riboflavin tetrabutyrate

riboflavin, 2',3',4',5'-tetrabutanoate

CAS: 752-56-7 C33 H44 N4 O10 MW: 656.73368000

Identification

Nameriboflavin tetrabutyrate
IUPAC[(2R,3S,4S)-2,3,4-tri(butanoyloxy)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)pentyl] butanoate
CAS Number752-56-7
EINECS212-034-5
FDA UNIIF211C9MSGY
Molecular FormulaC33 H44 N4 O10
Molecular Weight656.73368000
Nikkaji NumberJ53.500A

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 0.002018 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin conditioning

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic ingredient for skin conditioning
Recommendation for riboflavin tetrabutyrate usage levels up tonot for fragrance use.
Recommendation for riboflavin tetrabutyrate flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

D- ribitol, 1-deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-, 2,3,4,5-tetrabutanoate riboflavin, 2',3',4',5'-tetrabutanoate 2,3,4,5- tetra-O-butyryl-1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-D-ribitol [(2R,3S,4S)-2,3,4- tri(butanoyloxy)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)pentyl] butanoate PubMed: Highly versatile nanohydrogel platform based on riboflavin-polysaccharide derivatives useful in the development of intrinsically fluorescent and cytocompatible drug carriers. PubMed: Different cell death mechanisms are induced by a hydrophobic flavin in human tumor cells after visible light irradiation. PubMed: [Structures of riboflavin tetraacetate and tetrabutyrate. II. Stacking interaction]. PubMed: Synthesis and pharmacological study of antihyperlipaemic activity of 2-substituted thieno(2,3-d)pyrimidin-4(3H)-ones. PubMed: [Effects of riboflavin tetrabutyrate (RTB) on plasma lipids, platelet aggregation and plasmin activity in rats]. PubMed: [Studies on color and chemical structure in the solid state of riboflavin tetrabutyrate]. PubMed: Effects of riboflavin-2', 3', 4', 5'-tetrabutyrate on platelet function and plasma lipids. PubMed: [Clinical studies on serum lipids in the patients with tumor of the prostate gland. 3rd report: changes of serum lipid peroxide levels during estrogen therapy for prostatic cancer and therapeutic and preventive effect of riboflavin tetrabutylate for hyperlipidemia]. PubMed: Effect of chronic administration of riboflavin 2',3',4',5'-tetrabutyrate on the hepatic enzymes of fatty acid oxidation in the rat. PubMed: Hydroxylation of the 7- and 8-methyl groups of riboflavin by the microsomal electron transfer system of rat liver. PubMed: [Spectral characteristics of riboflavin tetrabutyrate]. PubMed: Effect of vitamin B2 on tumorigenesis of 3-methylcholanthrene in the mouse skin. PubMed: Anti-oxidative effects of vitamin B2-butyrate on the cardiac mitochondrial disorders induced by adriamycin. PubMed: [Biochemical and histological studies on the exposure with concentrated oxygen. Special attention to the generation of peroxidized lipids (author's transl)]. PubMed: [Effects of vitamin B2-deficiency and B2-butyrate feeding on rat liver microsomes (author's transl)]. PubMed: Effect of hydrogen bonding on electronic spectra and reactivity of flavins. PubMed: Rat brain homogenate for in vitro evaluation of anti-lipoperoxide activity of riboflavin tetrabutyrate. PubMed: The effect of riboflavin tetrabutyrate on lipoperoxide content of oils and experimental hyperlipaemia on rats and rabbits and its comparison with clofibrate. PubMed: Nitrogen-15 and carbon-13 nuclear magnetic resonance of reduced flavins. Comparative study with oxidized flavins. PubMed: Urinary and serum flavin levels after a single dose of riboflavin or riboflavin tetrabutyrate in man. PubMed: Serum flavin levels and urinary excretion of riboflavin and riboflavin tetrabutyrate--a comparative evaluation. PubMed: Studies on the effect of riboflavin tetrabutyrate on the atherosclerosis induced by cholesterol feeding in rabbits. II. Effect of riboflavin tetrabutyrate on the formation of atherosclerosis. PubMed: Studies on the effect of riboflavin tetrabutyrate on the atherosclerosis induced by cholesterol feeding in rabbits. I. Effect of riboflavin tetrabutyrate on serum and hepatic lipids. PubMed: Crystalline molecular complex of riboflavin tetrabutyrate and N,N-dimethyl-4-aminoazobenzene. PubMed: Effect of riboflavin tetrabutyrate on degradation of -lipoprotein by fatty acid peroxide. PubMed: Studies on fatty acid esters of flavins. 8. Mechanism of hydrolysis of riboflavin tetrabutyrate by pancreatic lipase. PubMed: Studies on fatty acid esters of flavins. VII. Reaction of riboflavin tetrabutyrate with linoleic acid under ultra violet light irradiation. PubMed: Direct absorption of riboflavin tetrabutyrate through digestive canal. PubMed: Studies on fatty acid esters of flavins. VI. Incorporation of riboflavin part of riboflavin tetrabutyrate-2-14C into flavin nucleotides in the organs of rat. PubMed: [Studies on riboflavin tetrabutyrate (B2-But) and its effects on p-dimethylaminoazobenzene (DAB) induced hepatoma or degenerated liver of the rat; ESR spectra of the subfraction of lipoperoxide extracted from the liver and several enzyme activities of the same tissue]. PubMed: [Studies on heterocyclic compounds. VII. Electronic properties of riboflavin. (1). Electronic spectra of isoalloxazine core. Observation with nonaqueous solutions of riboflavin tetrabutyrate]. PubMed: Absorption and fluorescence spectra of riboflavin tetrabutyrate in various solvents.