menthyl acetate

cyclohexanol, 5-methyl-2-(1-methylethyl)-, acetate, (1R,2S,5R)-

CAS: 89-48-5 C12 H22 O2 MW: 198.30574000 mentholic cooling

Identification

Namementhyl acetate
IUPAC[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl] acetate
CAS Number89-48-5
EINECS201-911-8
FDA UNIILF3LEI45OH
Molecular FormulaC12 H22 O2
Molecular Weight198.30574000
MDL NumberMFCD00062975
Nikkaji NumberJ71.002D
CoE Number206

Regulatory

FEMA Number2668
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)89-48-5 ; MENTHYL ACETATE
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance colorless clear liquid (est)
Assay 97.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 0.91800 to 0.92500 @ 25.00 °C.
Pounds per Gallon - (est). 7.639 to 7.697
Refractive Index 1.43990 to 1.44900 @ 20.00 °C.
Melting Point 23.00 to 24.00 °C. @ 760.00 mm Hg
Boiling Point 228.00 to 229.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.071000 mmHg @ 25.00 °C. (est)
Flash Point 198.00 °F. TCC ( 92.22 °C. )
logP (o/w) 4.182 (est)
Soluble in alcohol
Insoluble in water

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesfragrance

Organoleptic Properties

Odor Description
at 100.00 %.
Tea-like, slightly cooling, minty and fruity
Taste Description at 10.00 ppm.

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for menthyl acetate usage levels up to4.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)270.00 (μg/capita/day)
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

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Potential Uses

FR peppermint

Natural Occurrence

cornmint leaf cornmint oil india @ 6.11% Data cornmint plant horsemint plant melissa oil slovak republic @ 0.27% Data mint plant peppermint leaf peppermint oil america @ 3.69% Data peppermint oil CO2 extract @ 11.70% Data peppermint oil mongolia @ 9.39% Data peppermint oil russia @ 3.75% Data water mint leaf water mint shoot

Synonyms

cyclohexanol, 5-methyl-2-(1-methylethyl)-, acetate, (1R,2S,5R)- p- menth-3-yl acetate, dl- para- menth-3-yl acetate, dl- p- menthan-3-yl acetate, dl- para- menthan-3-yl acetate, dl- menthol acetate (-)- menthol acetate menthol, acetate, (1R,3R,4S)-(-)- menthyl acetate natural 5- methyl-2-(1-methyl ethyl) cyclohexanol acetate 5- methyl-2-(1-methylethyl)cyclohexanol acetate [(1R,2S,5R)-5- methyl-2-propan-2-ylcyclohexyl] acetate (1alpha, 2beta, 5alpha)-2-iso propyl-5-methylcyclohexyl acetate (1R,2S,5R)-2-iso propyl-5-methylcyclohexyl acetate (1R,2S,5R)-rel-2-iso propyl-5-methylcyclohexyl acetate PubMed: Peppermint (Mentha piperita) and albendazole against anisakiasis in an animal model. PubMed: Seasonal variability of the main components in essential oil of Mentha × piperita L. PubMed: Biocontrol potential of essential oil monoterpenes against housefly, Musca domestica (Diptera: Muscidae). PubMed: Biochemical studies on a versatile esterase that is most catalytically active with polyaromatic esters. PubMed: Structure-activity relationships of monoterpenes and acetyl derivatives against Aedes aegypti (Diptera: Culicidae) larvae. PubMed: Chemical Composition, Antifungal and Antibiofilm Activities of the Essential Oil of Mentha piperita L. PubMed: Volatile oil constituents of different parts of Artemisia chamaemelifolia and the composition and antibacterial activity of the aerial parts of A. turcomanica from Iran. PubMed: Antioxidant and antibacterial effects of Lavandula and Mentha essential oils in minced beef inoculated with E. coli O157:H7 and S. aureus during storage at abuse refrigeration temperature. PubMed: Composition of seed essential oils of Rhododendron tomentosum. PubMed: Development of quality assessment method for optically active food flavor chemicals. PubMed: Peppermint oil decreases the production of virulence-associated exoproteins by Staphylococcus aureus. PubMed: An efficient bioprocess for enzymatic production of L-menthol with high ratio of substrate to catalyst using whole cells of recombinant E. coli. PubMed: Chemical composition, olfactory evaluation and antioxidant effects of essential oil from Mentha x piperita. PubMed: Toxicity to vapor exposure and topical application of essential oils and monoterpenes on Musca domestica (Diptera: Muscidae). PubMed: Fumigant insecticidal activity and repellent effect of five essential oils and seven monoterpenes on first-instar nymphs of Rhodnius prolixus. PubMed: Biotransformation of menthol and geraniol by hairy root cultures of Anethum graveolens: effect on growth and volatile components. PubMed: Chemical composition of essential oils of Thymus and Mentha species and their antifungal activities. PubMed: Comparative analysis of some active principles of herb plants by GC/MS. PubMed: Enhancement in skin permeation of 5-aminolevulinic acid using l-menthol and its derivatives. PubMed: Insecticidal activity of menthol derivatives against mosquitoes. PubMed: Lithium amide assisted asymmetric Mannich-type reactions of menthyl acetate with PMP-aldimines. PubMed: Lytic activity of l-menthol derivatives against the snow blight disease fungus, Micronectriella nivalis. PubMed: Esterases from Bacillus subtilis and B. stearothermophilus share high sequence homology but differ substantially in their properties. PubMed: Evaluation of peppermint oil and ascorbyl palmitate as inhibitors of cytochrome P4503A4 activity in vitro and in vivo. PubMed: Effect of Mentha x piperita essential oil and monoterpenes on cucumber root membrane potential. PubMed: Ambulation-promoting effect of peppermint oil and identification of its active constituents. PubMed: Monoterpene composition of essential oil from peppermint (Mentha x piperita L.) with regard to leaf position using solid-phase microextraction and gas chromatography/mass spectrometry analysis. PubMed: Constituents of Essential Oils from Mentha X rotundifolia Growing Wild in Greece. PubMed: Chemical and Morphometrical Comparison Between two Peppermint Notomorphs. PubMed: Metabolism of Monoterpenes : Early Steps in the Metabolism of d-Neomenthyl-beta-d-Glucoside in Peppermint (Mentha piperita) Rhizomes. PubMed: Metabolism of Monoterpenes: Conversion of l-Menthone to l-Menthol and d-Neomenthol by Stereospecific Dehydrogenases from Peppermint (Mentha piperita) Leaves. PubMed: Demonstration of the Intercellular Compartmentation of l-Menthone Metabolism in Peppermint (Mentha piperita) Leaves. PubMed: Metabolism of Monoterpenes : EVIDENCE FOR COMPARTMENTATION OF l-MENTHONE METABOLISM IN PEPPERMINT (MENTHA PIPERITA) LEAVES. PubMed: Metabolism of Monoterpenes: Acetylation of (-)-Menthol by a Soluble Enzyme Preparation from Peppermint (Mentha piperita) Leaves. PubMed: Genetic basis for high limonene-cineole content of exceptional Mentha citrata hybrids. PubMed: The liquid-liquid counter current separation of a menthol-menthyl acetate mixture. PubMed: A note on the preparation of 1-menthyl acetate.