beta-thujaplicin

2,4,6- cycloheptatrien-1-one, 2-hydroxy-4-(1-methylethyl)- 2,4,6- cycloheptatrien-1-one, 2-hydroxy-4-isopropyl- 2,4,6- cycloheptatrien-1-one, 2-hydroxy-6-(1-methylethyl)- hinokitiol hinokitiol crystals hinokitiol crystals (takasago) hinokitol 2- hydroxy-4-(1-methyl ethyl)-2,4,6-cycloheptatrien-1-one 2- hydroxy-4-(1-methylethyl)-2,4,6-cycloheptatrien-1-one 2- hydroxy-4-(methylethyl)cyclohepta-2,4,6-trien-1-one 2- hydroxy-4-isopropyl-2,4, 6-cycloheptatrien-1-one 2- hydroxy-4-isopropyl-2,4,6-cyclohepta-2,4,6-trien-1-one 2- hydroxy-4-isopropyl-2,4,6-cycloheptatrien-1-one 2- hydroxy-4-isopropyl-cyclohepta-2,4,6-trienone 2- hydroxy-4-isopropylcyclohepta-2,4,6-trien-1-one 2- hydroxy-4-isopropylcyclohepta-2,4,6-trienone 2- hydroxy-6-(propan-2-yl)cyclohepta-2,4,6-trien-1-one 2- hydroxy-6-isopropyl-2,4,6-cycloheptatrien-1-one 2- hydroxy-6-propan-2-ylcyclohepta-2,4,6-trien-1-one beta-iso propyl tropolon 4-iso propyl tropolone iso propyl tropolone 4-iso propyltropolone beta- thujaplicin beta- thujaplicine tropolone, 4-isopropyl- PubMed: Toxicity of hiba oil constituents and spray formulations to American house dust mites and copra mites. PubMed: A novel synthetic pathway for tropolone ring formation via the olefin monoterpene intermediate terpinolene in cultured Cupressus lusitanica cells. PubMed: Hinokitiol inhibits cell growth through induction of S-phase arrest and apoptosis in human colon cancer cells and suppresses tumor growth in a mouse xenograft experiment. PubMed: Hinokitiol, a natural tropolone derivative, offers neuroprotection from thromboembolic stroke in vivo. PubMed: Determination of hinokitiol in skin lotion by high-performance liquid chromatography-ultraviolet detection after precolumn derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole. PubMed: Effect of mouth cleaning with hinokitiol-containing gel on oral malodor: a randomized, open-label pilot study. PubMed: Tetsuo Nozoe's "Autograph Books by Chemists 1953-1994": an essay. PubMed: Hinokitiol inhibits platelet activation ex vivo and thrombus formation in vivo. PubMed: In vitro antimicrobial and anticancer potential of hinokitiol against oral pathogens and oral cancer cell lines. PubMed: Stress-related activities induced by predator odor may become indistinguishable by hinokitiol odor. PubMed: In vitro and in vivo anti-plasmodial activity of essential oils, including hinokitiol. PubMed: The furan route to tropolones: probing the antiproliferative effects of β-thujaplicin analogs. PubMed: In vitro and in vivo therapeutics of β-thujaplicin on LPS-induced inflammation in macrophages and septic shock in mice. PubMed: Preventive effects of β-thujaplicin against UVB-induced MMP-1 and MMP-3 mRNA expressions in skin fibroblasts. PubMed: Effects of a combination of hinokitiol (β-thujaplicin) and an organic acid mixture on ruminal fermentation in heifers fed a high-grain diet. PubMed: In vitro Na+/K+-ATPase inhibitory activity and antimicrobial activity of sesquiterpenes isolated from Thujopsis dolabrata. PubMed: A 13-week subchronic toxicity study of hinokitiol administered in the diet to F344 rats. PubMed: Zinc-dependent effects of small molecules on the insulin-sensitive transcription factor FOXO1a and gluconeogenic genes. PubMed: Structural insights into the hot spot amino acid residues of mushroom tyrosinase for the bindings of thujaplicins. PubMed: Inhibitory effects of hinokitiol on tyrosinase activity and melanin biosynthesis and its antimicrobial activities. PubMed: Hinokitiol activates the hypoxia-inducible factor (HIF) pathway through inhibition of HIF hydroxylases. PubMed: Time-kill assay results for a linalool-hinokitiol-based eyelid cleanser for lid hygiene. PubMed: In vitro skin permeation of hinokitiol loaded in vesicles composed of behenyltrimethylammonium chloride and stearic acid. PubMed: Synthesis of tropolone derivatives and evaluation of their in vitro neuroprotective activity. PubMed: High-performance liquid chromatography with dual-wavelength ultraviolet detection for measurement of hinokitiol in personal care products. PubMed: p27-Associated G1 arrest induced by hinokitiol in human malignant melanoma cells is mediated via down-regulation of pRb, Skp2 ubiquitin ligase, and impairment of Cdk2 function. PubMed: Effects of leaching on fungal growth and decay of western redcedar. PubMed: Volatile and non-volatile monoterpenes produced by elicitor-stimulated Cupressus lusitanica cultured cells. PubMed: Antiviral activity of the zinc ionophores pyrithione and hinokitiol against picornavirus infections. PubMed: High production of beta-thujaplicin glycosides by immobilized plant cells of Nicotiana tabacum. PubMed: Hinokitiol, a natural tropolone derivative, inhibits TNF-alpha production in LPS-activated macrophages via suppression of NF-kappaB. PubMed: In vivo hair growth promotion effects of cosmetic preparations containing hinokitiol-loaded poly(epsilon-caprolacton) nanocapsules. PubMed: Antifungal mechanism of hinokitiol against Candida albicans. PubMed: In vitro permeation study of hinokitiol: effects of vehicles and enhancers. PubMed: Antifungal properties of ethanolic extract and its active compounds from Calocedrus macrolepis var. formosana (Florin) heartwood. PubMed: The mechanism of the bactericidal activity of hinokitiol. PubMed: Growth inhibitory effect of shelf life extending agents on Bacillus subtilis IAM 1026. PubMed: Reactive oxygen species, nitric oxide, and their interactions play different roles in Cupressus lusitanica cell death and phytoalexin biosynthesis. PubMed: Analysis of western redcedar (Thuja plicata Donn) heartwood components by HPLC as a possible screening tool for trees with enhanced natural durability. PubMed: Lack of hinokitiol (beta-thujaplicin) carcinogenicity in F344/DuCrj rats. PubMed: Hinokitiol, a metal chelator derived from natural plants, suppresses cell growth and disrupts androgen receptor signaling in prostate carcinoma cell lines. PubMed: The excellence of Aomori Hiba (Hinokiasunaro) in its use as building materials of Buddhist temples and Shinto shrines. PubMed: Differential regulation of melanosomal proteins after hinokitiol treatment. PubMed: Therapeutic effects of beta-thujaplicin eardrops on canine Malassezia-related otitis externa. PubMed: Mosquito larvicidal activity of active constituent derived from Chamaecyparis obtusa leaves against 3 mosquito species. PubMed: Effects of beta-thujaplicin on anti-Malassezia pachydermatis remedy for canine otitis externa. PubMed: Human metallothionein gene expression is upregulated by beta-thujaplicin: possible involvement of protein kinase C and reactive oxygen species. PubMed: Prooxidant action of hinokitiol: hinokitiol-iron dependent generation of reactive oxygen species. PubMed: Inhibitory effects of 4-n-butylresorcinol on tyrosinase activity and melanin synthesis. PubMed: Signal transduction and metabolic flux of beta-thujaplicin and monoterpene biosynthesis in elicited Cupressus lusitanica cell cultures. PubMed: In vitro inhibitory effects of hinokitiol on proliferation of Chlamydia trachomatis. PubMed: Oxidative stress in plant cell culture: a role in production of beta-thujaplicin by Cupresssus lusitanica suspension culture. PubMed: Fungal diversity from western redcedar fences and their resistance to beta-thujaplicin. PubMed: Acaricidal activity of active constituent isolated in Chamaecyparis obtusa leaves against Dermatophagoides spp. PubMed: Protection by tropolones against H2O2-induced DNA damage and apoptosis in cultured Jurkat cells. PubMed: Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones. PubMed: Biological activity of beta-dolabrin, gamma-thujaplicin, and 4-acetyltropolone, hinokitiol-related compounds. PubMed: Biological activity of alpha-thujaplicin, the isomer of hinokitiol. PubMed: Cytotoxic activity of deferiprone, maltol and related hydroxyketones against human tumor cell lines. PubMed: (-)-Epigallocatechin-3-gallate and hinokitiol reduce melanin synthesis via decreased MITF production. PubMed: Jasmonate and ethylene signalling and their interaction are integral parts of the elicitor signalling pathway leading to beta-thujaplicin biosynthesis in Cupressus lusitanica cell cultures. PubMed: Beta-thujaplicin: new quantitative CZE method and adsorption to goethite. PubMed: Evaluation of developmental toxicity of beta-thujaplicin (hinokitiol) following oral administration during organogenesis in rats. PubMed: Rapid accumulation and metabolism of polyphosphoinositol and its possible role in phytoalexin biosynthesis in yeast elicitor-treated Cupressus lusitanica cell cultures. PubMed: Transmission electron microscopy of Schistosoma mansoni cercariae treated with hinokitiol (beta-thujaplicin), a compound for potential skin application against cercarial penetration. PubMed: [Antimicrobial activity of hinokitiol against Legionella pneumophila]. PubMed: Synthesis and structural characterization of silver(I), aluminium(III) and cobalt(II) complexes with 4-isopropyltropolone (hinokitiol) showing noteworthy biological activities. Action of silver(I)-oxygen bonding complexes on the antimicrobial activities. PubMed: Monoterpenes produced by Cupressus lusitanica cultured cells including a novel monoterpene (1R, 2S, 6S)-(+)-1,6-epoxy-4(8)-p-menthen-2-ol [corrected]. PubMed: Generation of reactive oxygen species from Hinokitiol under near-UV irradiation. PubMed: Multiple signalling pathways mediate fungal elicitor-induced beta-thujaplicin biosynthesis in Cupressus lusitanica cell cultures. PubMed: Antibacterial effect of beta-thujaplicin on staphylococci isolated from atopic dermatitis: relationship between changes in the number of viable bacterial cells and clinical improvement in an eczematous lesion of atopic dermatitis. PubMed: Biological activity of 4-acetyltropolone, the minor component of Thujopsis dolabrata SIeb. et Zucc. hondai Mak. PubMed: Feedback regulation of beta-thujaplicin production and formation of its methyl ether in a suspension culture of Cupressus lusitanica. PubMed: Fungicidal activity of beta-thujaplicin analogues. PubMed: Production of beta-thujaplicin in Cupressus lusitanica suspension cultures fed with organic acids and monoterpenes. PubMed: Biological activity of alpha-thujaplicin, the minor component of Thujopsis dolabrata SIEB. et ZUCC. var. hondai MAKINO. PubMed: Cytotoxic effects of beta-thujaplicin on rat thymocytes and prevention by the compound in tributyltin-induced thymocyte damage. PubMed: Improved beta-thujaplicin production in Cupressus lusitanica suspension cultures by fungal elicitor and methyl jasmonate. PubMed: Cytotoxicity of the hinokitiol-related compounds, gamma-thujaplicin and beta-dolabrin. PubMed: Identification of a compound in Chamaecyparis taiwanensis inhibiting the ice-nucleating activity of Pseudomonas fluorescens KUIN-1. PubMed: Hinokitiol, a selective inhibitor of the platelet-type isozyme of arachidonate 12-lipoxygenase. PubMed: Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities. PubMed: Phytogrowth-Inhibitory activities of beta-dolabrin and gamma-thujaplicin, hinokitiol-related compounds and constituents of Thujopsis dolabrata Sieb. et Zucc. var hondai Makino. PubMed: Apoptosis during iron chelator-induced differentiation in F9 embryonal carcinoma cells. PubMed: Teratogenicity of thujaplicin in ICR mice. PubMed: Antimicrobial activity and metalloprotease inhibition of hinokitiol-related compounds, the constituents of Thujopsis dolabrata S. and Z. hondai MAK. PubMed: Multi-enzymatic glucosylation using Eucalyptus UDP-glucosyltransferase coupled UDPglucose-fermentation by bakers' yeast. PubMed: Induction of apoptosis by hinokitiol, a potent iron chelator, in teratocarcinoma F9 cells is mediated through the activation of caspase-3. PubMed: Beta-thujaplicin zinc chelate induces apoptosis in mouse high metastatic melanoma B16BL6 cells. PubMed: Mechanism of mitochondrial dysfunction and cytotoxicity induced by tropolones in isolated rat hepatocytes. PubMed: Thujaplicin-copper chelates inhibit replication of human influenza viruses. PubMed: Effects of zinc oxide on the attachment of Staphylococcus aureus strains. PubMed: Inhibitory effect of beta-thujaplicin on ultraviolet B-induced apoptosis in mouse keratinocytes. PubMed: Biological activity of purpurogallin. PubMed: Induction of differentiation of embryonal carcinoma F9 cells by iron chelators. PubMed: Hinokitiol induces differentiation of teratocarcinoma F9 cells. PubMed: [On the antibacterial effect of hinokitiol against Staphylococcus aureus showing double zone phenomenon]. PubMed: Cytotoxic effect of hinokitiol and tropolone on the growth of mammalian cells and on blastogenesis of mouse splenic T cells. PubMed: [Study on the development of biological-active compounds after the model of natural products]. PubMed: High-performance liquid chromatographic determination of hinokitiol in cosmetics by the formation of difluoroborane compounds. PubMed: [A clinical re-evaluation of an Hinoporon on periodontal disease using the double blind method]. PubMed: [Methylation of hinokitiol and 7-iodohinokitiol and the syntheses of Schiff bases of hydrazinotropone derivatives and 5-aminohinokitiol]. PubMed: Calcium-independent release of [3H]dopamine by veratridine in pargyline- and reserpine-treated corpus striatum. PubMed: Allergic contact dermatitis to pyridoxine ester and hinokitiol. PubMed: The multifunctional actions of beta-thujaplicin on the oxidative energy transformations as a consequence of its lipophilic and chelating properties. PubMed: Comparison of the effects of tropolone, beta-thujaplicin and U-0521 on the extraneuronal accumulation of isoprenaline in guinea-pig trachealis smooth muscle cells. A quantitative fluorescence histochemical study. PubMed: The extraneuronal accumulation of isoprenaline in trachea and atria of guinea-pig and cat: a fluorescence histochemical study. PubMed: The uptake kinetics and metabolism of extraneuronal noradrenaline in guinea-pig trachea as studied with quantitative fluorescence microphotometry. PubMed: Antibacterial activity of beta-thujaplicin. PubMed: The effect of light on the antibacterial activity of beta-thujaplicin. PubMed: Synethesis of beta-dolabrin from beta-thujaplicin (hinokitiol). PubMed: Antibiotic substances from the heart wood of Thuja plicata D. Don; the constitution of beta-thujaplicin.