sargachromanol E
chromene isolated from the alga, sargassum siliquastrum (sargachromanol E)
Identification
| Name | sargachromanol E |
| IUPAC | (4S,5S,6E,10E)-13-[(2R)-6-hydroxy-2,8-dimethyl-3,4-dihydrochromen-2-yl]-2,6,10-trimethyltrideca-2,6,10-triene-4,5-diol |
| CAS Number | 856414-54-5 |
| FDA UNII | JMY24R181A |
| Molecular Formula | C27 H40 O4 |
| Molecular Weight | 428.61260000 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 0.0008333 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic ingredient for skin conditioning |
| Recommendation for sargachromanol E usage levels up to | not for fragrance use. |
| Recommendation for sargachromanol E flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
chromene isolated from the alga, sargassum siliquastrum (sargachromanol E)
(4S,5S,6E,10E)-13-[(2R)-6-
hydroxy-2,8-dimethyl-3,4-dihydro-2H-chromen-2-yl]-2,6,10-trimethyl-2,6,10-tridecatriene-4,5-diol
(4S,5S,6E,10E)-13-[(2R)-6-
hydroxy-2,8-dimethyl-3,4-dihydrochromen-2-yl]-2,6,10-trimethyltrideca-2,6,10-triene-4,5-diol
2,6,10-
tridecatriene-4,5-diol, 13-[(2R)-3,4-dihydro-6-hydroxy-2,8-dimethyl-2H-1-benzopyran-2-yl]-2,6,10-trimethyl-, (4S,5S,6E,10E)-
PubMed:
Preparative isolation of sargachromanol E from Sargassum siliquastrum by centrifugal partition chromatography and its anti-inflammatory activity.
PubMed:
The chromene sargachromanol E inhibits ultraviolet A-induced ageing of skin in human dermal fibroblasts.
PubMed:
Chromene induces apoptosis via caspase-3 activation in human leukemia HL-60 cells.