uncaria rhynchophylla extract

extract of the splinter of the uncaria rhynchophylla, rubiaceae nauclea rhynchophylla extract ourouparia rhynchophylla extract uncaria rhynchophylla var. kouteng extract PubMed: Colletotrilactam A-D, novel lactams from Colletotrichum gloeosporioides GT-7, a fungal endophyte of Uncaria rhynchophylla. PubMed: Gastrodia and Uncaria (tianma gouteng) water extract exerts antioxidative and antiapoptotic effects against cerebral ischemia in vitro and in vivo. PubMed: Molecular evaluation of herbal compounds as potent inhibitors of acetylcholinesterase for the treatment of Alzheimer's disease. PubMed: Evaluation and application of a mixed-mode chromatographic stationary phase in two-dimensional liquid chromatography for the separation of traditional Chinese medicine. PubMed: Pharmacokinetic study of isocorynoxeine metabolites mediated by cytochrome P450 enzymes in rat and human liver microsomes. PubMed: Two new ortho benzoquinones from Uncaria rhynchophylla. PubMed: [Effect of Baichanting Compound on Dopamine Contents in Parkinson's Disease Model Mice]. PubMed: Boosting Sensitivity in Liquid Chromatography-Fourier Transform Ion Cyclotron Resonance-Tandem Mass Spectrometry for Product Ion Analysis of Monoterpene Indole Alkaloids. PubMed: Rhynchophylline Protects Against the Amyloid β-Induced Increase of Spontaneous Discharges in the Hippocampal CA1 Region of Rats. PubMed: Protective effects on vascular endothelial cell in N'-nitro-L-arginine (L-NNA)-induced hypertensive rats from the combination of effective components of Uncaria rhynchophylla and Semen Raphani. PubMed: An efficient and target-oriented sample enrichment method for preparative separation of minor alkaloids by pH-zone-refining counter-current chromatography. PubMed: Identification of Aroma-active Compounds in Essential Oil from Uncaria Hook by Gas Chromatography- Mass Spectrometry and Gas Chromatography-Olfactometry. PubMed: Metabolic Profile of Isocorynoxeine in Rats Obtained by Ultra-High Performance Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry. PubMed: An integrated strategy for the systematic characterization and discovery of new indole alkaloids from Uncaria rhynchophylla by UHPLC/DAD/LTQ-Orbitrap-MS. PubMed: Geissoschizine methyl ether N-oxide, a new alkaloid with antiacetylcholinesterase activity from Uncaria rhynchophylla. PubMed: De novo transcriptome sequencing and digital gene expression analysis predict biosynthetic pathway of rhynchophylline and isorhynchophylline from Uncaria rhynchophylla, a non-model plant with potent anti-alzheimer's properties. PubMed: Isorhynchophylline improves learning and memory impairments induced by D-galactose in mice. PubMed: Isorhynchophylline protects against pulmonary arterial hypertension and suppresses PASMCs proliferation. PubMed: Determination of protein-unbound rhynchiphylline brain distribution by microdialysis and ultra-performance liquid chromatography with tandem mass spectrometry. PubMed: Inhibitory effect of rhynchophylline on contraction of cerebral arterioles to endothelin 1: role of rho kinase. PubMed: Development of LC-MS determination method and back-propagation ANN pharmacokinetic model of corynoxeine in rat. PubMed: New triterpenic acids from Uncaria rhynchophylla: chemistry, NO-inhibitory activity, and tandem mass spectrometric analysis. PubMed: Uncaria rhynchophylla and rhynchophylline improved kainic acid-induced epileptic seizures via IL-1β and brain-derived neurotrophic factor. PubMed: Corynoxine, a natural autophagy enhancer, promotes the clearance of alpha-synuclein via Akt/mTOR pathway. PubMed: Antiepileptic Effect of Uncaria rhynchophylla and Rhynchophylline Involved in the Initiation of c-Jun N-Terminal Kinase Phosphorylation of MAPK Signal Pathways in Acute Seizures of Kainic Acid-Treated Rats. PubMed: Isorhynchophylline Protects PC12 Cells Against Beta-Amyloid-Induced Apoptosis via PI3K/Akt Signaling Pathway. PubMed: Isorhynchophylline treatment improves the amyloid-β-induced cognitive impairment in rats via inhibition of neuronal apoptosis and tau protein hyperphosphorylation. PubMed: Determination of rhynchophylline and hirsutine in rat plasma by UPLC-MS/MS after oral administration of Uncaria rhynchophylla extract. PubMed: Ameliorating effect of new constituents from the hooks of Uncaria rhynchophylla on scopolamine-induced memory impairment. PubMed: Rhynchophylline-induced vasodilation in human mesenteric artery is mainly due to blockage of L-type calcium channels in vascular smooth muscle cells. PubMed: [Determination of rhynchophylline and isorhynchophylline in Uncaria rhynchophylla by HPLC]. PubMed: Systematic identification and quantification of tetracyclic monoterpenoid oxindole alkaloids in Uncaria rhynchophylla and their fragmentations in Q-TOF-MS spectra. PubMed: Plant-based medicines for anxiety disorders, Part 1: a review of preclinical studies. PubMed: A review on indole alkaloids isolated from Uncaria rhynchophylla and their pharmacological studies. PubMed: Prostate cell membrane chromatography-liquid chromatography-mass spectrometry for screening of active constituents from Uncaria rhynchophylla. PubMed: Hirsutine, an indole alkaloid of Uncaria rhynchophylla, inhibits inflammation-mediated neurotoxicity and microglial activation. PubMed: Bioassay-Guided Isolation of Neuroprotective Compounds from Uncaria rhynchophylla against Beta-Amyloid-Induced Neurotoxicity. PubMed: Rhynchophylline attenuates LPS-induced pro-inflammatory responses through down-regulation of MAPK/NF-κB signaling pathways in primary microglia. PubMed: Comparative study of fourteen alkaloids from Uncaria rhynchophylla hooks and leaves using HPLC-diode array detection-atmospheric pressure chemical ionization/MS method. PubMed: Isorhynchophylline, a natural alkaloid, promotes the degradation of alpha-synuclein in neuronal cells via inducing autophagy. PubMed: Protective effect of isorhynchophylline against β-amyloid-induced neurotoxicity in PC12 cells. PubMed: Uncaria rhynchophylla ameliorates cognitive deficits induced by D-galactose in mice. PubMed: Phytochemical characteristics, free radical scavenging activities, and neuroprotection of five medicinal plant extracts. PubMed: Neuroprotective Effect of Uncaria rhynchophylla in Kainic Acid-Induced Epileptic Seizures by Modulating Hippocampal Mossy Fiber Sprouting, Neuron Survival, Astrocyte Proliferation, and S100B Expression. PubMed: Traditional Chinese medicines and Alzheimer's disease. PubMed: Geissoschizine methyl ether, a corynanthean-type indole alkaloid from Uncaria rhynchophylla as a potential acetylcholinesterase inhibitor. PubMed: Uncarinic Acid C Isolated from Uncaria rhynchophylla Induces Differentiation of Th1-Promoting Dendritic Cells Through TLR4 Signaling. PubMed: Oral Uncaria rhynchophylla (UR) reduces kainic acid-induced epileptic seizures and neuronal death accompanied by attenuating glial cell proliferation and S100B proteins in rats. PubMed: Protective effects of isorhynchophylline on cardiac arrhythmias in rats and guinea pigs. PubMed: Protective effects of novel single compound, Hirsutine on hypoxic neonatal rat cardiomyocytes. PubMed: Uncarinic acid C plus IFN-γ generates monocyte-derived dendritic cells and induces a potent Th1 polarization with capacity to migrate. PubMed: Uncaria rhynchophylla inhibits the production of nitric oxide and interleukin-1β through blocking nuclear factor κB, Akt, and mitogen-activated protein kinase activation in macrophages. PubMed: Use of Yokukansan (TJ-54) in the treatment of neurological disorders: a review. PubMed: Uncaria rhynchophylla upregulates the expression of MIF and cyclophilin A in kainic acid-induced epilepsy rats: A proteomic analysis. PubMed: Ursolic acid isolated from Uncaria rhynchophylla activates human dendritic cells via TLR2 and/or TLR4 and induces the production of IFN-gamma by CD4+ naïve T cells. PubMed: Triterpene esters from Uncaria rhynchophylla drive potent IL-12-dependent Th1 polarization. PubMed: Metabolism and pharmacokinetics of rhynchophylline in rats. PubMed: Uncaria rhynchophylla (miq) Jack plays a role in neuronal protection in kainic acid-treated rats. PubMed: Effects of rhynchophylline and isorhynchophylline on nitric oxide and endothelin-1 secretion from RIMECs induced by Listeriolysin O in vitro. PubMed: Anti-inflammatory effects of rhynchophylline and isorhynchophylline in mouse N9 microglial cells and the molecular mechanism. PubMed: Effects of the hook of Uncaria rhynchophylla on neurotoxicity in the 6-hydroxydopamine model of Parkinson's disease. PubMed: Uncaria rhynchophylla and Rhynchophylline inhibit c-Jun N-terminal kinase phosphorylation and nuclear factor-kappaB activity in kainic acid-treated rats. PubMed: Rhynchophylline from Uncaria rhynchophylla functionally turns delayed rectifiers into A-Type K+ channels. PubMed: Corynoxeine isolated from the hook of Uncaria rhynchophylla inhibits rat aortic vascular smooth muscle cell proliferation through the blocking of extracellular signal regulated kinase 1/2 phosphorylation. PubMed: Structure-activity relationship of pentacylic triterpene esters from Uncaria rhynchophylla as inhibitors of phospholipase Cgamma1. PubMed: Alkaloids from the leaves of Uncaria rhynchophylla and their inhibitory activity on NO production in lipopolysaccharide-activated microglia. PubMed: Methanolic extracts of Uncaria rhynchophylla induce cytotoxicity and apoptosis in HT-29 human colon carcinoma cells. PubMed: [Effects of combined use of total alkaloids of Uncaria rhynchophylla and Coryadlis ambailis migo on cerebral ischemia-reperfusion injury in rats]. PubMed: [Contents mensuration of total alkaloid in Uncaria rhynchophylla by acid dye colorimetry]. PubMed: [Protective effect of Uncaria rhynchophylla total alkaloids pretreatment on hippocampal neurons after acute hypoxia]. PubMed: Metabolites of hirsuteine and hirsutine, the major indole alkaloids of Uncaria rhynchophylla, in rats. PubMed: [Identification study of Mongolian herbal medicine Rubus Sachalinesis Leveille and its forgeries by UV/fluorescence/IR spectroscopy]. PubMed: Anxiolytic effects of the aqueous extract of Uncaria rhynchophylla. PubMed: Uncaria rhynchophylla, a Chinese medicinal herb, has potent antiaggregation effects on Alzheimer's beta-amyloid proteins. PubMed: Uncaria rhynchophylla induces angiogenesis in vitro and in vivo. PubMed: Monoamine oxidase B (MAO-B) inhibition by active principles from Uncaria rhynchophylla. PubMed: Inhibition of monoamine oxidase B (MAO-B) by Chinese herbal medicines. PubMed: In vitro vasodilator mechanisms of the indole alkaloids rhynchophylline and isorhynchophylline, isolated from the hook of Uncaria rhynchophylla (Miquel). PubMed: [TLC-FT-SERS study on ingredients of Isrhynchophylline]. PubMed: Alkaloid fraction of Uncaria rhynchophylla protects against N-methyl-D-aspartate-induced apoptosis in rat hippocampal slices. PubMed: Protective effect of methanol extract of Uncaria rhynchophylla against excitotoxicity induced by N-methyl-D-aspartate in rat hippocampus. PubMed: N-methyl-D-aspartate receptor antagonist activity in traditional Chinese stroke medicines. PubMed: Pharmacological actions of Uncaria alkaloids, rhynchophylline and isorhynchophylline. PubMed: Neuroprotection by methanol extract of Uncaria rhynchophylla against global cerebral ischemia in rats. PubMed: Inhibition of phospholipase cgamma1 and cancer cell proliferation by triterpene esters from Uncaria rhynchophylla. PubMed: Active-oxygen scavenging activity of traditional nourishing-tonic herbal medicines and active constituents of Rhodiola sacra. PubMed: Effects of hirsutine and dihydrocorynantheine on the action potentials of sino-atrial node, atrium and ventricle. PubMed: Anticonvulsive and free radical scavenging actions of two herbs, Uncaria rhynchophylla (MIQ) Jack and Gastrodia elata Bl., in kainic acid-treated rats. PubMed: Anticonvulsant effect of Uncaria rhynchophylla (Miq) Jack. in rats with kainic acid-induced epileptic seizure. PubMed: Effect on locomotion of indole alkaloids from the hooks of uncaria plants. PubMed: Uncarinic acids: phospholipase Cgamma1 inhibitors from hooks of Uncaria rhynchophylla. PubMed: Application of radioligand receptor binding assays in the search for CNS active principles from Chinese medicinal plants. PubMed: Studies on Taiwan folk medicine, thang-kau-tin (II): Measurement of active oxygen scavenging activity using an ESR technique. PubMed: Gou-teng (from Uncaria rhynchophylla Miquel)-induced endothelium-dependent and -independent relaxations in the isolated rat aorta. PubMed: Antioxidant and free radical scavenging activities of Gastrodia elata Bl. and Uncaria rhynchophylla (Miq.) Jacks. PubMed: Effects of hirsutine, an antihypertensive indole alkaloid from Uncaria rhynchophylla, on intracellular calcium in rat thoracic aorta. PubMed: Method of Harvesting the Crude Drug Based on Distribution of Alkaloids in the Hook and in the Stem with Hook of Uncaria rhynchophylla1. PubMed: [Vasodilative effects of indole alkaloids obtained from domestic plants, Uncaria rhynchophylla Miq. and Amsonia elliptica Roem. et Schult]. PubMed: [Pharmacological studies of indole alkaloids obtained from domestic plants, Uncaria rhynchophylla Miq. and Amsonia elliptica Roem. et Schult]. PubMed: [Studies of plants containing indole alkaloids. IX. Quantitative analysis of tertiary alkaloids in various parts of Uncaria rhynchophylla MIQ]. PubMed: [The antihypertensive effect of Uncaria rhynchophylla in essential hypertension (author's transl)]. PubMed: Effects of indole alkaloids from Gardneria nutans Sieb. et Zucc. and Uncaria rhynchophylla Miq. on a guinea pig urinary bladder preparation in situ. PubMed: [Studies of plants containing indole alkaloids. 2. On the alkaloids of Uncaria rhynchophylla Miq].