ferulenol

4H-1-benzopyran-4-one, 2-hydroxy-3-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]-

CAS: 6805-34-1 C24 H30 O3 MW: 366.50070000

Identification

Nameferulenol
IUPAC4-hydroxy-3-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]chromen-2-one
CAS Number6805-34-1
FDA UNIISearch
Molecular FormulaC24 H30 O3
Molecular Weight366.50070000
MDL NumberMFCD02183471
Nikkaji NumberJ128.596C

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 492.80 °C. @ 760.00 mm Hg (est)
Flash Point 323.00 °F. TCC ( 161.70 °C. ) (est)
logP (o/w) 7.730 (est)
Soluble in water, 0.001063 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for ferulenol usage levels up tonot for fragrance use.
Recommendation for ferulenol flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

4H-1- benzopyran-4-one, 2-hydroxy-3-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]- 4- hydroxy-3-(3,7,11-trimethyl-2,6,10-dodecatrienyl)-2H-1-benzopyran-2-one 4- hydroxy-3-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]chromen-2-one PubMed: Occurrence, elimination, and risk of anticoagulant rodenticides and drugs during wastewater treatment. PubMed: Chemical composition and in vitro activity of plant extracts from Ferula communis and Dittrichia viscosa against postharvest fungi. PubMed: Disruption of mitochondrial membrane potential by ferulenol and restoration by propolis extract: antiapoptotic role of propolis. PubMed: Characterization of anti-coagulant properties of prenylated coumarin ferulenol. PubMed: Ferulenol specifically inhibits succinate ubiquinone reductase at the level of the ubiquinone cycle. PubMed: Synthesis and structure-activity relationships of novel warfarin derivatives. PubMed: Antimycobacterial coumarins from the sardinian giant fennel (Ferula communis). PubMed: Antimycobacterial constituents from Juniperus procera, Ferula communis and Plumbago zeylanica and their in vitro synergistic activity with isonicotinic acid hydrazide. PubMed: HPLC-DAD-MS identification of bioactive secondary metabolites from Ferula communis roots. PubMed: Microtubule-interacting activity and cytotoxicity of the prenylated coumarin ferulenol. PubMed: Acute toxicity of ferulenol, a 4-hydroxycoumarin isolated from Ferula communis L. PubMed: Plasma ferulenol concentration and activity of clotting factors in sheep with Ferula communis variety brevifolia intoxication. PubMed: Ferula communis variety brevifolia intoxication of sheep. PubMed: Experimental studies on the toxicity of some compounds isolated from Ferula communis in the rat. PubMed: Experimental studies on the toxicity of Ferula communis in the rat. PubMed: Complex Acetylenes from the Roots of Ferula communis.