riboflavin tetrabutyrate
riboflavin, 2',3',4',5'-tetrabutanoate
Identification
| Name | riboflavin tetrabutyrate |
| IUPAC | [(2R,3S,4S)-2,3,4-tri(butanoyloxy)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)pentyl] butanoate |
| CAS Number | 752-56-7 |
| EINECS | 212-034-5 |
| FDA UNII | F211C9MSGY |
| Molecular Formula | C33 H44 N4 O10 |
| Molecular Weight | 656.73368000 |
| Nikkaji Number | J53.500A |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 0.002018 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic ingredient for skin conditioning |
| Recommendation for riboflavin tetrabutyrate usage levels up to | not for fragrance use. |
| Recommendation for riboflavin tetrabutyrate flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
D-
ribitol, 1-deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-, 2,3,4,5-tetrabutanoate
riboflavin, 2',3',4',5'-tetrabutanoate
2,3,4,5-
tetra-O-butyryl-1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-D-ribitol
[(2R,3S,4S)-2,3,4-
tri(butanoyloxy)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)pentyl] butanoate
PubMed:
Highly versatile nanohydrogel platform based on riboflavin-polysaccharide derivatives useful in the development of intrinsically fluorescent and cytocompatible drug carriers.
PubMed:
Different cell death mechanisms are induced by a hydrophobic flavin in human tumor cells after visible light irradiation.
PubMed:
[Structures of riboflavin tetraacetate and tetrabutyrate. II. Stacking interaction].
PubMed:
Synthesis and pharmacological study of antihyperlipaemic activity of 2-substituted thieno(2,3-d)pyrimidin-4(3H)-ones.
PubMed:
[Effects of riboflavin tetrabutyrate (RTB) on plasma lipids, platelet aggregation and plasmin activity in rats].
PubMed:
[Studies on color and chemical structure in the solid state of riboflavin tetrabutyrate].
PubMed:
Effects of riboflavin-2', 3', 4', 5'-tetrabutyrate on platelet function and plasma lipids.
PubMed:
[Clinical studies on serum lipids in the patients with tumor of the prostate gland. 3rd report: changes of serum lipid peroxide levels during estrogen therapy for prostatic cancer and therapeutic and preventive effect of riboflavin tetrabutylate for hyperlipidemia].
PubMed:
Effect of chronic administration of riboflavin 2',3',4',5'-tetrabutyrate on the hepatic enzymes of fatty acid oxidation in the rat.
PubMed:
Hydroxylation of the 7- and 8-methyl groups of riboflavin by the microsomal electron transfer system of rat liver.
PubMed:
[Spectral characteristics of riboflavin tetrabutyrate].
PubMed:
Effect of vitamin B2 on tumorigenesis of 3-methylcholanthrene in the mouse skin.
PubMed:
Anti-oxidative effects of vitamin B2-butyrate on the cardiac mitochondrial disorders induced by adriamycin.
PubMed:
[Biochemical and histological studies on the exposure with concentrated oxygen. Special attention to the generation of peroxidized lipids (author's transl)].
PubMed:
[Effects of vitamin B2-deficiency and B2-butyrate feeding on rat liver microsomes (author's transl)].
PubMed:
Effect of hydrogen bonding on electronic spectra and reactivity of flavins.
PubMed:
Rat brain homogenate for in vitro evaluation of anti-lipoperoxide activity of riboflavin tetrabutyrate.
PubMed:
The effect of riboflavin tetrabutyrate on lipoperoxide content of oils and experimental hyperlipaemia on rats and rabbits and its comparison with clofibrate.
PubMed:
Nitrogen-15 and carbon-13 nuclear magnetic resonance of reduced flavins. Comparative study with oxidized flavins.
PubMed:
Urinary and serum flavin levels after a single dose of riboflavin or riboflavin tetrabutyrate in man.
PubMed:
Serum flavin levels and urinary excretion of riboflavin and riboflavin tetrabutyrate--a comparative evaluation.
PubMed:
Studies on the effect of riboflavin tetrabutyrate on the atherosclerosis induced by cholesterol feeding in rabbits. II. Effect of riboflavin tetrabutyrate on the formation of atherosclerosis.
PubMed:
Studies on the effect of riboflavin tetrabutyrate on the atherosclerosis induced by cholesterol feeding in rabbits. I. Effect of riboflavin tetrabutyrate on serum and hepatic lipids.
PubMed:
Crystalline molecular complex of riboflavin tetrabutyrate and N,N-dimethyl-4-aminoazobenzene.
PubMed:
Effect of riboflavin tetrabutyrate on degradation of -lipoprotein by fatty acid peroxide.
PubMed:
Studies on fatty acid esters of flavins. 8. Mechanism of hydrolysis of riboflavin tetrabutyrate by pancreatic lipase.
PubMed:
Studies on fatty acid esters of flavins. VII. Reaction of riboflavin tetrabutyrate with linoleic acid under ultra violet light irradiation.
PubMed:
Direct absorption of riboflavin tetrabutyrate through digestive canal.
PubMed:
Studies on fatty acid esters of flavins. VI. Incorporation of riboflavin part of riboflavin tetrabutyrate-2-14C into flavin nucleotides in the organs of rat.
PubMed:
[Studies on riboflavin tetrabutyrate (B2-But) and its effects on p-dimethylaminoazobenzene (DAB) induced hepatoma or degenerated liver of the rat; ESR spectra of the subfraction of lipoperoxide extracted from the liver and several enzyme activities of the same tissue].
PubMed:
[Studies on heterocyclic compounds. VII. Electronic properties of riboflavin. (1). Electronic spectra of isoalloxazine core. Observation with nonaqueous solutions of riboflavin tetrabutyrate].
PubMed:
Absorption and fluorescence spectra of riboflavin tetrabutyrate in various solvents.