platycodon grandiflorum root extract
extract of the roots of the fior palla, platycodon grandiflorum l., campanulaceae
Identification
| Name | platycodon grandiflorum root extract |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antioxidants |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | antioxidants |
| Recommendation for platycodon grandiflorum root extract usage levels up to | not for fragrance use. |
| Recommendation for platycodon grandiflorum root extract flavor usage levels up to | not for flavor use. |
Potential Uses
Natural Occurrence
Synonyms
extract of the roots of the fior palla, platycodon grandiflorum l., campanulaceae
PubMed:
Candidate Genes Involved in the Biosynthesis of Triterpenoid Saponins in Platycodon grandiflorum Identified by Transcriptome Analysis.
PubMed:
Platycodin D exerts anti-tumor efficacy in H22 tumor-bearing mice via improving immune function and inducing apoptosis.
PubMed:
Antiâinflammatory and antioxidant activity of the traditional herbal formula Gwakhyangjeonggiâsan via enhancement of heme oxygenaseâ1 expression in RAW264.7 macrophages.
PubMed:
[Effect of different nitrogen forms and ratio on growth and active ingredient content of Platycodon grandiflorum].
PubMed:
An integrated global chemomics and system biology approach to analyze the mechanisms of the traditional Chinese medicinal preparation Eriobotrya japonica - Fritillaria usuriensis dropping pills for pulmonary diseases.
PubMed:
Killing cancer with platycodin D through multiple mechanisms.
PubMed:
Pharmacokinetics, intestinal absorption and microbial metabolism of single platycodin D in comparison to Platycodi radix extract.
PubMed:
Global Profiling of Various Metabolites in Platycodon grandiflorum by UPLC-QTOF/MS.
PubMed:
Molecular marker development and genetic diversity exploration by RNA-seq in Platycodon grandiflorum.
PubMed:
[Effects of Ca2+ and SA on physiological and photosynthesis of Platycodon grandiflorum under high temperature stress].
PubMed:
Platycodon grandiflorum A. De Candolle Ethanolic Extract Inhibits Adipogenic Regulators in 3T3-L1 Cells and Induces Mitochondrial Biogenesis in Primary Brown Preadipocytes.
PubMed:
[Study on genetic polymorphism of Platycodon grandiflorum based on barcoding of ITS2].
PubMed:
Platycodin D Blocks Breast Cancer-Induced Bone Destruction by Inhibiting Osteoclastogenesis and the Growth of Breast Cancer Cells.
PubMed:
Platycodin-D Induced Autophagy in Non-Small Cell Lung Cancer Cells via PI3K/Akt/mTOR and MAPK Signaling Pathways.
PubMed:
Platycodin D attenuates acute lung injury by suppressing apoptosis and inflammation in vivo and in vitro.
PubMed:
Effects of Gancao on pharmacokinetic profiles of platycodin D and deapio-platycodin D in Jiegeng.
PubMed:
Platycodin D isolated from the aerial parts of Platycodon grandiflorum protects alcohol-induced liver injury in mice.
PubMed:
The inhibition of Platycodin D on Mycoplasma pneumoniae proliferation and its effect on promoting cell growth after anti-Mycoplasma pneumoniae treatment.
PubMed:
Dissipative particle dynamics study on self-assembled platycodin structures: the potential biocarriers for drug delivery.
PubMed:
Solubilization of menthol by platycodin D in aqueous solution: an integrated study of classical experiments and dissipative particle dynamics simulation.
PubMed:
Saponins, especially platyconic acid A, from Platycodon grandiflorum reduce airway inflammation in ovalbumin-induced mice and PMA-exposed A549 cells.
PubMed:
Pyrolytic and kinetic characteristics of Platycodon grandiflorum peel and its cellulose extract.
PubMed:
Root Rot of Balloon Flower (Platycodon grandiflorum) Caused by Fusarium solani and Fusarium oxysporum.
PubMed:
[Preparation of triterpene saponins from Platycodon grandiflorum by two-dimensional hydrophilic interaction liquid chromatography-reversed phase liquid chromatography].
PubMed:
Platycodin D inhibits tumor growth by antiangiogenic activity via blocking VEGFR2-mediated signaling pathway.
PubMed:
Assessment of Platycodon grandiflorum germplasm resources from northern Anhui province based on ISSR analysis.
PubMed:
Enhancement of chlorogenic acid production in hairy roots of Platycodon grandiflorum by over-expression of an Arabidopsis thaliana transcription factor AtPAP1.
PubMed:
Platycosides from the Roots of Platycodon grandiflorum and Their Health Benefits.
PubMed:
Platycodon grandiflorum polysaccharide induces dendritic cell maturation via TLR4 signaling.
PubMed:
Platycodon grandiflorum root-derived saponins attenuate atopic dermatitis-like skin lesions via suppression of NF-κB and STAT1 and activation of Nrf2/ARE-mediated heme oxygenase-1.
PubMed:
Determination of platycodin D and platycodin D3 in rat plasma using liquid chromatography-tandem mass spectrometry.
PubMed:
[Effect of fertilization levels on soil microorganism amount and soil enzyme activities].
PubMed:
Triterpenoid Saponins Isolated from Platycodon grandiflorum Inhibit Hepatitis C Virus Replication.
PubMed:
Saponins from the roots of Platycodon grandiflorum suppresses TGFβ1-induced epithelial-mesenchymal transition via repression of PI3K/Akt, ERK1/2 and Smad2/3 pathway in human lung carcinoma A549 cells.
PubMed:
Evaluation of the spermicidal and contraceptive activity of Platycodin D, a Saponin from Platycodon grandiflorum.
PubMed:
Effects of the root of Platycodon grandiflorum on airway mucin hypersecretion in vivo and platycodin D(3) and deapi-platycodin on production and secretion of airway mucin in vitro.
PubMed:
[Effects of promoting blood circulation to remove meridian obstruction combined with medicinal guides on related osteogenesis factors in rabbits with femoral head necrosis].
PubMed:
Platycodin D, a triterpenoid saponin from Platycodon grandiflorum, induces G2/M arrest and apoptosis in human hepatoma HepG2 cells by modulating the PI3K/Akt pathway.
PubMed:
[Isolation and identification of pathogen of seedling blight of Platycodon grandiflorum].
PubMed:
Platycodin D inhibits migration, invasion, and growth of MDA-MB-231 human breast cancer cells via suppression of EGFR-mediated Akt and MAPK pathways.
PubMed:
Saponins from Platycodon grandiflorum inhibit hepatic lipogenesis through induction of SIRT1 and activation of AMP-activated protein kinase in high-glucose-induced HepG2 cells.
PubMed:
Antiproliferative and apoptotic activities of triterpenoid saponins from the roots of Platycodon grandiflorum and their structure-activity relationships.
PubMed:
Crude saponins from Platycodon grandiflorum induce apoptotic cell death in RC-58T/h/SA#4 prostate cancer cells through the activation of caspase cascades and apoptosis-inducing factor.
PubMed:
Protective effect of the roots extract of Platycodon grandiflorum on bile duct ligation-induced hepatic fibrosis in rats.
PubMed:
Saponins, especially platycodin D, from Platycodon grandiflorum modulate hepatic lipogenesis in high-fat diet-fed rats and high glucose-exposed HepG2 cells.
PubMed:
Two new triterpenoid saponins from the root of Platycodon grandiflorum.
PubMed:
Enhanced accumulation of phytosterol and triterpene in hairy root cultures of Platycodon grandiflorum by overexpression of Panax ginseng 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
PubMed:
Platycodin D attenuates bile duct ligation-induced hepatic injury and fibrosis in mice.
PubMed:
Platycodon grandiflorus alleviates DNCB-induced atopy-like dermatitis in NC/Nga mice.
PubMed:
Development and characterization of 22 polymorphic microsatellite markers for the balloon flower Platycodon grandiflorum (Campanulaceae).
PubMed:
Protective effect of the aqueous extract from the root of Platycodon grandiflorum on cholestasis-induced hepatic injury in mice.
PubMed:
Hepatoprotective and anti-hepatitis C viral activity of Platycodon grandiflorum extract on carbon tetrachloride-induced acute hepatic injury in mice.
PubMed:
Improvement of atopic dermatitis-like skin lesions by Platycodon grandiflorum fermented by Lactobacillus plantarum in NC/Nga mice.
PubMed:
Anti-atherosclerotic activity of platycodin D derived from roots of Platycodon grandiflorum in human endothelial cells.
PubMed:
Long-Term Consumption of Platycodi Radix Ameliorates Obesity and Insulin Resistance via the Activation of AMPK Pathways.
PubMed:
Platycodin D induces reactive oxygen species-mediated apoptosis signal-regulating kinase 1 activation and endoplasmic reticulum stress response in human breast cancer cells.
PubMed:
Platycodon grandiflorum root attenuates vascular endothelial cell injury by oxidized low-density lipoprotein and prevents high-fat diet-induced dyslipidemia in mice by up-regulating antioxidant proteins.
PubMed:
Platycodin D, a triterpenoid sapoinin from Platycodon grandiflorum, ameliorates cisplatin-induced nephrotoxicity in mice.
PubMed:
Evaluation of the total oxidant scavenging capacity of saponins isolated from Platycodon grandiflorum.
PubMed:
[The performance of agronomic traits in F1 crossing combinations derived from male sterile line of Platycodon grandiflorum].
PubMed:
Platycodon grandiflorum modifies adipokines and the glucose uptake in high-fat diet in mice and L6 muscle cells.
PubMed:
Protective Effects of Platycodon grandiflorum Aqueous Extract on Thioacetamide-induced Fulminant Hepatic Failure in Mice.
PubMed:
Characterization and quantification of major constituents of Xue Fu Zhu Yu by UPLC-DAD-MS/MS.
PubMed:
Two new oleanane-type triterpenoids from Platycodi Radix and anti-proliferative activity in HSC-T6 cells.
PubMed:
Single oral dose toxicity test of platycodin d, a saponin from platycodin radix in mice.
PubMed:
A sensitive method for determination of platycodin d in rat plasma using liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study.
PubMed:
[Study on industrialization production technology of decoction pieces shuangfei of Platycodon grandiflorum].
PubMed:
[Preliminary study on the effect of climate factors on pollen fertility in Platycodon grandiflorum].
PubMed:
Saponins from the roots of Platycodon grandiflorum suppress ultraviolet A-induced matrix metalloproteinase-1 expression via MAPKs and NF-κB/AP-1-dependent signaling in HaCaT cells.
PubMed:
Structure-function relationship of the saponins from the roots of Platycodon grandiflorum for hemolytic and adjuvant activity.
PubMed:
Preparative separation of minor saponins from Platycodi Radix by high-speed counter-current chromatography.
PubMed:
Hepatoprotective effect of Platycodon grandiflorum against chronic ethanol-induced oxidative stress in C57BL/6 mice.
PubMed:
WNT/β-catenin pathway mediates the anti-adipogenic effect of platycodin D, a natural compound found in Platycodon grandiflorum.
PubMed:
A homogalacturonan from the radix of Platycodon grandiflorum and the anti-angiogenesis activity of poly-/oligogalacturonic acids derived therefrom.
PubMed:
Screening and appraisal for immunological adjuvant-active fractions from Platycodon grandiflorum total saponins.
PubMed:
Inhibition of acrolein-stimulated MUC5AC expression by Platycodon grandiflorum root-derived saponin in A549 cells.
PubMed:
Platycoside O, a new triterpenoid saponin from the roots of Platycodon grandiflorum.
PubMed:
[Experimental study on anti-influenza virus infection with yinqiao-decoction by orthogonal design].
PubMed:
Effects of dietary supplementation of Chinese medicinal herbs on polymorphonuclear neutrophil immune activity and small intestinal morphology in weanling pigs.
PubMed:
[Effect of seed soaking with aluminum on seed germination and seedling physiology of Platycodon grandiflorum].
PubMed:
[Heterosis analysis of the main agronomic characters of Platycodon grandiflorum].
PubMed:
[Effects of applying controlled-release compound fertilizer on Platycodon grandiflorum growth].
PubMed:
[Mechanism for sperm immobilization activity of extract from Platycodon grandiflorum in vitro].
PubMed:
Inhibitory effect of Platycodon grandiflorum on T(H)1 and T(H)2 immune responses in a murine model of 2,4-dinitrofluorobenzene-induced atopic dermatitis-like skin lesions.
PubMed:
The neuroprotective effect of modified Yeoldahanso-tang via autophagy enhancement in models of Parkinson's disease.
PubMed:
Platycoside N: a new oleanane-type triterpenoid saponin from the roots of Platycodon grandiflorum.
PubMed:
An efficient protocol for genetic transformation of Platycodon grandiflorum with Agrobacterium rhizogenes.
PubMed:
Antiproliferative effects of saponins from the roots of Platycodon grandiflorum on cultured human tumor cells.
PubMed:
Structural characterization of an arabinogalactan from Platycodon grandiflorum roots and antiangiogenic activity of its sulfated derivative.
PubMed:
Saponins from the roots of Platycodon grandiflorum stimulate osteoblast differentiation via p38 MAPK- and ERK-dependent RUNX2 activation.
PubMed:
Anti-allergic activity of a platycodon root ethanol extract.
PubMed:
Constituents of the flowers of Platycodon grandiflorum with inhibitory activity on advanced glycation end products and rat lens aldose reductase in vitro.
PubMed:
Mucilaginibacter dorajii sp. nov., isolated from the rhizosphere of Platycodon grandiflorum.
PubMed:
Enzymatic transformation of platycosides and one-step separation of platycodin D by high-speed countercurrent chromatography.
PubMed:
Ethanol extract and saponin of Platycodon grandiflorum ameliorate scopolamine-induced amnesia in mice.
PubMed:
Platycodin D induces apoptosis in MCF-7 human breast cancer cells.
PubMed:
Platycodon grandiflorum induces apoptosis in SKOV3 human ovarian cancer cells through mitochondrial-dependent pathway.
PubMed:
Platycodin d improves the immunogenicity of newcastle disease virus-based recombinant avian influenza vaccine in mice.
PubMed:
Molecular mechanism of endothelial nitric-oxide synthase activation by Platycodon grandiflorum root-derived saponins.
PubMed:
Effect of plant age on endophytic bacterial diversity of balloon flower (Platycodon grandiflorum) root and their antimicrobial activities.
PubMed:
Preventative effects of Platycodon grandiflorum treatment on hepatic steatosis in high fat diet-fed C57BL/6 mice.
PubMed:
The effects of the Chinese herbal medicine EMF01 on salicylate-induced tinnitus in rats.
PubMed:
Platycodin D2 improves specific cellular and humoral responses to hepatitis B surface antigen in mice.
PubMed:
[Effect of chlorpromazine combined with Platycodon grandiflorum on change of dopamine in rat striatum by microdialysis].
PubMed:
A study on the antioxidant activity and tissues selective inhibition of lipid peroxidation by saponins from the roots of Platycodon grandiflorum.
PubMed:
Evaluation of the phototoxic potential of plants used in oriental medicine.
PubMed:
Protective effects of saponins from the root of Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the activation of AMP-dependent protein kinase.
PubMed:
NF-kappaB Activation by compounds found in Platycodon grandiflorum extract.
PubMed:
Platycodin D and 2''-O-acetyl-polygalacin D2 isolated from Platycodon grandiflorum protect ischemia/reperfusion injury in the gerbil hippocampus.
PubMed:
Inhibitory mechanism of saponins derived from roots of Platycodon grandiflorum on anaphylactic reaction and IgE-mediated allergic response in mast cells.
PubMed:
[Dynamic research of density on Platycodon grandiflorum dry material accumulation and platycodin D content in Platycodon grandiflorum].
PubMed:
[Measurement and analysis of platycodon grandiflorum with space flight mutagenesis breeding by XRF].
PubMed:
Saponins isolated from the root of Platycodon grandiflorum protect against acute ethanol-induced hepatotoxicity in mice.
PubMed:
[Study on spaceflight mutagenesis Platycodon grandiflorum via FTIR].
PubMed:
Platycodin D is a potent adjuvant of specific cellular and humoral immune responses against recombinant hepatitis B antigen.
PubMed:
Hypocholesterolemic and anti-obesity effects of saponins from Platycodon grandiflorum in hamsters fed atherogenic diets.
PubMed:
Platyconic acid A, a genuine triterpenoid saponin from the roots of Platycodon grandiflorum.
PubMed:
[Effects of top pruning on fruiting characters of Platycodon grandiflorum].
PubMed:
Induction of apoptosis in HT-29 colon cancer cells by crude saponin from Platycodi Radix.
PubMed:
Implication of intracellular ROS formation, caspase-3 activation and Egr-1 induction in platycodon D-induced apoptosis of U937 human leukemia cells.
PubMed:
Lead compounds for anti-inflammatory drugs isolated from the plants of the traditional oriental medicine in Korea.
PubMed:
Induction of cell proliferation and neuroblasts in the subgranular zone of the dentate gyrus by aqueous extract from Platycodon grandiflorum in middle-aged mice.
PubMed:
Platycodin D2 is a potential less hemolytic saponin adjuvant eliciting Th1 and Th2 immune responses.
PubMed:
A promising balanced Th1 and Th2 directing immunological adjuvant, saponins from the root of Platycodon grandiflorum.
PubMed:
Ameliorating effect of balloon flower saponin on the ethanol-induced memory impairment in mice.
PubMed:
Contribution of the glycidic moieties to the haemolytic and adjuvant activity of platycodigenin-type saponins from the root of Platycodon grandiflorum.
PubMed:
Saponins derived from the roots of Platycodon grandiflorum inhibit HT-1080 cell invasion and MMPs activities: regulation of NF-kappaB activation via ROS signal pathway.
PubMed:
Platycodin D induces mitotic arrest in vitro, leading to endoreduplication, inhibition of proliferation and apoptosis in leukemia cells.
PubMed:
Protective effect of saponins derived from the roots of Platycodon grandiflorum against carbon tetrachloride induced hepatotoxicity in mice.
PubMed:
[Effects of Salviae miltiorrhizae and Platycodon grandiflorum in Tianwang Buxin decoction for microcirculation of brain meninx vascullosa in rats].
PubMed:
Platycodin D induces apoptosis and decreases telomerase activity in human leukemia cells.
PubMed:
[Observation of pollen tube germination of Platycodon grandiflorum by fluorescence microscopy].
PubMed:
Enzymatic modification of saponins from Platycodon grandiflorum with Aspergillus niger.
PubMed:
Cytotoxic triterpenoid saponins from the roots of Platycodon grandiflorum.
PubMed:
Platycodon grandiflorum extract represses up-regulated adipocyte fatty acid binding protein triggered by a high fat feeding in obese rats.
PubMed:
[Effect compound decoction on notoginsenosides in Panax notoginseng].
PubMed:
Antioxidant and antimicrobial capacity of Chinese medicinal herb extracts in raw sheep meat.
PubMed:
Protective effects of Platycodi radix on alcohol-induced fatty liver.
PubMed:
[Relative adscriptions of components in the effective fractions of Yinqiao decoction and its composing individual herbs].
PubMed:
[Study on seed quality test and quality standard of Platycodon grandiflorum].
PubMed:
[Advances in studies on Platycodon grandiflorum].
PubMed:
Triterpenoid saponins from Platycodon grandiflurum.
PubMed:
Antihyperglycemic effects of Platycodon grandiflorum (Jacq.) A. DC. extract on streptozotocin-induced diabetic mice.
PubMed:
7-Polyacylated delphinidin 3,7-diglucosides from the blue flowers of Leschenaultia cv. Violet Lena.
PubMed:
[Chemical constituents from roots of Platycodon grandiflorum].
PubMed:
Authentication of traditional Chinese medicine using infrared spectroscopy: distinguishing between ginseng and its morphological fakes.
PubMed:
[Influence of exogenous substance on germination of Platycodon grandiflorum seeds].
PubMed:
[Studies on germination characteristics of Platycodon grandiflorum seed].
PubMed:
[Inhibitory effects of natural plant extracts on Verticillium albo-atrum].
PubMed:
Chemopreventive effect of saponins derived from roots of Platycodon grandiflorum on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in A/J mice.
PubMed:
New A-ring lactone triterpenoid saponins from the roots of Platycodon grandiflorum.
PubMed:
Inhibition of tumor invasion and metastasis by aqueous extract of the radix of Platycodon grandiflorum.
PubMed:
[Saponins of polygalacic acid type from Platycodon grandiflorum].
PubMed:
Effects of Platycodon grandiflorum on lipopolysaccharide-stimulated production of prostaglandin E2, nitric oxide, and interleukin-8 in mouse microglial BV2 cells.
PubMed:
[Study on the stigma/pollen vigor and self-compatibility of Platycodon grandiflorum].
PubMed:
Inhibitory effect of the saponins derived from roots of Platycodon grandiflorum on carrageenan-induced inflammation.
PubMed:
Platycodin D-induced apoptosis through nuclear factor-kappaB activation in immortalized keratinocytes.
PubMed:
Five new triterpenoid saponins from the roots of Platycodon grandiflorum.
PubMed:
Determination of organophosphorus pesticide residues in the roots of Platycodon grandiflorum by solid-phase extraction and gas chromatography with flame photometric detection.
PubMed:
Prostaglandin-H-synthase (PGHS)-1 and -2 microtiter assays for the testing of herbal drugs and in vitro inhibition of PGHS-isoenzyms by polyunsaturated fatty acids from Platycodi radix.
PubMed:
Inhibition of tumor necrosis factor-alpha-induced expression of adhesion molecules in human endothelial cells by the saponins derived from roots of Platycodon grandiflorum.
PubMed:
[Determination of organochlorine pesticide residues in nine herbs by solid-phase extraction and capillary gas chromatography].
PubMed:
Biotransformation of alpha-santonin by cell suspension cultures of five plants.
PubMed:
Isolation of a new saponin and cytotoxic effect of saponins from the root of Platycodon grandiflorum on human tumor cell lines.
PubMed:
Induction of apoptosis and inhibition of telomerase activity by aqueous extract from Platycodon grandiflorum in human lung carcinoma cells.
PubMed:
Inhibition of inducible nitric oxide synthase and cyclooxygenase II by Platycodon grandiflorum saponins via suppression of nuclear factor-kappaB activation in RAW 264.7 cells.
PubMed:
Suppressive effects of Platycodon grandiflorum on the progress of carbon tetrachloride-induced hepatic fibrosis.
PubMed:
Antioxidant activity of phenylpropanoid esters isolated and identified from Platycodon grandiflorum A. DC.
PubMed:
Polyphenolic compounds from Platycodon grandiflorum A. DC.
PubMed:
Activation of mitogen-activated protein kinases and AP-1 by polysaccharide isolated from the radix of Platycodon grandiflorum in RAW 264.7 cells.
PubMed:
Antinociceptive profiles of platycodin D in the mouse.
PubMed:
Antioxidant and anticancer activities of organic extracts from Platycodon grandiflorum A. De Candolle roots.
PubMed:
Platycodin D and D3 isolated from the root of Platycodon grandiflorum modulate the production of nitric oxide and secretion of TNF-alpha in activated RAW 264.7 cells.
PubMed:
Protective effect of saponins derived from roots of Platycodon grandiflorum on tert-butyl hydroperoxide-induced oxidative hepatotoxicity.
PubMed:
Toll-like receptor 4-dependent activation of macrophages by polysaccharide isolated from the radix of Platycodon grandiflorum.
PubMed:
Endophytic colonization of balloon flower by antifungal strain Bacillus sp. CY22.
PubMed:
[Evaluations of saponin properties of HPLC analysis of Platycodon grandiflorum A.DC].
PubMed:
Biotransformation of 4(20),11-taxadienes by cell suspension cultures of Platycodon grandiflorum.
PubMed:
[Induction and identification of autotetraploid plant of Platycodon grandiflorum].
PubMed:
[Ultrastructural changes after space flight in Platycodon grandiflorum (Jacq.) DC].
PubMed:
Endophytic bacillus sp. isolated from the interior of balloon flower root.
PubMed:
Platycodin D and D3 increase airway mucin release in vivo and in vitro in rats and hamsters.
PubMed:
Protective effect of Platycodi radix on carbon tetrachloride-induced hepatotoxicity.
PubMed:
Hepatoprotective effects of Platycodon grandiflorum on acetaminophen-induced liver damage in mice.
PubMed:
Polysaccharide isolated from the radix of Platycodon grandiflorum selectively activates B cells and macrophages but not T cells.
PubMed:
Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum.
PubMed:
Aqueous extract isolated from Platycodon grandiflorum elicits the release of nitric oxide and tumor necrosis factor-alpha from murine macrophages.
PubMed:
Augmentation of macrophage functions by an aqueous extract isolated from Platycodon grandiflorum.
PubMed:
Effect of dietary Platycodon grandiflorum on the improvement of insulin resistance in obese Zucker rats.
PubMed:
A comparative study on commercial, botanical gardens and wild samples of the roots of Platycodon grandiflorum by HPLC analysis.
PubMed:
Two new triterpenoid saponins from Platycodon grandiflorum.
PubMed:
Stimulative effects of saponin from kikyo-to, a Japanese herbal medicine, on pancreatic exocrine secretion of conscious rats.
PubMed:
[Comparative study on the erect and fallen types of Platycodon grandiflorum (Jacq.) DC].
PubMed:
Effects of Platycodon grandiflorum feeding on serum and liver lipid concentrations in rats with diet-induced hyperlipidemia.
PubMed:
[Studies on the medicinal plant in the "Sambutsu-cho" of Higo Province possessed by the Kumamoto clan (II): on the medicina herbs].
PubMed:
Studies on the conformational aspects of inulin oligomers.
PubMed:
A study on the mutagenicity of 102 raw pharmaceuticals used in Chinese traditional medicine.
PubMed:
[Cultivation of Platycodon grandiflorum].
PubMed:
[Rat plasma corticosterone secretion-inducing activities of total saponin and prosapogenin methyl esters from the roots of Platycodon grandiflorum A.DC].
PubMed:
Screening of the wormicidal Chinese raw drugs on Clonorchis sinensis.
PubMed:
Studies on the saponins of the root of Platycodon grandiflorum A. De Candolle. I. Isolation and the structure of platycodin-D.
PubMed:
[Pharmacological studies on Platycodon grandiflorum A. DC. IV. A comparison of experimental pharmacological effects of crude platycodin with clinical indications of platycodi radix (author's transl)].
PubMed:
[Pharmacological studies on Platycodon grandiflorum A. DC. 3. Activities of crude platycodin on respiratory and circulatory systems and its other pharmacological activities].
PubMed:
[Pharmacological studies on Platycodon grandiflorum A. DC. II. Anti-inflammatory activity of crude platycodin, its activities on isolated organs and other pharmacological activities].
PubMed:
[Pharmacological studies on Platycodon grandiflorum A. DC. I. Acute toxicity and central depressant activity of crude platycodin].