thiotaurine
ethanesulfonothioic acid, 2-amino-
Identification
| Name | thiotaurine |
| IUPAC | 2-hydroxysulfonothioylethanamine |
| CAS Number | 2937-54-4 |
| EINECS | 220-918-7 |
| FDA UNII | NQZ2D7AO62 |
| Molecular Formula | C2 H7 N O2 S2 |
| Molecular Weight | 141.21319000 |
| Nikkaji Number | J306.861G |
| XlogP3 | -0.10 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 1e+006 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | antioxidants |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | antioxidants |
| Recommendation for thiotaurine usage levels up to | not for fragrance use. |
| Recommendation for thiotaurine flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
2-
aminoethanethiosulfonic acid
ethanesulfonothioic acid, 2-amino-
2-
hydroxysulfonothioylethanamine
PubMed:
A Proteomic Approach to Study the Effect of Thiotaurine on Human Neutrophil Activation.
PubMed:
Thiotaurine protects mouse cerebellar granule neurons from potassium deprivation-induced apoptosis by inhibiting the activation of caspase-3.
PubMed:
Thiotaurine modulates human neutrophil activation.
PubMed:
Comparative evaluation of taurine and thiotaurine as protectants against diabetes-induced nephropathy in a rat model.
PubMed:
The effects of taurine and thiotaurine on oxidative stress in the aorta and heart of diabetic rats.
PubMed:
Protection by taurine and thiotaurine against biochemical and cellular alterations induced by diabetes in a rat model.
PubMed:
Thiotaurine prevents apoptosis of human neutrophils: a putative role in inflammation.
PubMed:
Comparative evaluation of the effects of taurine and thiotaurine on alterations of the cellular redox status and activities of antioxidant and glutathione-related enzymes by acetaminophen in the rat.
PubMed:
Comparison of brain mitochondrial cytochrome c oxidase activity with cyanide LD(50) yields insight into the efficacy of prophylactics.
PubMed:
Thiotaurine and hypotaurine contents in hydrothermal-vent polychaetes without thiotrophic endosymbionts: correlation With sulfide exposure.
PubMed:
Hypotaurine and sulfhydryl-containing antioxidants reduce H2S toxicity in erythrocytes from a marine invertebrate.
PubMed:
Oxidative effects of cigarette smoke on the human skin.
PubMed:
Possible role of a taurine transporter in the deep-sea mussel Bathymodiolus septemdierum in adaptation to hydrothermal vents.
PubMed:
High contents of hypotaurine and thiotaurine in hydrothermal-vent gastropods without thiotrophic endosymbionts.
PubMed:
Development of an LC-MS-MS method for the quantification of taurine derivatives in marine invertebrates.
PubMed:
Possible roles of sulfur-containing amino acids in a chemoautotrophic bacterium-mollusc symbiosis.
PubMed:
Stimulatory effect of sulphide on thiotaurine synthesis in three hydrothermal-vent species from the East Pacific Rise.
PubMed:
Unusual organic osmolytes in deep-sea animals: adaptations to hydrostatic pressure and other perturbants.
PubMed:
In vitro effects of anionic sulfur compounds on the spectrophotometric properties of native DNA.
PubMed:
High amounts of sulphur-amino acids in three symbiotic mytilid bivalves from deep benthic communities.
PubMed:
Displacement of [(3)H]GABA binding to bovine brain receptors by sulfur-containing analogues.
PubMed:
[Enzymatic systems evolved in the conversion of cystamine to thiotaurine and hypotaurine].
PubMed:
Sulfur exchange between thiotaurine and hypotaurine.
PubMed:
The enzymic conversion of cystamine and thiocysteamine into thiotaurine and hypotaurine.
PubMed:
[Enzymatic conversion of cystamine into thiotaurine].
PubMed:
Inability of thiotaurine to protect mice against ionizing radiation.
PubMed:
Degradation of thiotaurine by ionizing radiations.
PubMed:
Chromatographic evidence on the occurrence of thiotaurine in the urine of rats fed with cystine.
PubMed:
On the synthesis and biochemistry of thiotaurine (amino-2-ethanethiosulfonic acid).
PubMed:
[On the synthesis of thiotaurine].