visnadine
butanoic acid, 2-methyl-, (9R,10R)-10-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-9-yl ester, (2R)-
Identification
| Name | visnadine |
| CAS Number | 477-32-7 |
| EINECS | 207-515-1 |
| FDA UNII | 0RL4V0K263 |
| Molecular Formula | C21 H24 O7 |
| Molecular Weight | 388.41668000 |
| Nikkaji Number | J67.394C |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 2.38 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intravenous-dog LDLo 20 mg/kg |
| Dermal Toxicity | subcutaneous-mouse LD50 > 370 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'LUNGS, THORAX, OR RESPIRATION: DYSPNEA\nBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD\nBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)', 'LUNGS, THORAX, OR RESPIRATION: DYSPNEA\nBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD\nBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)']
Safety in Use
| Category | cosmetic ingredient for skin conditioning |
| Recommendation for visnadine usage levels up to | not for fragrance use. |
| Recommendation for visnadine flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
[(9R,10R)-10-
acetyloxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl] (2R)-2-methylbutanoate
butanoic acid, 2-methyl-, (9R,10R)-10-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-9-yl ester, (2R)-
PubMed:
Randomized crossover study investigating daily versus on-demand vulvar Visnadine spray in women affected by female sexual arousal disorder.
PubMed:
Effects of visnadine on rat isolated vascular smooth muscles.
PubMed:
Study of the action of visnadine on general and cardiac hemodynamics.
PubMed:
[Coronary treatment with visnadine].
PubMed:
[Studies on the effect of the coronary active substance (Visnadine) on fat and carbohydrate metabolism].
PubMed:
[Clinical observations on the effect of Visnadine in acute myocardial lesions].
PubMed:
[The effect of Visnadine in chronic degenerative myocardial lesions].
PubMed:
[On the chemistry, pharmacology and toxicology of Visnadine].
PubMed:
[A further contribution to the study of biological effects of visnadine].
PubMed:
[VISNADINE IN THE TREATMENT OF MYOCARDIAL INFARCT AND CORONARY DISEASE].