tyrosinase

copper-containing enzyme that catalyzes the hydrolysis of tyrosine PubMed: Whitening and anti-wrinkle activities of ferulic acid isolated from Tetragonia tetragonioides in B16F10 melanoma and CCD-986sk fibroblast cells. PubMed: Inhibition of NAT10 Suppresses Melanogenesis and Melanoma Growth by Attenuating Microphthalmia-Associated Transcription Factor (MITF) Expression. PubMed: Inhibition of tyrosinase by cherimoya pericarp proanthocyanidins: Structural characterization, inhibitory activity and mechanism. PubMed: Oil-in-water emulsions stabilized by tyrosinase-crosslinked potato protein. PubMed: Quercetin as a tyrosinase inhibitor: Inhibitory activity, conformational change and mechanism. PubMed: Anti-Melanogenic Effects of Flavonoid Glycosides from Limonium tetragonum (Thunb.) Bullock via Inhibition of Tyrosinase and Tyrosinase-Related Proteins. PubMed: Electrochemical enzyme biosensors based on calcium phosphate materials for tyramine detection in food samples. PubMed: Protocatechuic Acid from Pear Inhibits Melanogenesis in Melanoma Cells. PubMed: Purification and Characterization of Latent Polyphenol Oxidase from Apricot (Prunus armeniaca L.). PubMed: Biological effects and chemical characterization of Iris schachtii Markgr. extracts: A new source of bioactive constituents. PubMed: Quinoxaline-, dopamine-, and amino acid-derived metabolites from the edible insect Protaetia brevitarsis seulensis. PubMed: The integrated analysis of RNA-seq and microRNA-seq depicts miRNA-mRNA networks involved in Japanese flounder (Paralichthys olivaceus) albinism. PubMed: Spectrum Effect Relationship and Component Knock-Out in Angelica Dahurica Radix by High Performance Liquid Chromatography-Q Exactive Hybrid Quadrupole-Orbitrap Mass Spectrometer. PubMed: Gamma-Irradiated Luteolin Inhibits 3-Isobutyl-1-Methylxanthine-Induced Melanogenesis Through the Regulation of CREB/MITF, PI3K/Akt, and ERK Pathways in B16BL6 Melanoma Cells. PubMed: Antimelanogenic Effect of Urolithin A and Urolithin B, the Colonic Metabolites of Ellagic Acid, in B16 Melanoma Cells. PubMed: White grape pomace extracts, obtained by a sequential enzymatic plus ethanol-based extraction, exert antioxidant, anti-tyrosinase and anti-inflammatory activities. PubMed: An inhibition mechanism of dihydromyricetin on tyrosinase and the joint effects of vitamins B6, D3 or E. PubMed: Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis. PubMed: Kinetics of Tyrosinase Inhibitory Activity Using Vitis vinifera Leaf Extracts. PubMed: Young leaves of reed (Phragmites communis) suppress melanogenesis and oxidative stress in B16F10 melanoma cells. PubMed: Chemical composition and biological studies of the essential oil from aerial parts of beta vulgaris subsp. maritima (L.) arcang. growing in Tunisia. PubMed: Inhibitory effects of Stichopus japonicus extract on melanogenesis of mouse cells via ERK phosphorylation. PubMed: Inhibitory effect of Gastrodia elata Blume extract on alpha-melanocyte stimulating hormone-induced melanogenesis in murine B16F10 melanoma. PubMed: Melanin-gamma rays assistants for bismuth oxide nanoparticles synthesis at room temperature for enhancing antimicrobial, and photocatalytic activity. PubMed: Carvacrol derivatives as mushroom tyrosinase inhibitors; synthesis, kinetics mechanism and molecular docking studies. PubMed: Novel inhibitors of tyrosinase produced by the 4-substitution of TCT (П). PubMed: Inhibition on cholinesterase and tyrosinase by alkaloids and phenolics from Aristotelia chilensis leaves. PubMed: Boosting LPMO-driven lignocellulose degradation by polyphenol oxidase-activated lignin building blocks. PubMed: Tyrosinase inhibitory mechanism of betulinic acid from Dillenia indica. PubMed: Mechanistic insights into tyrosinase-mediated crosslinking of soy glycinin derived peptides. PubMed: Tyrosinase inhibitory activity, molecular docking studies and antioxidant potential of chemotypes of Lippia origanoides (Verbenaceae) essential oils. PubMed: Effects of matsutake mushroom scent compounds on tyrosinase and murine B16-F10 melanoma cells. PubMed: Structuring colloidal oat and faba bean protein particles via enzymatic modification. PubMed: Chemical constituents, radical scavenging activity and enzyme inhibitory capacity of fruits from Cotoneaster pannosus Franch. PubMed: Inhibition of melanogenesis by jineol from Scolopendra subspinipes mutilans via MAP-Kinase mediated MITF downregulation and the proteasomal degradation of tyrosinase. PubMed: Combining in vitro, in vivo and in silico approaches to evaluate nutraceutical potentials and chemical fingerprints of Moltkia aurea and Moltkia coerulea. PubMed: Spectrophotometric Characterization of the Action of Tyrosinase on p-Coumaric and Caffeic Acids: Characteristics of o-Caffeoquinone. PubMed: Identification of conserved proteins from diverse shell matrix proteome in Crassostrea gigas: characterization of genetic bases regulating shell formation. PubMed: Antioxidant capacity of phenolic compounds on human cell lines as affected by grape-tyrosinase and Botrytis-laccase oxidation. PubMed: New caffeic acid derivative from Tithonia diversifolia (Hemsl.) A. Gray butanolic extract and its antioxidant activity. PubMed: Bioactivities of Achillea phrygia and Bupleurum croceum based on the composition of phenolic compounds: In vitro and in silico approaches. PubMed: Antioxidant and Anti-tyrosinase Activities of Phenolic Extracts from Rape Bee Pollen and Inhibitory Melanogenesis by cAMP/MITF/TYR Pathway in B16 Mouse Melanoma Cells. PubMed: Traditionally Used Lathyrus Species: Phytochemical Composition, Antioxidant Activity, Enzyme Inhibitory Properties, Cytotoxic Effects, and in silico Studies of L. czeczottianus and L. nissolia. PubMed: Screening of Peruvian Medicinal Plants for Tyrosinase Inhibitory Properties: Identification of Tyrosinase Inhibitors in Hypericum laricifolium Juss. PubMed: Cosmeceutical Effects of Galactomannan Fraction from Arenga pinnata Fruits In vitro. PubMed: Phenolic profile, antioxidant activity and enzyme inhibitory activities of extracts from aromatic plants used in Mediterranean diet. PubMed: Allergenicity and Oral Tolerance of Enzymatic Cross-Linked Tropomyosin Evaluated Using Cell and Mouse Models. PubMed: Shedding light on the biological and chemical fingerprints of three Achillea species (A. biebersteinii, A. millefolium and A. teretifolia). PubMed: Garcinia subelliptica Merr. (Fukugi): A multipurpose coastal tree with promising medicinal properties. PubMed: Anti-melasma codrug of retinoic acid assists cutaneous absorption with attenuated skin irritation. PubMed: Proanthocyanidins purified from fruit pericarp of Clausena lansium (Lour.) Skeels as efficient tyrosinase inhibitors: structure evaluation, inhibitory activity and molecular mechanism. PubMed: Antimelanogenic, Antioxidant and Antiproliferative Effects of Antrodia camphorata Fruiting Bodies on B16-F0 Melanoma Cells. PubMed: Peptide Fractions Obtained from Rice By-Products by Means of an Environment-Friendly Process Show In Vitro Health-Related Bioactivities. PubMed: Chemical composition and some biological activities of the essential oils from basil Ocimum different cultivars. PubMed: Functional constituents of wild and cultivated Goji (L. barbarum L.) leaves: phytochemical characterization, biological profile, and computational studies. PubMed: Peroxisome proliferator-activated receptor α (PPARα) contributes to control of melanogenesis in B16 F10 melanoma cells. PubMed: Investigating the inhibitory activity and mechanism differences between norartocarpetin and luteolin for tyrosinase: A combinatory kinetic study and computational simulation analysis. PubMed: Alisol B, a triterpene from Alismatis rhizoma (dried rhizome of Alisma orientale), inhibits melanin production in murine B16 melanoma cells. PubMed: Characterization of glabridin/hydroxypropyl-β-cyclodextrin inclusion complex with robust solubility and enhanced bioactivity. PubMed: Novel inhibitors of tyrosinase produced by the 4-substitution of TCT. PubMed: Functional Properties of Novel Epigallocatechin Gallate Glucosides Synthesized by Using Dextransucrase from Leuconostoc mesenteroides B-1299CB4. PubMed: Mechanism and kinetics of tyrosinase inhibition by glycolic acid: a study using conventional spectroscopy methods and hydrogen/deuterium exchange coupling with mass spectrometry. PubMed: The inhibition effect of starch nanoparticles on tyrosinase activity and its mechanism. PubMed: The depigmenting effect of natural resorcinol type polyphenols Kuwanon O and Sanggenon T from the roots of morus australis. PubMed: Thyroid Hormones Regulate Zebrafish Melanogenesis in a Gender-Specific Manner. PubMed: Anti-Melanogenic Activities of Heracleum moellendorffii via ERK1/2-Mediated MITF Downregulation. PubMed: Molecular Cloning and Characteristic Features of a Novel Extracellular Tyrosinase from Aspergillus niger PA2. PubMed: Chemical exploration of 4-(4-fluorobenzyl)piperidine fragment for the development of new tyrosinase inhibitors. PubMed: Rice Bran Protein as a Potent Source of Antimelanogenic Peptides with Tyrosinase Inhibitory Activity. PubMed: Bioactive and functional properties of sour cherry juice (Prunus cerasus). PubMed: Multicomponent pattern and biological activities of seven Asphodeline taxa: potential sources of natural-functional ingredients for bioactive formulations. PubMed: Biological evaluation of two Keggin-type polyoxometalates containing glycine as mushroom tyrosinase inhibitors. PubMed: Tyrosinase inhibitory properties of phenylpropanoid glycosides and flavonoids from Teucrium polium L. var. gnaphalodes. PubMed: The unravelling of the complex pattern of tyrosinase inhibition. PubMed: Peroxidase can perform the hydroxylation step in the 'oxidative cascade' during oxidation of tea catechins. PubMed: Jasmine rice panicle: A safe and efficient natural ingredient for skin aging treatments. PubMed: Seasonal dynamics of the phytochemical constituents and bioactivities of extracts from Stenoloma chusanum (L.) Ching. PubMed: Demethyleugenol β-Glucopyranoside Isolated from Agastache rugosa Decreases Melanin Synthesis via Down-regulation of MITF and SOX9. PubMed: A Novel Heptapeptide with Tyrosinase Inhibitory Activity Identified from a Phage Display Library. PubMed: Activity changes of antioxidant and detoxifying enzymes in Tenebrio molitor (Coleoptera: Tenebrionidae) larvae infected by the entomopathogenic nematode Heterorhabditis beicherriana (Rhabditida: Heterorhabditidae). PubMed: Effect of Cd(2+) on tyrosinase: Integration of inhibition kinetics with computational simulation. PubMed: Extract of Ganoderma formosanum Mycelium as a Highly Potent Tyrosinase Inhibitor. PubMed: Characterization of a New Flavone and Tyrosinase Inhibition Constituents from the Twigs of Morus alba L. PubMed: Large-Scale Recombinant Expression and Purification of Human Tyrosinase Suitable for Structural Studies. PubMed: Effect of inhibition on tyrosinase and melanogenesis of Agastache rugosa Kuntze by lactic acid bacteria fermentation. PubMed: Real-time monitoring of glucose and phenols intestinal absorption through an integrated Caco-2TC7cells/biosensors telemetric device: Hypoglycemic effect of fruit phytochemicals. PubMed: Interaction of small molecules with human tyrosinase: A surface plasmon resonance and molecular docking study. PubMed: Improved antioxidant and anti-tyrosinase activity of polysaccharide from Sargassum fusiforme by degradation. PubMed: Chemical and biological insights on Cotoneaster integerrimus: A new (-)- epicatechin source for food and medicinal applications. PubMed: A tandem mass spectrometry method based on selected ions detects low-abundance phenolics in black tea - theatridimensins as products of the oxidative cascade. PubMed: Biofunctional Activities of Equisetum ramosissimum Extract: Protective Effects against Oxidation, Melanoma, and Melanogenesis. PubMed: Comparative Depigmentation Effects of Resveratrol and Its Two Methyl Analogues in α-Melanocyte Stimulating Hormone-Triggered B16/F10 Murine Melanoma Cells. PubMed: Annotation of Different Dehydrocatechin Oligomers by MS/MS and Their Occurrence in Black Tea. PubMed: Green tea extract as an anti-browning agent for cloudy apple juice. PubMed: Phenolic compounds and biological effects of edible Rumex scutatus and Pseudosempervivum sempervivum: potential sources of natural agents with health benefits. PubMed: Antimelanogenesis Activity of Hydrolyzed Ginseng Extract (GINST) via Inhibition of JNK Mitogen-activated Protein Kinase in B16F10 Cells. PubMed: Non-specific binding sites help to explain mixed inhibition in mushroom tyrosinase activities. PubMed: Reactions of Flavonoids with o-Quinones Interfere with the Spectrophotometric Assay of Tyrosinase Activity. PubMed: Effect of Okinawa Propolis on PAK1 Activity, Caenorhabditis elegans Longevity, Melanogenesis, and Growth of Cancer Cells. PubMed: Response Characteristics of Bisphenols on a Metal-Organic Framework-Based Tyrosinase Nanosensor. PubMed: Effect of drying on the bioactive compounds, antioxidant, antibacterial and antityrosinase activities of pomegranate peel. PubMed: Mesoporous carbon-containing voltammetric biosensor for determination of tyramine in food products. PubMed: Design and synthesis of novel hydroxypyridinone derivatives as potential tyrosinase inhibitors. PubMed: A naphthoquinone/SAM-mediated biosensor for olive oil polyphenol content. PubMed: Glutathione as a skin whitening agent: Facts, myths, evidence and controversies. PubMed: Physiological Activities of Thiacremonone Produced in High Temperature and High Pressure Treated Garlic. PubMed: Inhibitory Kinetics of Azachalcones and their Oximes on Mushroom Tyrosinase: A Facile Solid-state Synthesis. PubMed: Emodin isolated from Polygoni Multiflori Ramulus inhibits melanogenesis through the liver X receptor-mediated pathway. PubMed: Recombinant Tyrosinase from Polyporus arcularius: Overproduction in Escherichia coli, Characterization, and Use in a Study of Aurones as Tyrosinase Effectors. PubMed: Oligoesculin fraction induces anti-tumor effects and promotes immune responses on B16-F10 mice melanoma. PubMed: Assessment of the sensitizing capacity and allergenicity of enzymatic cross-linked arginine kinase, the crab allergen. PubMed: Physiological properties of Scomber japonicus meat hydrolysate prepared by subcritical water hydrolysis. PubMed: Crystal structure of recombinant tyrosinase-binding protein MtaL at 1.35 Å resolution. PubMed: Cinnamomum cassia essential oil and its major constituent cinnamaldehyde induced cell cycle arrest and apoptosis in human oral squamous cell carcinoma HSC-3 cells. PubMed: Biodegradation of phenolic compounds by Basidiomycota and its phenol oxidases: A review. PubMed: Molecular mechanisms of flavonoids in melanin synthesis and the potential for the prevention and treatment of melanoma. PubMed: 4-Hydroxy cinnamic acid as mushroom preservation: Anti-tyrosinase activity kinetics and application. PubMed: Effect of the mixtures of squid ink tyrosinase and tannic acid on properties of sardine surimi gel. PubMed: Dermatologic evaluation of cosmetic formulations containing Chrysanthemum indicum extract. PubMed: Aspergillus niger PA2: a novel strain for extracellular biotransformation of L-tyrosine into L-DOPA. PubMed: The albinism of the feral Asinara white donkeys (Equus asinus) is determined by a missense mutation in a highly conserved position of the tyrosinase (TYR) gene deduced protein. PubMed: Whitening Effect of Watersoluble Royal Jelly from South Korea. PubMed: One-pot green synthesis of 1,3,5-triarylpentane-1,5-dione and triarylmethane derivatives as a new class of tyrosinase inhibitors. PubMed: Surface display of glycosylated Tyrosinase related protein-2 (TRP-2) tumour antigen on Lactococcus lactis. PubMed: Antioxidant, Anti-Tyrosinase and Anti-Inflammatory Activities of Oil Production Residues from Camellia tenuifloria. PubMed: Melanosis in Penaeus monodon: Involvement of the Laccase-like Activity of Hemocyanin. PubMed: Anthocyanin contents in the seed coat of black soya bean and their anti-human tyrosinase activity and antioxidative activity. PubMed: Optimisation and Characterisation of Lipase-Catalysed Synthesis of a Kojic Monooleate Ester in a Solvent-Free System by Response Surface Methodology. PubMed: Effect-directed analysis of fresh and dried elderberry (Sambucus nigra L.) via hyphenated planar chromatography. PubMed: Preparation of tyrosinase inhibitors and antibrowning agents using green technology. PubMed: Inhibitory effects of Na7PMo11CuO40 on mushroom tyrosinase and melanin formation and its antimicrobial activities. PubMed: N-Nicotinoyl dopamine inhibits skin pigmentation by suppressing of melanosome transfer. PubMed: Altering the phenolics profile of a green tea leaves extract using exogenous oxidases. PubMed: Quercetin-3-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside suppresses melanin synthesis by augmenting p38 MAPK and CREB signaling pathways and subsequent cAMP down-regulation in murine melanoma cells. PubMed: Extraction conditions of white rose petals for the inhibition of enzymes related to skin aging. PubMed: Antimicrobial, antioxidant and anti-tyrosinase properties of extracts of the Mediterranean parasitic plant Cytinus hypocistis. PubMed: Tyrosinase-based biosensor for determination of bisphenol A in a flow-batch system. PubMed: In vitro efficacy of Bryophyllum pinnatum leaf extracts as potent therapeutics. PubMed: Proton pump inhibitors decrease melanogenesis in melanocytes. PubMed: Influence of Laccase and Tyrosinase on the Antioxidant Capacity of Selected Phenolic Compounds on Human Cell Lines. PubMed: Identification of tyrosinase specific inhibitors from Xanthium strumarium fruit extract using ultrafiltration-high performance liquid chromatography. PubMed: Comparative studies on the chemical and enzymatic stability of alpha- and beta-arbutin. PubMed: Dioscin Derived from Solanum melongena L. "Usukawamarunasu" Attenuates α-MSH-Induced Melanogenesis in B16 Murine Melanoma Cells via Downregulation of Phospho-CREB and MITF. PubMed: Depigmenting Effect of Winter Medicinal Mushroom Flammulna velutipes (Higher Basidiomycetes) on Melanoma Cells. PubMed: Seasonal Variations of Metabolome and Tyrosinase Inhibitory Activity of Lespedeza maximowiczii during Growth Periods. PubMed: Evaluation of the Antioxidant Activities and Tyrosinase Inhibitory Property from Mycelium Culture Extracts. PubMed: Design, synthesis and biological evaluation of hydroxy substituted amino chalcone compounds for antityrosinase activity in B16 cells. PubMed: Structure-Activity Relationship Study of Hydroxycoumarins and Mushroom Tyrosinase. PubMed: Avocado Proanthocyanidins as a Source of Tyrosinase Inhibitors: Structure Characterization, Inhibitory Activity, and Mechanism. PubMed: Inhibitory effect of brazilein on tyrosinase and melanin synthesis: Kinetics and in silico approach. PubMed: Functionalities of conjugated compounds of γ-aminobutyric acid with salicylaldehyde or cinnamaldehyde. PubMed: Inhibitory effect of synthetic aromatic heterocycle thiosemicarbazone derivatives on mushroom tyrosinase: Insights from fluorescence, (1)H NMR titration and molecular docking studies. PubMed: Cornus officinalis Methanol Extract Upregulates Melanogenesis in Melan-a Cells. PubMed: Inhibitory effect of apocarotenoids on the activity of tyrosinase: Multi-spectroscopic and docking studies. PubMed: Evaluation of antioxidant, enzyme inhibition, and cytotoxic activity of three anthraquinones (alizarin, purpurin, and quinizarin). PubMed: Dietary flavonoid aglycones and their glycosides: Which show better biological significance? PubMed: Tyrosinase-Catalyzed Hydroxylation of 4-Hexylresorcinol, an Antibrowning and Depigmenting Agent: A Kinetic Study. PubMed: Two Ganoderma species: profiling of phenolic compounds by HPLC-DAD, antioxidant, antimicrobial and inhibitory activities on key enzymes linked to diabetes mellitus, Alzheimer's disease and skin disorders. PubMed: Development of tyrosinase biosensor based on quantum dots/chitosan nanocomposite for detection of phenolic compounds. PubMed: Antioxidant properties of fermented mango leaf extracts. PubMed: N-Nicotinoyl tyramine, a novel niacinamide derivative, inhibits melanogenesis by suppressing MITF gene expression. PubMed: Melanogenesis inhibitory activity of Korean Undaria pinnatifida in mouse B16 melanoma cells. PubMed: Structure-function correlations in tyrosinases. PubMed: Plant betalains: Chemistry and biochemistry. PubMed: Discovery of Potent Cysteine-Containing Dipeptide Inhibitors against Tyrosinase: A Comprehensive Investigation of 20 × 20 Dipeptides in Inhibiting Dopachrome Formation. PubMed: Inhibitory effects of α-Na8SiW11CoO40 on tyrosinase and its application in controlling browning of fresh-cut apples. PubMed: Sesamol decreases melanin biosynthesis in melanocyte cells and zebrafish: Possible involvement of MITF via the intracellular cAMP and p38/JNK signalling pathways. PubMed: Phenolic Compounds from the Leaves of Stewartia pseudocamellia Maxim. and their Whitening Activities. PubMed: Cellular Anti-Melanogenic Effects of a Euryale ferox Seed Extract Ethyl Acetate Fraction via the Lysosomal Degradation Machinery. PubMed: The pro-enzyme C-terminal processing domain of Pholiota nameko tyrosinase is responsible for folding of the N-terminal catalytic domain. PubMed: Melanogenesis-inducing effect of cirsimaritin through increases in microphthalmia-associated transcription factor and tyrosinase expression. PubMed: α-Glucosidase and tyrosinase inhibitory effects of an abietane type diterpenoid taxoquinone from Metasequoia glyptostroboides. PubMed: Chemical composition and biological activities of essential oil of Beilschmiedia pulverulenta. PubMed: Betalain induction by l-DOPA application confers photoprotection to saline-exposed leaves of Disphyma australe. PubMed: Biofunctional properties of enzymatic squid meat hydrolysate. PubMed: Polyphenoloxidase from Riesling and Dornfelder wine grapes (Vitis vinifera) is a tyrosinase. PubMed: Effect of Light Wavelengths and Coherence on Growth, Enzymes Activity, and Melanin Accumulation of Liquid-Cultured Inonotus obliquus (Ach.:Pers.) Pilát. PubMed: Hesperetin induces melanin production in adult human epidermal melanocytes. PubMed: Cloning and identification of a novel tyrosinase and its overexpression in Streptomyces kathirae SC-1 for enhancing melanin production. PubMed: Effect of the tyrosinase inhibitor (S)-N-trans-feruloyloctopamine from garlic skin on tyrosinase gene expression and melanine accumulation in melanoma cells. PubMed: Discrimination between alternative substrates and inhibitors of tyrosinase. PubMed: Activities of different types of Thai honey on pathogenic bacteria causing skin diseases, tyrosinase enzyme and generating free radicals. PubMed: Preparation, characterization, and preliminary antibrowning evaluations of norartocarpetin microemulsions. PubMed: Hair dyes resorcinol and lawsone reduce production of melanin in melanoma cells by tyrosinase activity inhibition and decreasing tyrosinase and microphthalmia-associated transcription factor (MITF) expression. PubMed: Antioxidant and ACE Inhibitory Activity of Cultivated and Wild Angelica gigas Nakai Extracts Prepared Using Different Extraction Conditions. PubMed: Functionality study of Na6PMo11FeO40 as a mushroom tyrosinase inhibitor. PubMed: Preparation of squid skin collagen hydrolysate as an antihyaluronidase, antityrosinase, and antioxidant agent. PubMed: A simple and sensitive fluorescent sensor for methyl parathion based on L-tyrosine methyl ester functionalized carbon dots. PubMed: Ultrasonic-assisted enzymatic extraction of silymarin from the Silybum marianum seed shell and evaluation of its antioxidant activity in vitro. PubMed: Alpha-substituted derivatives of cinnamaldehyde as tyrosinase inhibitors: inhibitory mechanism and molecular analysis. PubMed: Functional graphene-gold nano-composite fabricated electrochemical biosensor for direct and rapid detection of bisphenol A. PubMed: 3D metal-organic framework as highly efficient biosensing platform for ultrasensitive and rapid detection of bisphenol A. PubMed: Inhibition effects of benzylideneacetone, benzylacetone, and 4-phenyl-2-butanol on the activity of mushroom tyrosinase. PubMed: Survey of phytochemical composition and biological effects of three extracts from a wild plant (Cotoneaster nummularia Fisch. et Mey.): a potential source for functional food ingredients and drug formulations. PubMed: Screening of inhibitors for mushroom tyrosinase using surface plasmon resonance. PubMed: Differentiation-inducing and anti-proliferative activities of lupeol on canine melanoma cells. PubMed: New tyrosinase inhibitors from Paecilomyces gunnii. PubMed: Ginsenoside F1 attenuates hyperpigmentation in B16F10 melanoma cells by inducing dendrite retraction and activating Rho signalling. PubMed: Whitening Effect of Octaphlorethol A Isolated from Ishige foliacea in an In Vivo Zebrafish Model. PubMed: A tyrosinase inhibitor from Aspergillus niger. PubMed: Vitis amurensis Ruprecht root inhibited α-melanocyte stimulating hormone-induced melanogenesis in B16F10 cells. PubMed: Performance of an active paper based on cinnamon essential oil in mushrooms quality. PubMed: Microbial ketonization of ginsenosides F1 and C-K by Lactobacillus brevis. PubMed: Fermented broth in tyrosinase- and melanogenesis inhibition. PubMed: Anti-tyrosinase, antioxidant, and antibacterial activities of novel 5-hydroxy-4-acetyl-2,3-dihydronaphtho[1,2-b]furans. PubMed: Technical note: Advantages and limitations of authenticating Palmera goat dairy products by pyrosequencing the melanocortin 1 receptor (MC1R) gene. PubMed: A potent antibrowning agent from pine needles of Cedrus deodara: 2R,3R-dihydromyricetin. PubMed: Formulation and characterisation of wheat bran oil-in-water nanoemulsions. PubMed: Synthesis and biological evaluation of glucosyl curcuminoids. PubMed: Characterization and storage stability of the extract of Thai mango (Mangifera indica Linn. Cultivar Chok-Anan) seed kernels. PubMed: Determination of tyrosinase substrate-binding modes reveals mechanistic differences between type-3 copper proteins. PubMed: Comparison of in vitro and in vivo phototoxicity tests with S-(-)-10,11-dihydroxyfarnesic acid methyl ester produced by Beauveria bassiana KACC46831. PubMed: Chemical profile and antiacetylcholinesterase, antityrosinase, antioxidant and α-glucosidase inhibitory activity of Cynometra cauliflora L. leaves. PubMed: S-(-)-10,11-dihydroxyfarnesoic acid methyl ester inhibits melanin synthesis in murine melanocyte cells. PubMed: Optimization of Phenolics Extracted from Idesia polycarpa Defatted Fruit Residue and Its Antioxidant and Depigmenting Activity In Vitro and In Vivo. PubMed: Compositional studies and biological activities of some mash bean (Vigna mungo (L.) Hepper) cultivars commonly consumed in Pakistan. PubMed: Inhibitory effects of ginseng seed on melanin biosynthesis. PubMed: Bioactive profiles, antioxidant activities, nitrite scavenging capacities and protective effects on H2O2-injured PC12 cells of Glycyrrhiza glabra L. leaf and root extracts. PubMed: Structure characterization and anti-tyrosinase mechanism of polymeric proanthocyanidins fractionated from kiwifruit pericarp. PubMed: Inhibitory effect of morin on tyrosinase: insights from spectroscopic and molecular docking studies. PubMed: High-level production of melanin by a novel isolate of Streptomyces kathirae. PubMed: Biological activity and molecular docking studies of curcumin-related α,β-unsaturated carbonyl-based synthetic compounds as anticancer agents and mushroom tyrosinase inhibitors. PubMed: Microbial tyrosinases: promising enzymes for pharmaceutical, food bioprocessing, and environmental industry. PubMed: Characterization of antiproliferative activity constituents from Artocarpus heterophyllus. PubMed: A rational workflow for sequential virtual screening of chemical libraries on searching for new tyrosinase inhibitors. PubMed: Investigation of binding-site homology between mushroom and bacterial tyrosinases by using aurones as effectors. PubMed: A premature stop codon in the TYRP1 gene is associated with brown coat colour in the European rabbit (Oryctolagus cuniculus). PubMed: Effect of atmospheric pressure dielectric barrier discharge plasma on the biological activity of naringin. PubMed: Effect of Vetiveria zizanioides essential oil on melanogenesis in melanoma cells: downregulation of tyrosinase expression and suppression of oxidative stress. PubMed: The melanogenesis alteration effects of Achillea millefolium L. essential oil and linalyl acetate: involvement of oxidative stress and the JNK and ERK signaling pathways in melanoma cells. PubMed: In vitro biological evaluation of 100 selected methanol extracts from the traditional medicinal plants of Asia. PubMed: The crystal structure of a crustacean prophenoloxidase provides a clue to understanding the functionality of the type 3 copper proteins. PubMed: Evaluation of the antioxidant and melanogenesis inhibitory properties of pracparatum mungo (lu-do huang). PubMed: An aqueous extract of Limoniastrum guyonianum gall induces anti-tumor effects in melanoma-injected mice via modulation of the immune response. PubMed: Sensitive bi-enzymatic biosensor based on polyphenoloxidases-gold nanoparticles-chitosan hybrid film-graphene doped carbon paste electrode for carbamates detection. PubMed: Betulinic acid isolated from Vitis amurensis root inhibits 3-isobutyl-1-methylxanthine induced melanogenesis via the regulation of MEK/ERK and PI3K/Akt pathways in B16F10 cells. PubMed: Advances in structure-function relationships of tyrosinase from Agaricus bisporus - investigation on heat-induced conformational changes. PubMed: Hepatoprotective effects and antioxidant, antityrosinase activities of phloretin and phloretin isonicotinyl hydrazone. PubMed: Inhibitory effect of corn silk on skin pigmentation. PubMed: Bioelectronic tongue based on lipidic nanostructured layers containing phenol oxidases and lutetium bisphthalocyanine for the analysis of grapes. PubMed: Structure characterization of proanthocyanidins from Caryota ochlandra Hance and their bioactivities. PubMed: Physiological effects of formulation containing tannase-converted green tea extract on skin care: physical stability, collagenase, elastase, and tyrosinase activities. PubMed: Effects of Danshensu and Salvianolic Acid B from Salvia miltiorrhiza Bunge (Lamiaceae) on cell proliferation and collagen and melanin production. PubMed: Using transcription of six Puccinia triticina races to identify the effective secretome during infection of wheat. PubMed: Evaluation of crocin and curcumin affinity on mushroom tyrosinase using surface plasmon resonance. PubMed: pH-induced structural changes of tyrosinase from Agaricus bisporus using fluorescence and in silico methods. PubMed: Stabilization of food dispersions by enzymes. PubMed: Hydroalcoholic extract of Rhodiola rosea L. (Crassulaceae) and its hydrolysate inhibit melanogenesis in B16F0 cells by regulating the CREB/MITF/tyrosinase pathway. PubMed: Isophilippinolide A arrests cell cycle progression and induces apoptosis for anticancer inhibitory agents in human melanoma cells. PubMed: Mushroom tyrosinase inhibition activity of Aloe vera L. gel from different germplasms. PubMed: Potato and mushroom polyphenol oxidase activities are differently modulated by natural plant extracts. PubMed: Antioxidant and tyrosinase inhibitory activities of flavonoids from Trifolium nigrescens Subsp. petrisavi. PubMed: Antioxidant, antityrosinase, anticholinesterase, and nitric oxide inhibition activities of three malaysian macaranga species. PubMed: Structural analysis of proanthocyanidins isolated from fruit stone of Chinese hawthorn with potent antityrosinase and antioxidant activity. PubMed: Tyrosinase inhibitory effect and antioxidative activities of fermented and ethanol extracts of Rhodiola rosea and Lonicera japonica. PubMed: Chemical composition and tyrosinase inhibitory activity of Cinnamomum cassia essential oil. PubMed: Purification of a fucoidan from kelp polysaccharide and its inhibitory kinetics for tyrosinase. PubMed: Applications of Lactobacillus rhamnosus spent culture supernatant in cosmetic antioxidation, whitening and moisture retention applications. PubMed: Hesperidin Suppresses Melanosome Transport by Blocking the Interaction of Rab27A-Melanophilin. PubMed: A chiral ligand exchange CE system for monitoring inhibitory effect of kojic acid on tyrosinase. PubMed: Synthesis, characterization and biological evaluation of paeonol thiosemicarbazone analogues as mushroom tyrosinase inhibitors. PubMed: Sensitizing potential of enzymatically cross-linked peanut proteins in a mouse model of peanut allergy. PubMed: The antibrowning agent sulfite inactivates Agaricus bisporus tyrosinase through covalent modification of the copper-B site. PubMed: Poly-γ-glutamate from Bacillus subtilis inhibits tyrosinase activity and melanogenesis. PubMed: The mechanism of copper uptake by tyrosinase from Bacillus megaterium. PubMed: Cinnamomum cassia essential oil inhibits α-MSH-induced melanin production and oxidative stress in murine B16 melanoma cells. PubMed: Antimelanoma and antityrosinase from Alpinia galangal constituents. PubMed: Tocotrienols enhance melanosome degradation through endosome docking/fusion proteins in B16F10 melanoma cells. PubMed: Tyrosinase inhibitory effects and antioxidative activities of saponins from Xanthoceras Sorbifolia nutshell. PubMed: Inhibitory kinetics of chlorocinnamic acids on mushroom tyrosinase. PubMed: Inhibitory effects of Cyrtomium fortunei J. Smith root extract on melanogenesis. PubMed: Antioxidant, antibrowning, and cytoprotective activities of Ligustrum robustum (Rxob.) Blume extract. PubMed: Physicochemical and biofunctional properties of crab chitosan nanoparticles. PubMed: Analysis of tyrosinase binders from Glycyrrhiza uralensis root: evaluation and comparison of tyrosinase immobilized magnetic fishing-HPLC and reverse ultrafiltration-HPLC. PubMed: Octaphlorethol A isolated from Ishige foliacea inhibits α-MSH-stimulated induced melanogenesis via ERK pathway in B16F10 melanoma cells. PubMed: Immobilized capillary tyrosinase microreactor for inhibitor screening in natural extracts by capillary electrophoresis. PubMed: Design and synthesis of hydroxypyridinone-L-phenylalanine conjugates as potential tyrosinase inhibitors. PubMed: Dihydroasparagusic acid: antioxidant and tyrosinase inhibitory activities and improved synthesis. PubMed: Enzyme inhibitory and antioxidant activities of Viburnum tinus L. relevant to its neuroprotective potential. PubMed: Hordenine, a single compound produced during barley germination, inhibits melanogenesis in human melanocytes. PubMed: Phytochemical contents and enzyme inhibitory and antioxidant properties of Anethum graveolens L. (dill) samples cultivated under organic and conventional agricultural conditions. PubMed: Novel chemical synthesis of ginkgolic acid (13:0) and evaluation of its tyrosinase inhibitory activity. PubMed: Protective effect of topical application of α-tocopherol and/or N-acetyl cysteine on argemone oil/alkaloid-induced skin tumorigenesis in mice. PubMed: Bioactive polyphenols from muscadine grape and blackcurrant stably concentrated onto protein-rich matrices for topical applications. PubMed: Tyrosinase inhibitors from Calceolaria integrifolia s.l.: Calceolaria talcana aerial parts. PubMed: Inhibitory effects of Korean indigenous plants on tyrosinase and melanogenesis. PubMed: Inhibitory mechanism of red globe amaranth on tyrosinase. PubMed: Inhibitory effects of water extract of Flos Inulae on mutation and tyrosinase. PubMed: Effective inhibition of skin cancer, tyrosinase, and antioxidative properties by astaxanthin and astaxanthin esters from the green alga Haematococcus pluvialis. PubMed: Agaricus bisporus and related Agaricus species on lignocellulose: production of manganese peroxidase and multicopper oxidases. PubMed: Total polyphenols and bioactivity of seeds and sprouts in several legumes. PubMed: Thermal inactivation kinetics of Rabdosia serra (Maxim.) Hara leaf peroxidase and polyphenol oxidase and comparative evaluation of drying methods on leaf phenolic profile and bioactivities. PubMed: Molecular inhibitory mechanism of tricin on tyrosinase. PubMed: Inhibitory effects of propyl gallate on tyrosinase and its application in controlling pericarp browning of harvested longan fruits. PubMed: Decolorization and biodegradation of reactive sulfonated azo dyes by a newly isolated Brevibacterium sp. strain VN-15. PubMed: Biofunctional constituents from Liriodendron tulipifera with antioxidants and anti-melanogenic properties. PubMed: Mechanism of silver nanoparticles action on insect pigmentation reveals intervention of copper homeostasis. PubMed: Influencing the monophenolase/diphenolase activity ratio in tyrosinase. PubMed: Biofabricated film with enzymatic and redox-capacitor functionalities to harvest and store electrons. PubMed: Separation of the antioxidant compound quercitrin from Lindera obtusiloba Blume and its antimelanogenic effect on B16F10 melanoma cells. PubMed: Inhibitory effects of geranic acid derivatives on melanin biosynthesis. PubMed: Characterization of tyrosinase inhibitors in the twigs of Cudrania tricuspidata and their structure-activity relationship study. PubMed: Protein cluster formation during enzymatic cross-linking of globular proteins. PubMed: Influence of ultrasound to the activity of tyrosinase. PubMed: Effective cooperation of monoclonal antibody and peptide vaccine for the treatment of mouse melanoma. PubMed: Crude ethanol extracts from grape seeds and peels exhibit anti-tyrosinase activity. PubMed: Fermenting red ginseng enhances its safety and efficacy as a novel skin care anti-aging ingredient: in vitro and animal study. PubMed: Identification of a novel phenolic compound in litchi (Litchi chinensis Sonn.) pericarp and bioactivity evaluation. PubMed: Dioscin: a synergistic tyrosinase inhibitor from the roots of Smilax china. PubMed: Synthesis and structure-activity relationships and effects of phenylpropanoid amides of octopamine and dopamine on tyrosinase inhibition and antioxidation. PubMed: Tyrosinase inhibitory effects and antioxidative activities of novel cinnamoyl amides with amino acid ester moiety. PubMed: Artemisinic acid inhibits melanogenesis through downregulation of C/EBP α-dependent expression of HMG-CoA reductase gene. PubMed: Kinetic study on the tyrosinase and melanin formation inhibitory activities of carthamus yellow isolated from Carthamus tinctorius L. PubMed: The evaluation of depigmenting efficacy in the skin for the development of new whitening agents in Korea. PubMed: Dual inhibition of γ-oryzanol on cellular melanogenesis: inhibition of tyrosinase activity and reduction of melanogenic gene expression by a protein kinase A-dependent mechanism. PubMed: Synthesis of 4'-thiosemicarbazonegriseofulvin and its effects on the control of enzymatic browning and postharvest disease of fruits. PubMed: Influence of polysaccharides and storage during processing on the properties of mango seed kernel extract (microencapsulation). PubMed: Antioxidant and Antityrosinase Activity of Flemingia macrophylla and Glycine tomentella Roots. PubMed: Biological evaluation of coumarin derivatives as mushroom tyrosinase inhibitors. PubMed: Tyrosinase inhibitory components of immature calamondin peel. PubMed: The functional property of egg yolk phosvitin as a melanogenesis inhibitor. PubMed: Anti-inflammatory activities of an ethanol extract of Ecklonia stolonifera in lipopolysaccharide-stimulated RAW 264.7 murine macrophage cells. PubMed: Enhancement of the tyrosinase inhibitory activity of Mori Cortex Radicis extract by biotransformation using Leuconostoc paramesenteroides PR. PubMed: Inhibitory effects of water extract from longan twigs on mutation and nitric oxide production. PubMed: Inhibition effects of mangosenone F from Garcinia mangostana on melanin formation in B16F10 cells. PubMed: Tyrosinase inhibition constituents from the roots of Morus australis. PubMed: Cell-type dependent response of melanoma cells to aloe emodin. PubMed: Action of tyrosinase on ortho-substituted phenols: possible influence on browning and melanogenesis. PubMed: Inhibitory effects of naphthols on the activity of mushroom tyrosinase. PubMed: Changes in tyrosinase specificity by ionic liquids and sodium dodecyl sulfate. PubMed: Nicotinic acid hydroxamate downregulated the melanin synthesis and tyrosinase activity through activating the MEK/ERK and AKT/GSK3β signaling pathways. PubMed: NMR, HPLC-ESI-MS, and MALDI-TOF MS analysis of condensed tannins from Delonix regia (Bojer ex Hook.) Raf. and their bioactivities. PubMed: Inhibition of enzymatic browning of chlorogenic acid by sulfur-containing compounds. PubMed: Betalain production is possible in anthocyanin-producing plant species given the presence of DOPA-dioxygenase and L-DOPA. PubMed: Expression of recombinant mature human tyrosinase from Escherichia coli and exhibition of its activity without phosphorylation or glycosylation. PubMed: An ultrafiltration high-performance liquid chromatography coupled with diode array detector and mass spectrometry approach for screening and characterising tyrosinase inhibitors from mulberry leaves. PubMed: Methyl cinnamate inhibits adipocyte differentiation via activation of the CaMKK2-AMPK pathway in 3T3-L1 preadipocytes. PubMed: Bioactive compounds, antioxidant, xanthine oxidase inhibitory, tyrosinase inhibitory and anti-inflammatory activities of selected agro-industrial by-products. PubMed: Melanogenesis of murine melanoma cells induced by hesperetin, a Citrus hydrolysate-derived flavonoid. PubMed: Synthesis and antityrosinase mechanism of benzaldehyde thiosemicarbazones: novel tyrosinase inhibitors. PubMed: New phenolic compounds hydrothermally extracted from the olive oil byproduct alperujo and their antioxidative activities. PubMed: Momilactione B inhibits protein kinase A signaling and reduces tyrosinase-related proteins 1 and 2 expression in melanocytes. PubMed: Plant-based Paste Fermented by Lactic Acid Bacteria and Yeast: Functional Analysis and Possibility of Application to Functional Foods. PubMed: An optical test strip for the detection of benzoic acid in food. PubMed: Comparative evaluation of rosmarinic acid, methyl rosmarinate and pedalitin isolated from Rabdosia serra (MAXIM.) HARA as inhibitors of tyrosinase and α-glucosidase. PubMed: Isolation and bioactivities of a non-sericin component from cocoon shell silk sericin of the silkworm Bombyx mori. PubMed: Enzymatic routes for the production of mono- and di-glucosylated derivatives of hydroxytyrosol. PubMed: Anti-melanoma, tyrosinase inhibitory and anti-microbial activities of gold nanoparticles synthesized from aqueous leaf extracts of Teraxacum officinale. PubMed: Solid-phase synthesis of mimosine tetrapeptides and their inhibitory activities on neuraminidase and tyrosinase. PubMed: Mushroom tyrosinase inhibitors from mung bean (Vigna radiatae L.) extracts. PubMed: Inhibitory potential of the leaves and berries of Myrtus communis L. (myrtle) against enzymes linked to neurodegenerative diseases and their antioxidant actions. PubMed: Standardised herbal extract of chlorogenic acid from leaves of Etlingera elatior (Zingiberaceae). PubMed: Antimelanogenic effect of c-phycocyanin through modulation of tyrosinase expression by upregulation of ERK and downregulation of p38 MAPK signaling pathways. PubMed: Kojic acid-amino acid amide metal complexes and their melanogenesis inhibitory activities. PubMed: Inhibitory effect of mulberroside A and its derivatives on melanogenesis induced by ultraviolet B irradiation. PubMed: Comparative assessment of tea quality by various analytical and sensory methods with emphasis on tea polyphenols. PubMed: Effects of thymol on mushroom tyrosinase-catalyzed melanin formation. PubMed: Phenolic tyrosinase inhibitors from the stems of Cudrania cochinchinensis. PubMed: Antioxidant, anti-inflammatory and anti-browning activities of hot water extracts of oriental herbal teas. PubMed: Antioxidant and tyrosinase inhibitory constituents from a desugared sugar cane extract, a byproduct of sugar production. PubMed: Effects of tyrosinase and laccase on oat proteins and quality parameters of gluten-free oat breads. PubMed: In-vitro neuroprotective properties of the Maydis stigma extracts from four corn varieties. PubMed: Antioxidant and antimelanogenic behaviors of Paeonia suffruticosa. PubMed: Rapid screening of enzyme inhibitors using profiling of enzyme-metabolite assay by HPLC (PREMA-HPLC). PubMed: Crystal structure of Agaricus bisporus mushroom tyrosinase: identity of the tetramer subunits and interaction with tropolone. PubMed: Synthesis and antityrosinase activities of alkyl 3,4-dihydroxybenzoates. PubMed: Isolation and tyrosinase inhibitory effects of polyphenols from the leaves of persimmon, Diospyros kaki. PubMed: Antibrowning and antimicrobial activities of the water-soluble extract from pine needles of Cedrus deodara. PubMed: Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition. PubMed: Tyrosinase inhibition by water and ethanol extracts of a far eastern sea cucumber, Stichopus japonicus. PubMed: Tetrahydrofolic Acid is a potent suicide substrate of mushroom tyrosinase. PubMed: Melanin synthesis inhibitors from Balanophora fungosa. PubMed: Benzyl benzoates: New phlorizin analogs as mushroom tyrosinase inhibitors. PubMed: Protein analysis by 31p NMR spectroscopy in ionic liquid: quantitative determination of enzymatically created cross-links. PubMed: C-terminal processing of tyrosinase is responsible for activation of Pholiota microspora proenzyme. PubMed: Aggregation and homogenization, surface charge and structural change, and inactivation of mushroom tyrosinase in an aqueous system by subcritical/supercritical carbon dioxide. PubMed: Interaction of sesamol (3,4-methylenedioxyphenol) with tyrosinase and its effect on melanin synthesis. PubMed: Antioxidant and antityrosinase activity of mulberry (Morus alba L.) twigs and root bark. PubMed: Irreversible competitive inhibitory kinetics of cardol triene on mushroom tyrosinase. PubMed: Effect of protein structural integrity on cross-linking by tyrosinase evidenced by multidimensional heteronuclear magnetic resonance spectroscopy. PubMed: Inhibition kinetics of chlorobenzaldehyde thiosemicarbazones on mushroom tyrosinase. PubMed: First structures of an active bacterial tyrosinase reveal copper plasticity. PubMed: Crystallization and preliminary X-ray crystallographic analysis of a bacterial tyrosinase from Bacillus megaterium. PubMed: Isolation and identification of radical scavenging and tyrosinase inhibition of polyphenols from Tibouchina semidecandra L. PubMed: Synthesis and structure-activity relationship study of deoxybenzoins on relaxing effects of porcine coronary artery. PubMed: Antioxidant and antimelanogenic properties of chestnut flower extract. PubMed: Enzymatic synthesis and characterization of hydroquinone galactoside using Kluyveromyces lactis lactase. PubMed: Phenolic Antioxidants from the Leaves of Camellia pachyandra Hu. PubMed: Anti-inflammatory, antioxidant, anti-tyrosinase and phenolic contents of four Podocarpus species used in traditional medicine in South Africa. PubMed: Inhibitory effects of hinokitiol on tyrosinase activity and melanin biosynthesis and its antimicrobial activities. PubMed: Growth-sensitive gold nanoshells precursor nanocomposites for the detection of L-DOPA and tyrosinase activity. PubMed: Ecklonia cava extracts inhibit lipopolysaccharide induced inflammatory responses in human endothelial cells. PubMed: Immobilization of tyrosinase in carboxylic and carbonyl group-modified MWNT electrode and its application for sensing phenolics in red wines. PubMed: Tyrosinase inhibitory constituents from the roots of Morus nigra: a structure-activity relationship study. PubMed: Inhibitory effect of diphlorethohydroxycarmalol on melanogenesis and its protective effect against UV-B radiation-induced cell damage. PubMed: Digestibility and allergenicity assessment of enzymatically crosslinked beta-casein. PubMed: Mushroom tyrosinase in polyelectrolyte multilayers as an optical biosensor for o-diphenols. PubMed: Nanofibrous membrane based tyrosinase-biosensor for the detection of phenolic compounds. PubMed: Inhibition of melanogensis by a novel origanoside from Origanum vulgare. PubMed: Phenolic inhibitors of chemical and enzymatic oxidation in the leaves of Myrica rubra. PubMed: Acetylcholinesterase, butyrylcholinesterase, and tyrosinase inhibition studies and antioxidant activities of 33 Scutellaria L. taxa from Turkey. PubMed: Picolyl alkyl amines as novel tyrosinase inhibitors: influence of hydrophobicity and substitution. PubMed: Isolation, cloning and characterization of a tyrosinase with improved activity in organic solvents from Bacillus megaterium. PubMed: Protective effects of tea polysaccharides and polyphenols on skin. PubMed: Optimization of antioxidant activity by response surface methodology in hydrolysates of jellyfish (Rhopilema esculentum) umbrella collagen. PubMed: Effects of selected organo-sulfur compounds on melanin formation. PubMed: Chemical components and tyrosinase inhibitors from the twigs of Artocarpus heterophyllus. PubMed: Phloridzin-induced melanogenesis is mediated by the cAMP signaling pathway. PubMed: Biosensors for phenolic compounds by immobilization of tyrosinase in photocurable methacrylic-acrylic membranes of varying hydrophilicities. PubMed: Determination of an antioxidant capacity index by immobilized tyrosinase bioreactor. PubMed: Characterization of the post-harvest changes in gene transcription in the gill of the Lentinula edodes fruiting body. PubMed: Antityrosinase and antimicrobial activities of trans-cinnamaldehyde thiosemicarbazone. PubMed: The tyrosinase-encoding gene of Lentinula edodes, Letyr, is abundantly expressed in the gills of the fruit-body during post-harvest preservation. PubMed: Inhibitory effect of phlorotannins isolated from Ecklonia cava on mushroom tyrosinase activity and melanin formation in mouse B16F10 melanoma cells. PubMed: Effect of ionizing radiation on the physiological activities of ethanol extract from hizikia fusiformis cooking drips. PubMed: Inhibitory effects of methyl trans-cinnamate on mushroom tyrosinase and its antimicrobial activities. PubMed: Fluorescence detection of tyrosinase activity on dopamine-betaxanthin purified from Portulaca oleracea (common purslane) flowers. PubMed: Tyrosinase inhibitory polyphenols from roots of Morus lhou. PubMed: Identification of an Alkylhydroquinone from Rhus succedanea as an Inhibitor of Tyrosinase and Melanogenesis. PubMed: Phenolic antioxidants from green tea produced from Camellia crassicolumna Var. multiplex. PubMed: Ecklonia cava ethanolic extracts inhibit lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in BV2 microglia via the MAP kinase and NF-kappaB pathways. PubMed: Rosmarinic acid, a photo-protective agent against UV and other ionizing radiations. PubMed: Comparative analysis of quercetin oxidation by electrochemical, enzymatic, autoxidation, and free radical generation techniques: a mechanistic study. PubMed: A second proPO present in white shrimp Litopenaeus vannamei and expression of the proPOs during a Vibrio alginolyticus injection, molt stage, and oral sodium alginate ingestion. PubMed: Chitosan-based tyrosinase optical phenol biosensor employing hybrid nafion/sol-gel silicate for MBTH immobilization. PubMed: Design of a composite amperometric enzyme electrode for the control of the benzoic acid content in food. PubMed: Effects of Gold Nanoparticles on the Response of Phenol Biosensor Containing Photocurable Membrane with Tyrosinase. PubMed: A comparison of three amperometric phenoloxidase-Sonogel-Carbon based biosensors for determination of polyphenols in beers. PubMed: Optimization of tyrosinase inhibition activity of ultrasonic-extracted polysaccharides from longan fruit pericarp. PubMed: Isolation of tyrosinase inhibitors from Artocarpus heterophyllus and use of its extract as antibrowning agent. PubMed: Phenolic antioxidants from green tea produced from Camellia taliensis. PubMed: Antibrowning activity of MRPs in enzyme and fresh-cut apple slice models. PubMed: Enzyme, protein, carbohydrate, and phenolic contaminants in commercial tyrosinase preparations: potential problems affecting tyrosinase activity and inhibition studies. PubMed: The anti-melanogenic effect of pycnogenol by its anti-oxidative actions. PubMed: Molecular and physical characteristics of squid (Todarodes pacificus) skin collagens and biological properties of their enzymatic hydrolysates. PubMed: Inhibitory effects of cinnamic acid on melanin biosynthesis in skin. PubMed: PPAR gamma regulates MITF and beta-catenin expression and promotes a differentiated phenotype in mouse melanoma S91. PubMed: Formation of protein-oligosaccharide conjugates by laccase and tyrosinase. PubMed: Inhibitory effects of kurarinol, kuraridinol, and trifolirhizin from Sophora flavescens on tyrosinase and melanin synthesis. PubMed: Identification of geranic acid, a tyrosinase inhibitor in lemongrass (Cymbopogon citratus). PubMed: A review on spectrophotometric methods for measuring the monophenolase and diphenolase activities of tyrosinase. PubMed: Immobilised tyrosinase-based biosensor for the detection of tea polyphenols. PubMed: Dual laccase-tyrosinase based Sonogel-Carbon biosensor for monitoring polyphenols in beers. PubMed: A thioredoxin of Sinorhizobium meliloti CE52G is required for melanin production and symbiotic nitrogen fixation. PubMed: Inhibition of the formation of the neurotoxin 5-S-cysteinyl-dopamine by polyphenols. PubMed: Melanogenesis inhibition by an oolong tea extract in b16 mouse melanoma cells and UV-induced skin pigmentation in brownish guinea pigs. PubMed: Tissue culture of some lichens and screening of their antioxidant, antityrosinase and antibacterial properties. PubMed: Naturally occurring tyrosinase inhibitors: mechanism and applications in skin health, cosmetics and agriculture industries. PubMed: Elucidating the mechanism of laccase and tyrosinase in wheat bread making. PubMed: Establishment of high-resolution FISH mapping system and its application for molecular cytogenetic characterization of chromosomes in newt, Cynops pyrrhogaster (Urodela, Amphibia). PubMed: Stereospecificity of mushroom tyrosinase immobilized on a chiral and a nonchiral support. PubMed: Antioxidant activity, anti-inflammatory activity, and whitening effects of extracts of Elaeagnus multiflora Thunb. PubMed: Enzymatic determination of BPA by means of tyrosinase immobilized on different carbon carriers. PubMed: Antioxidant and antimelanogenic activities of polyamine conjugates from corn bran and related hydroxycinnamic acids. PubMed: Oxyresveratrol as an antibrowning agent for cloudy apple juices and fresh-cut apples. PubMed: Two potent suicide substrates of mushroom tyrosinase: 7,8,4'-trihydroxyisoflavone and 5,7,8,4'-tetrahydroxyisoflavone. PubMed: Characterization of the activity of tyrosinase on betanidin. PubMed: Tyrosinase-aided protein cross-linking: effects on gel formation of chicken breast myofibrils and texture and water-holding of chicken breast meat homogenate gels. PubMed: Novel peptides with tyrosinase inhibitory activity. PubMed: Identification and kinetic study of tyrosinase inhibitors found in sake lees. PubMed: Free radical scavenging, anti-glycation and tyrosinase inhibition properties of a polysaccharide fraction isolated from the rind from Punica granatum. PubMed: Evaluation of free radical scavenging and antityrosinase activities of standardized longan fruit extract. PubMed: Synthesis, discovery and mechanism of 2,6-dimethoxy-N-(4-methoxyphenyl)benzamide as potent depigmenting agent in the skin. PubMed: Biosensor measurements of polar phenolics for the assessment of the bitterness and pungency of virgin olive oil. PubMed: Tyrosinase inhibitory activity of citrus essential oils. PubMed: Isolation and Characterization of Strain MMB-1 (CECT 4803), a Novel Melanogenic Marine Bacterium. PubMed: Hen egg white lysozyme as an inhibitor of mushroom tyrosinase. PubMed: Inhibitory effects of cis- and trans-isomers of 3,5-dihydroxystilbene on the activity of mushroom tyrosinase. PubMed: Flavonoids as mushroom tyrosinase inhibitors: a fluorescence quenching study. PubMed: Fungal tyrosinases: new prospects in molecular characteristics, bioengineering and biotechnological applications. PubMed: Characterization of the activity of tyrosinase on betaxanthins derived from (R)-amino acids. PubMed: Remodeling of actin cytoskeleton in lupeol-induced B16 2F2 cell differentiation. PubMed: Chemometric exploration of an amperometric biosensor array for fast determination of wastewater quality. PubMed: Physiological activity of irradiated green tea polyphenol on the human skin. PubMed: Isolation and identification of flavonoids in licorice and a study of their inhibitory effects on tyrosinase. PubMed: Effects of mushroom tyrosinase on anisaldehyde. PubMed: Iron and copper metabolism. PubMed: Inhibition of enzyme activities and the antiwrinkle effect of polyphenol isolated from the persimmon leaf (Diospyros kaki folium) on human skin. PubMed: Procyanidin trimers to pentamers fractionated from apple inhibit melanogenesis in B16 mouse melanoma cells. PubMed: Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future. PubMed: DPPH radical-scavenging compounds from dou-chi, a soybean fermented food. PubMed: Mushroom tyrosinase: catalase activity, inhibition, and suicide inactivation. PubMed: Characterization of a new tyrosinase from Pycnoporus species with high potential for food technological applications. PubMed: Tyrosinase inhibitors isolated from the edible brown alga Ecklonia stolonifera. PubMed: Effect of simultaneous administration of vitamin C, L-cysteine and vitamin E on the melanogenesis. PubMed: Anticancer therapeutic potential of soy isoflavone, genistein. PubMed: A sphingolipid and tyrosinase inhibitors from the fruiting body of Phellinus linteus. PubMed: In vitro antioxidative effects and tyrosinase inhibitory activities of seven hydroxycinnamoyl derivatives in green coffee beans. PubMed: Chalcones as potent tyrosinase inhibitors: the effect of hydroxyl positions and numbers. PubMed: Maillard reaction and enzymatic browning affect the allergenicity of Pru av 1, the major allergen from cherry (Prunus avium). PubMed: Enzymatic grafting of peptides from casein hydrolysate to chitosan. Potential for value-added byproducts from food-processing wastes. PubMed: Constituents of the leaves of Peucedanum japonicum Thunb. and their biological activity. PubMed: Inhibitory effect of 4-cyanobenzaldehyde and 4-cyanobenzoic acid on mushroom (Agaricus bisporus) tyrosinase. PubMed: Biosensors for determination of total and natural antioxidant capacity of red and white wines: comparison with other spectrophotometric and fluorimetric methods. PubMed: Kinetic study of the oxidation of quercetin by mushroom tyrosinase. PubMed: Tyrosinase inhibitory activity of cucumber compounds: enzymes responsible for browning in cucumber. PubMed: Tyrosinase inhibitor from black rice bran. PubMed: Tyrosinase inhibition kinetics of anisic acid. PubMed: Toxicity of melanin-free ink of Sepia officinalis to transformed cell lines: identification of the active factor as tyrosinase. PubMed: Inhibitory effect of red koji extracts on mushroom tyrosinase. PubMed: Enzyme-catalyzed gel formation of gelatin and chitosan: potential for in situ applications. PubMed: Mushroom tyrosinase: recent prospects. PubMed: Inhibition of diphenolase activity of tyrosinase by vitamin b(6) compounds. PubMed: Inhibitory effects of (S)- and (R)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acids on tyrosinase activity. PubMed: Glabrene and isoliquiritigenin as tyrosinase inhibitors from licorice roots. PubMed: Tyrosinase inhibition: general and applied aspects. PubMed: Biosensors designed for environmental and food quality control based on screen-printed graphite electrodes with different configurations. PubMed: Kinetics of mushroom tyrosinase inhibition by quercetin. PubMed: Diphenol activation of the monophenolase and diphenolase activities of field bean (Dolichos lablab) polyphenol oxidase. PubMed: Tyrosinase inhibitors of Pulsatilla cernua root-derived materials. PubMed: Two OPEEs (organic phase enzyme electrodes) used to check the percentage water content in hydrophobic foods and drugs. PubMed: Oxidation of polyphenols in phytate-reduced high-tannin cereals: effect on different phenolic groups and on in vitro accessible iron. PubMed: Mercaptan-capturing properties of mushrooms. PubMed: Detection of Campylobacter jejuni in poultry samples using an enzyme-linked immunoassay coupled with an enzyme electrode. PubMed: Competitive inhibition of mushroom tyrosinase by 4-substituted benzaldehydes. PubMed: Oxidation of bisphenol A and related compounds. PubMed: An optical biosensor employing tiron-immobilised polypyrrole films for estimating monophenolase activity in apple juice. PubMed: Effects of wine phenolics and sorghum tannins on tyrosinase activity and growth of melanoma cells. PubMed: Resveratrol and a novel tyrosinase in Carignan grape juice. PubMed: Synthesis of the antioxidant hydroxytyrosol using tyrosinase as biocatalyst. PubMed: Rapid detection of Salmonella typhimurium in chicken carcass wash water using an immunoelectrochemical method. PubMed: Characterization of tyrosinase- and polyphenol esterase-catalyzed end products using selected phenolic substrates. PubMed: Molecular design of antibrowning agents. PubMed: Comparison among differential pulse voltammetry, amperometric biosensor, and HPLC/DAD analysis for polyphenol determination. PubMed: Enzymatic assay for the determination of olive oil polyphenol content: assay conditions and validation of the method. PubMed: Activation of a latent mushroom (Agaricus bisporus) tyrosinase isoform by sodium dodecyl sulfate (SDS). Kinetic properties of the SDS-activated isoform. PubMed: Kinetic study of the activation process of a latent mushroom (Agaricus bisporus) tyrosinase by serine proteases. PubMed: Kinetics of activation of latent mushroom (Agaricus bisporus) tyrosinase by benzyl alcohol. PubMed: Kinetic study of the oxidation of gamma-L-glutaminyl-4-hydroxybenzene catalyzed by mushroom (Agaricus bisporus) tyrosinase. PubMed: Slow-binding inhibition of mushroom (Agaricus bisporus) tyrosinase isoforms by tropolone. PubMed: Tyrosinase inhibitory activity of the olive oil flavor compounds. PubMed: Flavonols from saffron flower: tyrosinase inhibitory activity and inhibition mechanism. PubMed: Characterization of tyrosinase from the cap flesh of portabella mushrooms. PubMed: Effect of baking and freeze-drying on the direct and indirect mutagenicity of extracts from the edible mushroom Agaricus bisporus. PubMed: N-acetyl-L-tyrosine (NAT) as a substrate for mushroom tyrosinase. PubMed: Silk protein, sericin, inhibits lipid peroxidation and tyrosinase activity. PubMed: Adjuvant therapy of malignant melanoma. PubMed: Effect of maltol on the oxidation of DL-DOPA, dopamine, N-acetyldopamine (NADA), and norepinephrine by mushroom tyrosinase. PubMed: Purification and properties of tyrosinase isozymes from the gill of Lentinus edodes fruiting body. PubMed: Inhibition of polyphenol oxidase by copper-metallothionein from Aspergillus niger. PubMed: Inhibition of rat, mouse, and human glutathione S-transferase by eugenol and its oxidation products. PubMed: Effect of kojic acid on the oxidation of DL-DOPA, norepinephrine, and dopamine by mushroom tyrosinase. PubMed: Contribution of phenolic and quinonoid structures in the mutagenicity of the edible mushroom Agaricus bisporus. PubMed: Modulation by ascorbic acid of the cutaneous and hepatic biochemical effects induced by topically applied benzanthrone in mice. PubMed: Liquid chromatographic separation of phenolic drugs using catalytic detection: comparison of an enzyme reactor and enzyme electrode. PubMed: Effect of different isomers of dihydroxybenzoic acids (DBA) on the rate of DL-dopa oxidation by mushroom tyrosinase. PubMed: Synergism exerted by 4-methyl catechol, catechol, and their respective quinones on the rate of DL-DOPA oxidation by mushroom tyrosinase. PubMed: Inactivation of metalloenzymes by food constituents. PubMed: Inactivation of metalloenzymes by lysinoalanine, phenylethylaminoalanine, alkali-treated food proteins, and sulfur amino acids. PubMed: Stability of tryptophan during food processing and storage. 1. Comparative losses of tryptophan, lysine and methionine in different model systems. PubMed: Inactivation of quercetin mutagenicity. PubMed: Factors which facilitate inactivation of quercetin mutagenicity. PubMed: Molecular basis of substrate and inhibitory specificity of tyrosinase: phenolic compounds. PubMed: Functional significance of the crystal cells in the larva of Drosophila melanogaster. PubMed: Oxidising enzymes: The relationship of oxygenase to tyrosinase.