sanguinaria canadensis root extract
extract of the roots of the blood root, sanguinaria canadensis l., papaveraceae
Identification
| Name | sanguinaria canadensis root extract |
| IUPAC | sanguinaria canadensis l. root extract |
| CAS Number | 84929-48-6 |
| FDA UNII | Search |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic ingredient for skin conditioning |
| Recommendation for sanguinaria canadensis root extract usage levels up to | not for fragrance use. |
| Recommendation for sanguinaria canadensis root extract flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
blood root extract
bloodroot root extract
extract of the roots of the blood root, sanguinaria canadensis l., papaveraceae
red-
puccoon root extract
sanguinaria australis root extract
sanguinaria canadensis var. rotundifolia root extract
sanguinaria dilleniana root extract
sanguinaria root extract
PubMed:
Sanguinarine Induces Apoptosis of Human Oral Squamous Cell Carcinoma KB Cells via Inactivation of the PI3K/Akt Signaling Pathway.
PubMed:
Antitumor effects of the benzophenanthridine alkaloid sanguinarine: Evidence and perspectives.
PubMed:
Apoptotic Effects of Sanguinarine on the Organ of Corti 1 Cells: Comparison with Cisplatin.
PubMed:
Rapid human melanoma cell death induced by sanguinarine through oxidative stress.
PubMed:
Consequences of intratumoral injection of a herbal preparation containing blood root (Sanguinaria canadensis) extract in two dogs.
PubMed:
The mechanism of action of sanguinarine against methicillin-resistant Staphylococcus aureus.
PubMed:
An Internet misadventure: bloodroot salve toxicity.
PubMed:
Bloodroot (Sanguinaria canadensis L., Papaveraceae) Enhances Proliferation and Cytokine Production by Human Peripheral Blood Mononuclear Cells in an In Vitro Model.
PubMed:
Sanguinarine sensitizes human gastric adenocarcinoma AGS cells to TRAIL-mediated apoptosis via down-regulation of AKT and activation of caspase-3.
PubMed:
In vitro screening for the tumoricidal properties of international medicinal herbs.
PubMed:
Sanguinarine-induced apoptosis in human leukemia U937 cells via Bcl-2 downregulation and caspase-3 activation.
PubMed:
Sanguinarine-induced apoptosis: generation of ROS, down-regulation of Bcl-2, c-FLIP, and synergy with TRAIL.
PubMed:
Effects of aqueous extracts from five species of the family Papaveraceae on selected aquatic organisms.
PubMed:
Induction of apoptosis by sanguinarine in C6 rat glioblastoma cells is associated with the modulation of the Bcl-2 family and activation of caspases through downregulation of extracellular signal-regulated kinase and Akt.
PubMed:
Sanguinarine inhibits VEGF-induced angiogenesis in a fibrin gel matrix.
PubMed:
Induction of necrosis and apoptosis to KB cancer cells by sanguinarine is associated with reactive oxygen species production and mitochondrial membrane depolarization.
PubMed:
Antiplatelet effect of sanguinarine is correlated to calcium mobilization, thromboxane and cAMP production.
PubMed:
Suppression of angiogenesis by the plant alkaloid, sanguinarine.
PubMed:
Activation of prodeath Bcl-2 family proteins and mitochondrial apoptosis pathway by sanguinarine in immortalized human HaCaT keratinocytes.