glucosides of paeony on oxidative stress in the kidney from diabetic rats.
PubMed:
Analgesic effect of paeoniflorin in rats with neonatal maternal separation-induced visceral hyperalgesia is mediated through adenosine A(1) receptor by inhibiting the extracellular signal-regulated protein kinase (ERK) pathway.
PubMed:
[Effects of Mn, Fe, Zn and Cu on growth and paeoniflorin content of Paeonia lactiflora].
PubMed:
Peony glycosides produce antidepressant-like action in mice exposed to chronic unpredictable mild stress: effects on hypothalamic-pituitary-adrenal function and brain-derived neurotrophic factor.
PubMed:
Effect of total glucosides of paeony on the expression of nephrin in the kidneys from diabetic rats.
PubMed:
Effects of peony glycosides on mice exposed to chronic unpredictable stress: further evidence for antidepressant-like activity.
PubMed:
[Analysis of Paeonia lactiflora by X-ray diffraction Fourier pattern method].
PubMed:
Renoprotective effect of total glucosides of paeony (TGP) and its mechanism in experimental diabetes.
PubMed:
Paeonol attenuates neurotoxicity and ameliorates cognitive impairment induced by d-galactose in ICR mice.
PubMed:
[Study on balanced application of NPK fertilizer on growth of Paeonia lactiflora with orthogonal design].
PubMed:
Antidepressant-like effect of peony glycosides in mice.
PubMed:
[Dynamic change of paeoniflorin content in root of Paeonia lactiflora growing at Duolun County, Inner Mongolia].
PubMed:
Species differentiation and quality assessment of Radix Paeoniae Rubra (Chi-shao) by means of high-performance liquid chromatographic fingerprint.
PubMed:
[The development and evolution of differentiation between Radix Paeoniae Rubra and Radix Paeoniae Alba].
PubMed:
Antiallergic effect of the root of Paeonia lactiflora and its constituents paeoniflorin and paeonol.
PubMed:
The analgesic effect of paeoniflorin on neonatal maternal separation-induced visceral hyperalgesia in rats.
PubMed:
Antinociceptive effects of systemic paeoniflorin on bee venom-induced various 'phenotypes' of nociception and hypersensitivity.
PubMed:
[Quantititive study for chromatographic fingerprints of processed products of Paeonia lactiflora].
PubMed:
Paeoniflorin induced immune tolerance of mesenteric lymph node lymphocytes via enhancing beta 2-adrenergic receptor desensitization in rats with adjuvant arthritis.
PubMed:
In vitro antiviral activity of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose against hepatitis B virus.
PubMed:
A new phenolic glycoside from Paeonia lactiflora.
PubMed:
Protective effect of paeoniflorin on immunological liver injury induced by bacillus Calmette-Guerin plus lipopolysaccharide: modulation of tumour necrosis factor-alpha and interleukin-6 MRNA.
PubMed:
[Study on the original plants and macroscopic characters of Radix Paeoniae].
PubMed:
Paeonol reduced cerebral infarction involving the superoxide anion and microglia activation in ischemia-reperfusion injured rats.
PubMed:
Pharmacokinetic interaction of paeoniflorin and sinomenine: pharmacokinetic parameters and tissue distribution characteristics in rats and protein binding ability in vitro.
PubMed:
Inhibitory action of L-type Ca2+ current by paeoniflorin, a major constituent of peony root, in NG108-15 neuronal cells.
PubMed:
The effects of sinomenine on intestinal absorption of paeoniflorin by the everted rat gut sac model.
PubMed:
Antioxidative constituents from Paeonia lactiflora.
PubMed:
Influence of co-administrated sinomenine on pharmacokinetic fate of paeoniflorin in unrestrained conscious rats.
PubMed:
[Rapid identification of Cortex moutan radicis and similar aromatic Chinese herbs by headspace gas chromatography].
PubMed:
Effects of Paeonia lactiflora root extracts on the secretions of monocyte chemotactic protein-1 and -3 in human nasal fibroblasts.
PubMed:
A deglucosylated metabolite of paeoniflorin of the root of Paeonia lactiflora and its pharmacokinetics in rats.
PubMed:
Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity by 1,2,3,4,6-penta-O-galloyl-beta-D-glucose in murine macrophage cells.
PubMed:
[A study on genetic variation between wild and cultivated populations of Paeonia lactiflora Pall].
PubMed:
Paeoniae Radix, a Chinese herbal extract, inhibit hepatoma cells growth by inducing apoptosis in a p53 independent pathway.
PubMed:
The inhibition of phenylhydroquinone-induced oxidative DNA cleavage by constituents of Moutan Cortex and Paeoniae Radix.
PubMed:
Paeoniflorin reverses guanethidine-induced hypotension via activation of central adenosine A1 receptors in Wistar rats.
PubMed:
Antihyperglycemic effects of paeoniflorin and 8-debenzoylpaeoniflorin, glucosides from the root of Paeonia lactiflora.
PubMed:
An acidic polysaccharide with immunological activities from the root of Paeonia lactiflora.
PubMed:
Characterization of a neutral and an acidic polysaccharide having immunological activities from the root of Paeonia lactiflora.
PubMed:
Pharmacotherapeutic effects of kuei-chih-fu-ling-wan (keishi-bukuryo-gan) on human uterine myomas.
PubMed:
[Protective mechanism of Salvia miltiorrhiza and Paeonia lactiflora for experimental liver damage].
PubMed:
[A preliminary study on the pharmacology of the compound prescription huangqin tang and its component drugs].
PubMed:
Effects of a Chinese herbal medicine, keishi-bukuryo-gan, on the gonadal system of rats.
PubMed:
Effects of certain herbal medicines on the biotransformation of arachidonic acid: a new pharmacological testing method using serum.
PubMed:
[STUDIES ON THE CHEMICAL CONSTITUENTS OF THE CHINESE MEDICAL DRUG, ROOT OF PAEONIA LACTIFLORA PALL].