toddaculin
2H-1-benzopyran-2-one, 5,7-dimethoxy-6-(3-methyl-2-butenyl)-
Identification
| Name | toddaculin |
| IUPAC | 5,7-dimethoxy-6-(3-methylbut-2-enyl)chromen-2-one |
| CAS Number | 4335-12-0 |
| FDA UNII | Search |
| Molecular Formula | C16 H18 O4 |
| Molecular Weight | 274.31626000 |
| Nikkaji Number | J13.504F |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 432.81 °C. @ 760.00 mm Hg (est) |
| Flash Point | 378.00 °F. TCC ( 192.20 °C. ) (est) |
| logP (o/w) | 4.151 (est) |
| Soluble in | water, 6.277 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for toddaculin usage levels up to | not for fragrance use. |
| Recommendation for toddaculin flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
2H-1-
benzopyran-2-one, 5,7-dimethoxy-6-(3-methyl-2-butenyl)-
5,7-
dimethoxy-6-(3-methyl-2-butenyl)-2H-1-benzopyran-2-one
5,7-
dimethoxy-6-(3-methylbut-2-enyl)chromen-2-one
toddaculine
PubMed:
Toddaculin, Isolated from of Toddalia asiatica (L.) Lam., Inhibited Osteoclastogenesis in RAW 264 Cells and Enhanced Osteoblastogenesis in MC3T3-E1 Cells.
PubMed:
Anti-inflammatory activity of omphalocarpin isolated from Radix Toddaliae Asiaticae.
PubMed:
Toddaculin, a natural coumarin from Toddalia asiatica, induces differentiation and apoptosis in U-937 leukemic cells.
PubMed:
[Studies on the chemical constituents of Rutaceae++ plants. LXVI. The chemical constituents of Toddalia asiatica (L.) Lam. (T. aculeata Pers.). (1). Chemical constituents of the root bark].