piperitenone oxide
1-methyl-4-propan-2-ylidene-7-oxabicyclo[4.1.0]heptan-5-one
Identification
| Name | piperitenone oxide |
| IUPAC | 1-methyl-4-propan-2-ylidene-7-oxabicyclo[4.1.0]heptan-5-one |
| CAS Number | 35178-55-3 |
| FDA UNII | Search |
| Molecular Formula | C10 H14 O2 |
| Molecular Weight | 166.21998000 |
| Nikkaji Number | J373.722E |
| CoE Number | 10508 |
Regulatory
| JECFA Food Flavoring | 1574 piperitenone oxide |
| FEMA Number | 4199 |
| FDA | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF) | 35178-55-3 ; PIPERITENONE OXIDE |
| FDA Regulation | FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION |
Physical Properties
| Appearance | colorless solid (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 25.00 °C. @ 760.00 mm Hg |
| Boiling Point | 255.00 to 256.00 °C. @ 760.00 mm Hg |
| Acid Value | 1.00 max. KOH/g |
| Vapor Pressure | 0.016000 mmHg @ 25.00 °C. (est) |
| Flash Point | 225.00 °F. TCC ( 107.22 °C. ) |
| logP (o/w) | 0.754 (est) |
| Soluble in | alcohol |
Organoleptic Properties
| Odor Description | at 10.00 % in dipropylene glycol. |
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | flavoring agents |
| Recommendation for piperitenone oxide usage levels up to | not for fragrance use. |
| Maximised Survey-derived Daily Intakes (MSDI-EU) | 0.012 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA) | 0.20 (μg/capita/day) |
| Structure Class | III |
| baked goods | 3.00000 |
| beverages(nonalcoholic) | - |
| beverages(alcoholic) | - |
| breakfast cereal | 2.00000 |
| cheese | 2.00000 |
| chewing gum | - |
| condiments / relishes | 5.00000 |
| confectionery froastings | - |
| egg products | 2.00000 |
| fats / oils | 2.00000 |
| fish products | 3.00000 |
| frozen dairy | 5.00000 |
| fruit ices | 1.00000 |
| gelatins / puddings | - |
| granulated sugar | - |
| gravies | - |
| hard candy | - |
| imitation dairy | - |
| instant coffee / tea | - |
| jams / jellies | - |
| meat products | - |
| milk products | - |
| nut products | - |
| other grains | 3.00000 |
| poultry | - |
| processed fruits | 1.00000 |
| processed vegetables | - |
| reconstituted vegetables | - |
| seasonings / flavors | - |
| snack foods | - |
| soft candy | 2.00000 |
| soups | - |
| sugar substitutes | - |
| sweet sauces | - |
BOC Sciences
Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...
Chemical sources Association Inc
Exchange of knowledge
Need This Item for Flavor? You can contact the Chemical Sources Association.
Potential Uses
Natural Occurrence
Synonyms
7-oxa
bicyclo(4.1.0)heptan-2-one, 6-methyl-3-(1-methylethylidene)-
1,2-
epoxy-p-menth-4(8)-en-3-one
1,2-
epoxy-para-menth-4(8)-en-3-one
p-
menth-4(8)-en-3-one, 1,2-epoxy-
6-
methyl-3-(1-methyl ethylidene)-7-oxabicyclo(4.1.0)heptan-2-one
6-
methyl-3-(1-methylethylidene)-7-oxabicyclo(4.1.0)heptan-2-one
1-
methyl-4-propan-2-ylidene-7-oxabicyclo[4.1.0]heptan-5-one
rotundifolone
Info:
epoxides
PubMed:
Chemical composition and antimicrobial activity of the essential oil of Plectranthus mollis (Lamiaceae) from Western Ghats Region, Karnataka, India.
PubMed:
Discrimination of fennel chemotypes applying IR and Raman spectroscopy: discovery of a new γ-asarone chemotype.
PubMed:
In vitro inhibition of herpes simplex virus type 1 replication by Mentha suaveolens essential oil and its main component piperitenone oxide.
PubMed:
Antioxidant Activity and Volatile and Phenolic Profiles of Essential Oil and Different Extracts of Wild Mint (Mentha longifolia) from the Pakistani Flora.
PubMed:
Essential oils of Micromeria dalmatica Benth., a Balkan endemic species of section Pseudomelissa.
PubMed:
Biological activities of Eremostachys laevigata Bunge. grown in Iran.
PubMed:
In vitro production of M. Ã piperita not containing pulegone and menthofuran.
PubMed:
Essential-oil diversity of three Calamintha species from Greece.
PubMed:
Intraspecific variability of the essential oil of Calamintha nepeta subsp. nepeta from Southern Italy (Apulia).
PubMed:
Chemical and morphological diversity in wild populations of Mentha longifolia in Israel.
PubMed:
Composition of the essential oil of Origanum tyttanthum from Tajikistan.
PubMed:
Mentha longifolia in vitro cultures as safe source of flavouring ingredients.
PubMed:
HS-SPME-GCÃGC-qMS volatile metabolite profiling of Chrysolina herbacea frass and Mentha spp. leaves.
PubMed:
Comparative study of volatile oil compositions of two Plectranthus species from northern India.
PubMed:
Chemical composition and biological assays of essential oils of Calamintha nepeta (L.) Savi subsp. nepeta (Lamiaceae).
PubMed:
Seasonal variation in content, chemical composition and antimicrobial and cytotoxic activities of essential oils from four Mentha species.
PubMed:
Chemical composition and larvicidal evaluation of Mentha, Salvia, and Melissa essential oils against the West Nile virus mosquito Culex pipiens.
PubMed:
Composition and chemical variability of Mentha suaveolens ssp. suaveolens and M. suaveolens ssp. insularis from Corsica.
PubMed:
Chemical composition and antimicrobial and antioxidant activities of Mentha (longifolia L. and viridis) essential oils.
PubMed:
Antinociceptive effects of the essential oil of Mentha x villosa leaf and its major constituent piperitenone oxide in mice.
PubMed:
Comparative analysis of the oil and supercritical CO2 extract of Ridolfia segetum (L.) Moris.
PubMed:
Piperitenone oxide as toxic, repellent, and reproduction retardant toward malarial vector Anopheles stephensi (Diptera: Anophelinae).
PubMed:
Composition of the essential oil of Mentha microphylla from the Gennargentu Mountains (Sardinia, Italy).
PubMed:
Antibacterial and antifungal activity of essential oils of Mentha suaveolens.
PubMed:
Activity of essential oils of three Micromeria species (Lamiaceae) against micromycetes and bacteria.
PubMed:
Cardiovascular effects of the essential oil of Mentha x villosa and its main constituent, piperitenone oxide, in normotensive anaesthetised rats: role of the autonomic nervous system.
PubMed:
Phytochemical study of Mentha longifolia of Morocco.
PubMed:
Effects of piperitenone oxide on the intestinal smooth muscle of the guinea pig.
PubMed:
Microbial transformations of some monoterpenoids and sesquiterpenoids.