sialyllactose

N-acetylneuraminoyllactose

CAS: 35890-38-1 C23 H39 N O19 MW: 633.55563000

Identification

Namesialyllactose
CAS Number35890-38-1
FDA UNII3J7TAL60G3
Molecular FormulaC23 H39 N O19
Molecular Weight633.55563000
MDL NumberMFCD00166999
Nikkaji NumberJ603.805K
Beilstein0075357

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 1e+006 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin conditioning

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic ingredient for skin conditioning
Recommendation for sialyllactose usage levels up tonot for fragrance use.
Recommendation for sialyllactose flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

N- acetylneuraminoyllactose D- glucose, O-(N-acetyl-alpha-neuraminosyl)-(2-3)-O-beta-D-galactopyranosyl-(1-4)- 3- sialyllactose PubMed: 3'-Sialyllactose protects against osteoarthritic development by facilitating cartilage homeostasis. PubMed: Human milk oligosaccharide consumption by probiotic and human-associated bifidobacteria and lactobacilli. PubMed: Production of human milk oligosaccharides by enzymatic and whole-cell microbial biotransformations. PubMed: Dietary Human Milk Oligosaccharides but Not Prebiotic Oligosaccharides Increase Circulating Natural Killer Cell and Mesenteric Lymph Node Memory T Cell Populations in Noninfected and Rotavirus-Infected Neonatal Piglets. PubMed: Growth and Morbidity of Gambian Infants are Influenced by Maternal Milk Oligosaccharides and Infant Gut Microbiota. PubMed: Fucosyllactose and L-fucose utilization of infant Bifidobacterium longum and Bifidobacterium kashiwanohense. PubMed: Cell-Free Spent Media Obtained from Bifidobacterium bifidum and Bifidobacterium crudilactis Grown in Media Supplemented with 3'-Sialyllactose Modulate Virulence Gene Expression in Escherichia coli O157:H7 and Salmonella Typhimurium. PubMed: Structures of the Streptococcus sanguinis SrpA Binding Region with Human Sialoglycans Suggest Features of the Physiological Ligand. PubMed: Porcine Milk Oligosaccharides and Sialic Acid Concentrations Vary Throughout Lactation. PubMed: Characterization of porcine milk oligosaccharides during early lactation and their relation to the fecal microbiome. PubMed: It All Starts with a Sandwich: Identification of Sialidases with Trans-Glycosylation Activity. PubMed: Temporal Change of the Content of 10 Oligosaccharides in the Milk of Chinese Urban Mothers. PubMed: NMR analysis on the sialic acid-binding mechanism of an R-type lectin mutant by natural evolution-mimicry. PubMed: Galactooligosaccharide and Sialyllactose Content in Commercial Lactose Powders from Goat and Cow Milk. PubMed: Gut microbiota analysis reveals a marked shift to bifidobacteria by a starter infant formula containing a synbiotic of bovine milk-derived oligosaccharides and Bifidobacterium animalis subsp. lactis CNCM I-3446. PubMed: Oligosaccharides in Urine, Blood, and Feces of Piglets Fed Milk Replacer Containing Galacto-oligosaccharides. PubMed: Short communication: Quantification of carbohydrates in whey permeate products using high-performance anion-exchange chromatography with pulsed amperometric detection. PubMed: Comparative transcriptomics reveals key differences in the response to milk oligosaccharides of infant gut-associated bifidobacteria. PubMed: Chemical characterization of milk oligosaccharides of the eastern quoll (Dasyurus viverrinus). PubMed: Attenuation of food allergy symptoms following treatment with human milk oligosaccharides in a mouse model. PubMed: Comparison of milk oligosaccharides pattern in colostrum of different horse breeds. PubMed: In vitro impact of human milk oligosaccharides on Enterobacteriaceae growth. PubMed: 4-O-Acetyl-sialic acid (Neu4,5Ac2) in acidic milk oligosaccharides of the platypus (Ornithorhynchus anatinus) and its evolutionary significance. PubMed: Growth and safety evaluation of infant formulae containing oligosaccharides derived from bovine milk: a randomized, double-blind, noninferiority trial. PubMed: Functional role and mechanisms of sialyllactose and other sialylated milk oligosaccharides. PubMed: Can an ancestral condition for milk oligosaccharides be determined? Evidence from the Tasmanian echidna (Tachyglossus aculeatus setosus). PubMed: Select human milk oligosaccharides directly modulate peripheral blood mononuclear cells isolated from 10-d-old pigs. PubMed: Exposure of Bifidobacterium longum subsp. infantis to Milk Oligosaccharides Increases Adhesion to Epithelial Cells and Induces a Substantial Transcriptional Response. PubMed: Neutral and acidic milk oligosaccharides of the striped skunk (Mephitidae: Mephitis mephitis). PubMed: In vitro fermentation characteristics of select nondigestible oligosaccharides by infant fecal inocula. PubMed: Methodologies for screening of bacteria-carbohydrate interactions: anti-adhesive milk oligosaccharides as a case study. PubMed: Biotechnological production of human milk oligosaccharides. PubMed: Quantification of bovine milk oligosaccharides using liquid chromatography-selected reaction monitoring-mass spectrometry. PubMed: Chemical characterization of the oligosaccharides in Bactrian camel (Camelus bactrianus) milk and colostrum. PubMed: Neutral and acidic oligosaccharides in Holstein-Friesian colostrum during the first 3 days of lactation measured by high performance liquid chromatography on a microfluidic chip and time-of-flight mass spectrometry. PubMed: Permeate from cheese whey ultrafiltration is a source of milk oligosaccharides. PubMed: Determination of sialyl and neutral oligosaccharide levels in transition and mature milks of Samoan women, using anthranilic derivatization followed by reverse phase high performance liquid chromatography. PubMed: Genetic engineering of Escherichia coli for the economical production of sialylated oligosaccharides. PubMed: Sialyl oligosaccharides of human colostrum: changes in concentration during the first three days of lactation. PubMed: Sialyloligosaccharides in human and bovine milk and in infant formulas: variations with the progression of lactation. PubMed: Inhibition of Helicobacter pylori adhesion to human gastric mucus by a high-molecular-weight constituent of cranberry juice.