2-methyl thiazolidine

thiazolidine, 2-methyl-

CAS: 24050-16-6 C4 H9 N S MW: 103.18773000 meaty

Identification

Name2-methyl thiazolidine
IUPAC2-methyl-1,3-thiazolidine
CAS Number24050-16-6
FDA UNII938P672IFL
Molecular FormulaC4 H9 N S
Molecular Weight103.18773000
MDL NumberMFCD00053110
Nikkaji NumberJ48.807K
Beilstein0102519

Regulatory

Physical Properties

Appearance colorless clear liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.51900 to 1.52500 @ 25.00 °C.
Pounds per Gallon - (est). 12.640 to 12.690
Refractive Index 1.52200 to 1.52800 @ 20.00 °C.
Boiling Point 160.00 °C. @ 760.00 mm Hg
Vapor Pressure 1.608000 mmHg @ 25.00 °C. (est)
Flash Point 132.00 °F. TCC ( 55.56 °C. )
logP (o/w) -1.189 (est)
Soluble in alcohol
Insoluble in water

Organoleptic Properties

Odor Description at 0.01 % in propylene glycol.

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityintraperitoneal-mouse LD50 250 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavoring agents
Recommendation for 2-methyl thiazolidine usage levels up tonot for fragrance use.
Maximised Survey-derived Daily Intakes (MSDI-EU)0.024 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI)160 (μg/person/day)
Threshold of Concern540 (μg/person/day)
Structure ClassII
Dairy products, excluding products of category 02.0 (01.0)0.40000
Fats and oils, and fat emulsions (type water-in-oil) (02.0)0.20000
Edible ices, including sherbet and sorbet (03.0)0.40000
Processed fruit (04.1)0.30000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2)-
Confectionery (05.0)0.40000
Chewing gum (05.3)-
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0)0.20000
Bakery wares (07.0)0.40000
Meat and meat products, including poultry and game (08.0)0.10000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0)0.10000
Eggs and egg products (10.0)-
Sweeteners, including honey (11.0)-
Salts, spices, soups, sauces, salads, protein products, etc. (12.0)0.20000
Foodstuffs intended for particular nutritional uses (13.0)0.40000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1)0.20000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2)0.40000
Ready-to-eat savouries (15.0)1.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0)0.20000

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Potential Uses

FL bacon FL beef FL beef roasted beef FL broth FL chicken condiments FR hawthorn FL lamb FL liver FL meat FL meat grilled meat FL meat roasted meat FL meat smoked meat FL pork FL salami FL soup FL turkey

Natural Occurrence

butter heated butter PMC

Synonyms

2- methyl-1,3-thiazolidine 2- methylthiazolidine thiazolidine, 2-methyl- PubMed: The cysteine reaction with diacetyl under wine-like conditions: proposed mechanisms for mixed origins of 2-methylthiazole, 2-methyl-3-thiazoline, 2-methylthiazolidine, and 2,4,5-trimethyloxazole. PubMed: Acetaldehyde removal from indoor air through chemical absorption using L-cysteine. PubMed: Formulation and in-vivo evaluation of L-cysteine chewing gums for binding carcinogenic acetaldehyde in the saliva during smoking. PubMed: Synthesis of chiral pyrrolo[1,2-c]thiazoles via intramolecular dipolar cycloaddition of münchnones: an interesting rearrangement to pyrrolo[1,2-c]thiazines. PubMed: Formation of malonaldehyde and acetaldehyde from the oxidation of 2'-deoxyribonucleosides. PubMed: Quantitative analysis of acetaldehyde in whole blood from human and various animals by gas chromatography. PubMed: Prevention of naphthalene-induced cataract and hepatic glutathione loss by the L-cysteine prodrugs, MTCA and PTCA. PubMed: Selective modulation of non-protein sulfhydryl levels in Ehrlich ascites tumor bearing mice. PubMed: 2-Methylthiazolidine and 4-ethylguaiacol, male sex pheromone components of the cockroachNauphoeta cinerea (dictyoptera, blaberidae): A reinvestigation. PubMed: Failure of glutathione and cysteine prodrugs to block the chlorpropamide-induced inhibition of aldehyde dehydrogenase in vivo. PubMed: Etiological research on gastric cancer and its precursor lesions in Shandong, China. PubMed: Seducin, male sex pheromone of the cockroachNauphoeta cinerea: Isolation, identification, and bioassay. PubMed: Effects of three cysteine pro-drugs on bleomycin-induced lung fibrosis in hamsters. PubMed: Influence of cysteine and nitrate on the endogenous formation of N-nitrosamino acids. PubMed: Urinary excretion of N-nitrosamino acids and nitrate by inhabitants in high- and low-risk areas for stomach cancer in northern Japan. PubMed: Effect of cigarette smoking and dietary factors on the amount of N-nitrosothiazolidine 4-carboxylic acid and N-nitroso-2-methyl-thiazolidine 4-carboxylic acid in human urine. PubMed: Roles of cysteine as both precursor of thiazolidine 4-carboxylic acids found in human urine and possible inhibitor of endogenous N-nitrosation. PubMed: Effects of cysteine pro-drugs on acetaminophen-induced hepatotoxicity. PubMed: Increased loss and decreased synthesis of hepatic glutathione after acute ethanol administration. Turnover studies. PubMed: Occurrence in human urine of new sulphur-containing N-nitrosamino acids N-nitrosothiazolidine 4-carboxylic acid and its 2-methyl derivative, and their formation. PubMed: Urinary excretion products after the administration of 14C-acetaldehyde to rats. PubMed: Prodrugs of L-cysteine as liver-protective agents. 2(RS)-Methylthiazolidine-4(R)-carboxylic acid, a latent cysteine.