2-hydroxyacetaldehyde
acetaldehyde, 2-hydroxy-
Identification
| Name | 2-hydroxyacetaldehyde |
| IUPAC | 2-hydroxyacetaldehyde |
| CAS Number | 141-46-8 |
| EINECS | 205-484-9 |
| FDA UNII | W0A0XPU08U |
| Molecular Formula | C2 H4 O2 |
| Molecular Weight | 60.05228000 |
| MDL Number | MFCD00038088 |
| Nikkaji Number | J2.537B |
| Beilstein | 0506029 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 97.00 °C. @ 760.00 mm Hg |
| Boiling Point | 131.00 to 132.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 4.146000 mmHg @ 25.00 °C. (est) |
| Flash Point | 107.00 °F. TCC ( 41.67 °C. ) |
| logP (o/w) | -1.604 (est) |
| Soluble in | alcohol |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intraperitoneal-rat LD50 280 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for 2-hydroxyacetaldehyde usage levels up to | not for fragrance use. |
| Recommendation for 2-hydroxyacetaldehyde flavor usage levels up to | not for flavor use. |
BOC Sciences
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Potential Uses
Natural Occurrence
Synonyms
acetaldehyde, 2-hydroxy-
acetaldehyde, hydroxy-
diose
glycol aldehyde
glycolaldehyde
glycolic aldehyde
glycollaldehyde
hydroxyacetaldehyde
hydroxyethanal
2-
hydroxyethanal
methylol formaldehyde
mono-
methylol formaldehyde
methylolformaldehyde
PubMed:
Effects of chebulic acid on advanced glycation endproducts-induced collagen cross-links.
PubMed:
Roasting-induced changes in arabinotriose, a model of coffee arabinogalactan side chains.
PubMed:
[Ethylene glycol poisoning--the significance of analytical diagnosis based on reports from Wielkopolska].
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Small reactive carbonyl compounds as tissue lipid oxidation products; and the mechanisms of their formation thereby.
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Influence of phenolic compounds on the mechanisms of pyrazinium radical generation in the Maillard reaction.
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Anti-glycation effect of gold nanoparticles on collagen.
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Microbial oxidases catalyzing conversion of glycolaldehyde into glyoxal.
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Monocyte-endothelium-smooth muscle cell interaction in co-culture: proliferation and cytokine productions in response to advanced glycation end products.
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Lipid glycation and protein glycation in diabetes and atherosclerosis.
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Glycolaldehyde-modified β-lactoglobulin AGEs are unable to stimulate inflammatory signaling pathways in RAGE-expressing human cell lines.
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Model studies on chemical and textural modifications in gelatin films by reaction with glyoxal and glycolaldehyde.
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Synthesis of Passerini-Ugi hybrids by a four-component reaction using the glycolaldehyde dimer.
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FTIR monitoring of oxazolidin-5-one formation and decomposition in a glycolaldehyde-phenylalanine model system by isotope labeling techniques.
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Formation of furan and methylfuran by maillard-type reactions in model systems and food.
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Structure-reactivity relationships of flavan-3-ols on product generation in aqueous glucose/glycine model systems.
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Epicatechin carbonyl-trapping reactions in aqueous maillard systems: Identification and structural elucidation.
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Origin and mechanistic pathways of formation of the parent furan--a food toxicant.
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Formation of 3-hexuloses in aldol reactions, analysis of the products as their O-isopropylidene derivatives by GC-MS.
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Glyoxal/glycolaldehyde: a redox system involved in malolactic fermentation of wine.
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Chemical interactions between odor-active thiols and melanoidins involved in the aroma staling of coffee beverages.
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Amides are novel protein modifications formed by physiological sugars.
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Carbohydrate and amino acid degradation pathways in L-methionine/D-[13C] glucose model systems.
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Origin of carbohydrate degradation products in L-Alanine/D-[(13)C]glucose model systems.
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Formation of sugar-specific reactive intermediates from (13)C-labeled L-serines.
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Radical-assisted melanoidin formation during thermal processing of foods as well as under physiological conditions.
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Studies on radical intermediates in the early stage of the nonenzymatic browning reaction of carbohydrates and amino acids.
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Tetrahydro-beta-carboline carboxylic acids in smoked foods.
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Desmutagenic effect of alpha-dicarbonyl and alpha-hydroxycarbonyl compounds against mutagenic heterocyclic amines.
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The involvement of liver fructokinase in the metabolism of D-xylulose and xylitol in isolated rat hepatocytes.