sanguinaria canadensis root extract

extract of the roots of the blood root, sanguinaria canadensis l., papaveraceae

CAS: 84929-48-6

Identification

Namesanguinaria canadensis root extract
IUPACsanguinaria canadensis l. root extract
CAS Number84929-48-6
FDA UNIISearch

Regulatory

Physical Properties

Food Chemicals Codex Listed No

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin conditioning

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic ingredient for skin conditioning
Recommendation for sanguinaria canadensis root extract usage levels up tonot for fragrance use.
Recommendation for sanguinaria canadensis root extract flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

sanguinaria canadensis root

Synonyms

blood root extract bloodroot root extract extract of the roots of the blood root, sanguinaria canadensis l., papaveraceae red- puccoon root extract sanguinaria australis root extract sanguinaria canadensis var. rotundifolia root extract sanguinaria dilleniana root extract sanguinaria root extract PubMed: Sanguinarine Induces Apoptosis of Human Oral Squamous Cell Carcinoma KB Cells via Inactivation of the PI3K/Akt Signaling Pathway. PubMed: Antitumor effects of the benzophenanthridine alkaloid sanguinarine: Evidence and perspectives. PubMed: Apoptotic Effects of Sanguinarine on the Organ of Corti 1 Cells: Comparison with Cisplatin. PubMed: Rapid human melanoma cell death induced by sanguinarine through oxidative stress. PubMed: Consequences of intratumoral injection of a herbal preparation containing blood root (Sanguinaria canadensis) extract in two dogs. PubMed: The mechanism of action of sanguinarine against methicillin-resistant Staphylococcus aureus. PubMed: An Internet misadventure: bloodroot salve toxicity. PubMed: Bloodroot (Sanguinaria canadensis L., Papaveraceae) Enhances Proliferation and Cytokine Production by Human Peripheral Blood Mononuclear Cells in an In Vitro Model. PubMed: Sanguinarine sensitizes human gastric adenocarcinoma AGS cells to TRAIL-mediated apoptosis via down-regulation of AKT and activation of caspase-3. PubMed: In vitro screening for the tumoricidal properties of international medicinal herbs. PubMed: Sanguinarine-induced apoptosis in human leukemia U937 cells via Bcl-2 downregulation and caspase-3 activation. PubMed: Sanguinarine-induced apoptosis: generation of ROS, down-regulation of Bcl-2, c-FLIP, and synergy with TRAIL. PubMed: Effects of aqueous extracts from five species of the family Papaveraceae on selected aquatic organisms. PubMed: Induction of apoptosis by sanguinarine in C6 rat glioblastoma cells is associated with the modulation of the Bcl-2 family and activation of caspases through downregulation of extracellular signal-regulated kinase and Akt. PubMed: Sanguinarine inhibits VEGF-induced angiogenesis in a fibrin gel matrix. PubMed: Induction of necrosis and apoptosis to KB cancer cells by sanguinarine is associated with reactive oxygen species production and mitochondrial membrane depolarization. PubMed: Antiplatelet effect of sanguinarine is correlated to calcium mobilization, thromboxane and cAMP production. PubMed: Suppression of angiogenesis by the plant alkaloid, sanguinarine. PubMed: Activation of prodeath Bcl-2 family proteins and mitochondrial apoptosis pathway by sanguinarine in immortalized human HaCaT keratinocytes.