trichosanthes kirilowii root extract
extract of the roots of the chinese gourd, trichosanthes kirilowii, cucurbitaceae
Identification
| Name | trichosanthes kirilowii root extract |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin protecting agents |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic ingredient for skin protecting |
| Recommendation for trichosanthes kirilowii root extract usage levels up to | not for fragrance use. |
| Recommendation for trichosanthes kirilowii root extract flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
extract of the roots of the chinese gourd, trichosanthes kirilowii, cucurbitaceae
trichosanthes obtusiloba root extract
PubMed:
Ribosome-inactivating Proteins from Root Tubers and Seeds of Trichosan-thes kirilowii and Other Trichosanthes Species.
PubMed:
In vitro Screening and Evaluation of 37 Traditional Chinese Medicines for Their Potential to Activate Peroxisome Proliferator-Activated Receptors-γ.
PubMed:
Trichosanthin-induced autophagy in gastric cancer cell MKN-45 is dependent on reactive oxygen species (ROS) and NF-κB/p53 pathway.
PubMed:
The anti-cancerous activity of recombinant trichosanthin on prostate cancer cell PC3.
PubMed:
Trichosanthin suppresses the proliferation of glioma cells by inhibiting LGR5 expression and the Wnt/β-catenin signaling pathway.
PubMed:
A lower pH value benefits regeneration of Trichosanthes kirilowii by somatic embryogenesis, involving rhizoid tubers (RTBs), a novel structure.
PubMed:
BDP-30, a systemic resistance inducer from Boerhaavia diffusa L., suppresses TMV infection, and displays homology with ribosome-inactivating proteins.
PubMed:
[Effect of yanghe huayan decoction on precancerosis of breast cancer, protein and mRNA expression of ki67: an experimental research].
PubMed:
A novel extraction of trichosanthin from Trichosanthes kirilowii roots using three-phase partitioning and its in vitro anticancer activity.
PubMed:
Isolation and characterization of a rhizobacterial antagonist of root-knot nematodes.
PubMed:
Trichosanthin, a Chinese medicine for the medical treatment of ectopic pregnancy with high levels of β-hCG.
PubMed:
Identification of novel pregnane X receptor activators from traditional Chinese medicines.
PubMed:
Possible mechanisms of trichosanthin-induced apoptosis of tumor cells.
PubMed:
Trichosanthin, an extract of Trichosanthes kirilowii, effectively prevents acute rejection of major histocompatibility complex-mismatched mouse skin allograft.
PubMed:
[Tissue culture and rapid propagation of Trichosanthes kirilowii].
PubMed:
Trichosanthin induced Th2 polarization status.
PubMed:
[Protective effects of trichosanthin in Herpes simplex virus-1 encephalitis in mice].
PubMed:
Recent advances in trichosanthin, a ribosome-inactivating protein with multiple pharmacological properties.
PubMed:
Effect of N- and C-terminal deletions on the RNA N-glycosidase activity and the antigenicity of karasurin-A, a ribosome-inactivating protein from Trichosanthes kirilowii var. japonica.
PubMed:
[Activation of G protein on the membrane of TCS-sensitive cells].
PubMed:
[Genetic transformation of hairy roots in Trichosanthes kirilowii Maxim. by Ti and Ri plasmids].
PubMed:
Cucurbitacins from Trichosanthes kirilowii as the inhibitory components on tyrosinase activity and melanin synthesis of B16/F10 melanoma cells.
PubMed:
Expression of recombinant trichosanthin, a ribosome-inactivating protein, in transgenic tobacco.
PubMed:
The interaction of trichosanthin with supported phospholipid membranes studied by surface plasmon resonance.
PubMed:
Anti-HIV-1 activity of trichobitacin, a novel ribosome-inactivating protein.
PubMed:
Carbohydrate specificity of an agglutinin isolated from the root of Trichosanthes kirilowii.
PubMed:
Effect of karasurin-A on nitric oxide production by murine macrophages and mitogenic response of murine splenocytes in vitro.
PubMed:
Amino acid sequences and ribosome-inactivating activities of karasurin-B and karasurin-C.
PubMed:
A new method for the detection and quantitative measurement of the contents of trichosanthes root component composing Chinese traditional medicines.
PubMed:
A simplified procedure for the purification of trichosanthin (a type 1 ribosome inactivating protein) from Trichosanthes kirilowii root tubers.
PubMed:
Cytotoxic activity of bryonolic acid isolated from transformed hairy roots of Trichosanthes kirilowii var. japonica.
PubMed:
In vitro immunotoxicity and cytotoxicity of trichosanthin against human normal immunocytes and leukemia-lymphoma cells.
PubMed:
Biosynthesis of defense-related proteins in transformed root cultures of Trichosanthes kirilowii Maxim. var japonicum (Kitam.).
PubMed:
Development and application of an enzyme immunoassay for karasurin A, an effective protein component of Trichosanthes kirilowii Max. var. japonicum Kitam.
PubMed:
Minireview: trichosanthin--a protein with multiple pharmacological properties.
PubMed:
The mechanism of action of trichosanthin on eukaryotic ribosomes--RNA N-glycosidase activity of the cytotoxin.
PubMed:
Presence of protein polymorphism in karasurin, an abortifacient and anti-tumor protein, identified with physicochemical properties.
PubMed:
Toxicity and activity of purified trichosanthin.
PubMed:
Trichosanthin-monoclonal antibody conjugate specifically cytotoxic to human hepatoma cells in vitro.
PubMed:
The complete amino acid sequence of an abortifacient protein, karasurin.
PubMed:
Isolation and characterization of a new abortifacient protein, karasurin, from root tubers of Trichosanthes kirilowii Max. var. japonicum Kitam.
PubMed:
Cloning of trichosanthin cDNA and its expression in Escherichia coli.
PubMed:
[Studies on the constituents of "Trichosanthes root". IV. Constituents of roots of Trichosanthes multiloba Miq., Trichosanthes miyagii Hay. and Chinese crude drug "karo-kon"].
PubMed:
[Studies on the constituents of trichosanthes root. I. Constituents of roots of Trichosanthes kirilowii Maxim. var. japonicum Kitam].
PubMed:
Beta-trichosanthin: a new abortifacient protein from the Chinese drug, wangua, Trichosanthes cucumeroides.
PubMed:
Isolation and characterization of an immunosuppressive protein from Trichosanthes kirilowii root tubers.
PubMed:
The immunomodulatory and antitumor activities of trichosanthin-an abortifacient protein isolated from tian-hua-fen (Trichosanthes kirilowii).
PubMed:
Chemical and biological characterization of the galactose binding lectins from Trichosanthes kirilowii root tubers.
PubMed:
Selective killing of choriocarcinoma cells in vitro by trichosanthin, a plant protein purified from root tubers of the Chinese medicinal herb Trichosanthes kirilowii.
PubMed:
Screening of Trichosanthes kirilowii, Momordica charantia and Cucurbita maxima (family Cucurbitaceae) for compounds with antilipolytic activity.
PubMed:
Purification, characterization and sequence determination of a double-headed trypsin inhibitor peptide from Trichosanthes kirilowii (a Chinese medical herb).
PubMed:
Studies on the mechanisms of abortion induction by Trichosanthin.