trichosanthes kirilowii root extract

extract of the roots of the chinese gourd, trichosanthes kirilowii, cucurbitaceae

Identification

Nametrichosanthes kirilowii root extract

Regulatory

Physical Properties

Food Chemicals Codex Listed No

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesskin protecting agents

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorycosmetic ingredient for skin protecting
Recommendation for trichosanthes kirilowii root extract usage levels up tonot for fragrance use.
Recommendation for trichosanthes kirilowii root extract flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

trichosanthes kirilowii root

Synonyms

extract of the roots of the chinese gourd, trichosanthes kirilowii, cucurbitaceae trichosanthes obtusiloba root extract PubMed: Ribosome-inactivating Proteins from Root Tubers and Seeds of Trichosan-thes kirilowii and Other Trichosanthes Species. PubMed: In vitro Screening and Evaluation of 37 Traditional Chinese Medicines for Their Potential to Activate Peroxisome Proliferator-Activated Receptors-γ. PubMed: Trichosanthin-induced autophagy in gastric cancer cell MKN-45 is dependent on reactive oxygen species (ROS) and NF-κB/p53 pathway. PubMed: The anti-cancerous activity of recombinant trichosanthin on prostate cancer cell PC3. PubMed: Trichosanthin suppresses the proliferation of glioma cells by inhibiting LGR5 expression and the Wnt/β-catenin signaling pathway. PubMed: A lower pH value benefits regeneration of Trichosanthes kirilowii by somatic embryogenesis, involving rhizoid tubers (RTBs), a novel structure. PubMed: BDP-30, a systemic resistance inducer from Boerhaavia diffusa L., suppresses TMV infection, and displays homology with ribosome-inactivating proteins. PubMed: [Effect of yanghe huayan decoction on precancerosis of breast cancer, protein and mRNA expression of ki67: an experimental research]. PubMed: A novel extraction of trichosanthin from Trichosanthes kirilowii roots using three-phase partitioning and its in vitro anticancer activity. PubMed: Isolation and characterization of a rhizobacterial antagonist of root-knot nematodes. PubMed: Trichosanthin, a Chinese medicine for the medical treatment of ectopic pregnancy with high levels of β-hCG. PubMed: Identification of novel pregnane X receptor activators from traditional Chinese medicines. PubMed: Possible mechanisms of trichosanthin-induced apoptosis of tumor cells. PubMed: Trichosanthin, an extract of Trichosanthes kirilowii, effectively prevents acute rejection of major histocompatibility complex-mismatched mouse skin allograft. PubMed: [Tissue culture and rapid propagation of Trichosanthes kirilowii]. PubMed: Trichosanthin induced Th2 polarization status. PubMed: [Protective effects of trichosanthin in Herpes simplex virus-1 encephalitis in mice]. PubMed: Recent advances in trichosanthin, a ribosome-inactivating protein with multiple pharmacological properties. PubMed: Effect of N- and C-terminal deletions on the RNA N-glycosidase activity and the antigenicity of karasurin-A, a ribosome-inactivating protein from Trichosanthes kirilowii var. japonica. PubMed: [Activation of G protein on the membrane of TCS-sensitive cells]. PubMed: [Genetic transformation of hairy roots in Trichosanthes kirilowii Maxim. by Ti and Ri plasmids]. PubMed: Cucurbitacins from Trichosanthes kirilowii as the inhibitory components on tyrosinase activity and melanin synthesis of B16/F10 melanoma cells. PubMed: Expression of recombinant trichosanthin, a ribosome-inactivating protein, in transgenic tobacco. PubMed: The interaction of trichosanthin with supported phospholipid membranes studied by surface plasmon resonance. PubMed: Anti-HIV-1 activity of trichobitacin, a novel ribosome-inactivating protein. PubMed: Carbohydrate specificity of an agglutinin isolated from the root of Trichosanthes kirilowii. PubMed: Effect of karasurin-A on nitric oxide production by murine macrophages and mitogenic response of murine splenocytes in vitro. PubMed: Amino acid sequences and ribosome-inactivating activities of karasurin-B and karasurin-C. PubMed: A new method for the detection and quantitative measurement of the contents of trichosanthes root component composing Chinese traditional medicines. PubMed: A simplified procedure for the purification of trichosanthin (a type 1 ribosome inactivating protein) from Trichosanthes kirilowii root tubers. PubMed: Cytotoxic activity of bryonolic acid isolated from transformed hairy roots of Trichosanthes kirilowii var. japonica. PubMed: In vitro immunotoxicity and cytotoxicity of trichosanthin against human normal immunocytes and leukemia-lymphoma cells. PubMed: Biosynthesis of defense-related proteins in transformed root cultures of Trichosanthes kirilowii Maxim. var japonicum (Kitam.). PubMed: Development and application of an enzyme immunoassay for karasurin A, an effective protein component of Trichosanthes kirilowii Max. var. japonicum Kitam. PubMed: Minireview: trichosanthin--a protein with multiple pharmacological properties. PubMed: The mechanism of action of trichosanthin on eukaryotic ribosomes--RNA N-glycosidase activity of the cytotoxin. PubMed: Presence of protein polymorphism in karasurin, an abortifacient and anti-tumor protein, identified with physicochemical properties. PubMed: Toxicity and activity of purified trichosanthin. PubMed: Trichosanthin-monoclonal antibody conjugate specifically cytotoxic to human hepatoma cells in vitro. PubMed: The complete amino acid sequence of an abortifacient protein, karasurin. PubMed: Isolation and characterization of a new abortifacient protein, karasurin, from root tubers of Trichosanthes kirilowii Max. var. japonicum Kitam. PubMed: Cloning of trichosanthin cDNA and its expression in Escherichia coli. PubMed: [Studies on the constituents of "Trichosanthes root". IV. Constituents of roots of Trichosanthes multiloba Miq., Trichosanthes miyagii Hay. and Chinese crude drug "karo-kon"]. PubMed: [Studies on the constituents of trichosanthes root. I. Constituents of roots of Trichosanthes kirilowii Maxim. var. japonicum Kitam]. PubMed: Beta-trichosanthin: a new abortifacient protein from the Chinese drug, wangua, Trichosanthes cucumeroides. PubMed: Isolation and characterization of an immunosuppressive protein from Trichosanthes kirilowii root tubers. PubMed: The immunomodulatory and antitumor activities of trichosanthin-an abortifacient protein isolated from tian-hua-fen (Trichosanthes kirilowii). PubMed: Chemical and biological characterization of the galactose binding lectins from Trichosanthes kirilowii root tubers. PubMed: Selective killing of choriocarcinoma cells in vitro by trichosanthin, a plant protein purified from root tubers of the Chinese medicinal herb Trichosanthes kirilowii. PubMed: Screening of Trichosanthes kirilowii, Momordica charantia and Cucurbita maxima (family Cucurbitaceae) for compounds with antilipolytic activity. PubMed: Purification, characterization and sequence determination of a double-headed trypsin inhibitor peptide from Trichosanthes kirilowii (a Chinese medical herb). PubMed: Studies on the mechanisms of abortion induction by Trichosanthin.