gambir
uncaria gambir roxb.
Identification
| Name | gambir |
| CAS Number | 8001-48-7 |
| FDA UNII | 3NJQ5D8S6N |
| Molecular Formula | unspecified |
Regulatory
| FDA Mainterm (SATF) | 8001-48-7 ; GAMBIR (UNCARIA GAMBIR ROXB.) |
| FDA Regulation | FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION |
Physical Properties
| Food Chemicals Codex Listed | No |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | flavor and texture modifiers |
| Recommendation for gambir usage levels up to | not for fragrance use. |
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Potential Uses
Natural Occurrence
Synonyms
catechu
gambir catechu
pale catechu
uncaria gambir roxb.
PubMed:
Gambir, "Gambir Sarawak" and toad venom.
PubMed:
A novel α-glucosidase inhibitory constituent from Uncaria gambir.
PubMed:
Cytotoxic data of 14-deoxy-11, 12-didehydroandrographolide (14-DDA), double transfection and DDIT3 silencing data in T-47D breast carcinoma cells.
PubMed:
14-Deoxy-11,12-didehydroandrographolide induces DDIT3-dependent endoplasmic reticulum stress-mediated autophagy in T-47D breast carcinoma cells.
PubMed:
Development of resazurin-based assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei rhodesiense strain STIB 900 for the identification of potential anti-trypanosomal agents.
PubMed:
Molecular modelling, synthesis and biological evaluation of peptide inhibitors as anti-angiogenic agent targeting neuropilin-1 for anticancer application.
PubMed:
H274Y's Effect on Oseltamivir Resistance: What Happens Before the Drug Enters the Binding Site.
PubMed:
Potent PPARγ Ligands from Swietenia macrophylla Are Capable of Stimulating Glucose Uptake in Muscle Cells.
PubMed:
A simple and simultaneous identification method for aloe, catechu and gambir by high performance liquid chromatography.
PubMed:
Targeting Heat Shock Proteins 60 and 70 of Toxoplasma gondii as a Potential Drug Target: In Silico Approach.
PubMed:
Analgesic and anti-Inflammatory effect of UP3005, a botanical composition Containing two standardized extracts of Uncaria gambir and Morus alba.
PubMed:
Binding specificity of polypeptide substrates in NS2B/NS3pro serine protease of dengue virus type 2: A molecular dynamics Study.
PubMed:
UP3005, a Botanical Composition Containing Two Standardized Extracts of Uncaria gambir and Morus alba, Improves Pain Sensitivity and Cartilage Degradations in Monosodium Iodoacetate-Induced Rat OA Disease Model.
PubMed:
Potential inhibitors for isocitrate lyase of Mycobacterium tuberculosis and non-M. tuberculosis: a summary.
PubMed:
A virtual screening approach for identifying plants with anti H5N1 neuraminidase activity.
PubMed:
The capacity for long-chain polyunsaturated fatty acid synthesis in a carnivorous vertebrate: Functional characterisation and nutritional regulation of a Fads2 fatty acyl desaturase with Î4 activity and an Elovl5 elongase in striped snakehead (Channa striata).
PubMed:
Cytochrome P450 induction properties of food and herbal-derived compounds using a novel multiplex RT-qPCR in vitro assay, a drug-food interaction prediction tool.
PubMed:
In Silico Investigation of a HIV-1 Vpr Inhibitor Binding Site: Potential for Virtual Screening and anti-HIV Drug Design.
PubMed:
The mTOR signalling pathway in cancer and the potential mTOR inhibitory activities of natural phytochemicals.
PubMed:
Synthesis of novel derivatives of 4-methylbenzimidazole and evaluation of their biological activities.
PubMed:
9-Benzyl-6-benzyl-sulfanyl-9H-purin-2-amine.
PubMed:
Diagnosis of periprosthetic joint infection.
PubMed:
Diagnosis of periprosthetic joint infection.
PubMed:
Antioxidant and cytoprotective activities of Piper betle, Areca catechu, Uncaria gambir and betel quid with and without calcium hydroxide.
PubMed:
The effect of mitragynine on cAMP formation and mRNA expression of mu-opioid receptors mediated by chronic morphine treatment in SK-N-SH neuroblastoma cell.
PubMed:
Cardioankle vascular index evaluations revealed that cotreatment of ARB Antihypertension medication with traditional Chinese medicine improved arterial functionality.
PubMed:
Cytotoxic and Apoptotic Effects of Ethyl Acetate Extract of Elephantopus mollis Kunth. in Human Liver Carcinoma HepG2 Cells Through Caspase-3 Activation.
PubMed:
Mitragynine attenuates withdrawal syndrome in morphine-withdrawn zebrafish.
PubMed:
Identification of genes involved in the regulation of 14-deoxy-11,12-didehydroandrographolide-induced toxicity in T-47D mammary cells.
PubMed:
Genetic variation of glucose transporter-1 (GLUT1) and albuminuria in 10,278 European Americans and African Americans: a case-control study in the Atherosclerosis Risk in Communities (ARIC) study.
PubMed:
Antinociceptive and antiinflammatory activities of the aqueous extract of Trigonopleura malayana resin in experimental animal models.
PubMed:
[The history of tooth dyeing].
PubMed:
[Evaluation of gambir quality based on quantitative analysis of polyphenolic constituents].
PubMed:
Revised structures of gambiriins A1, A2, B1, and B2, chalcane-flavan dimers from gambir (Uncaria gambir extract).
PubMed:
Antimicrobial susceptibility of community-acquired uropathogens in general practice.
PubMed:
[The health benefits of gambir].
PubMed:
[Traditional nostrum].
PubMed:
[A gambir recipe brought by Ganjin, a Chinese buddhist dignitary].
PubMed:
[China-home of the tea drinking custom].
PubMed:
[The roots of Cha and Gambir].
PubMed:
[Pharmacological action of Gambir.].
PubMed:
[Recognize uncalia ganbir].
PubMed:
Effective medicinal plants against enterohaemorrhagic Escherichia coli O157:H7.
PubMed:
Effects of herbal drugs prescribed in wood creosote pills on the dissolution profile of guaiacol.
PubMed:
[Gambir revisted].
PubMed:
Direct scavenging of nitric oxide by traditional crude drugs.
PubMed:
Lupus miliaris disseminatus faciei.
PubMed:
Widespread tannin intake via stimulants and masticatories, especially guarana, kola nut, betel vine, and accessories.
PubMed:
Liposarcoma of the cheek.
PubMed:
The effects of betel-nut chewing on the buccal mucosa of 296 Indians and Malays in West Malaysia. A clinical study.
PubMed:
Gambirdine and isogambirdine, the alkaloids from Uncaria gambir (Hunt) Roxb.
PubMed:
Studies on flavonoid metabolism. Biosynthesis of (+)-[14C]catechin by the plant Uncaria gambir Roxb.