zapotin

Export Excel
CAS: 14813-19-5 C19 H18 O6 MW: 342.34766000
All Ingredients Aromatic Ingredients CAS Numbers Flavor Ingredients Found in Nature

Identification

Namezapotin
CAS Number14813-19-5
FDA UNIISearch
Molecular FormulaC19 H18 O6
Molecular Weight342.34766000
Nikkaji NumberJ14.305G

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 10.17 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for zapotin usage levels up tonot for fragrance use.
Recommendation for zapotin flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

casimiroa edulis bark

Synonyms

2-(2,6- dimethoxyphenyl)-5,6-dimethoxychromen-4-one 5,6,2',6'- tetramethoxyflavone PubMed: Antidepressant-like effect of Casimiroa pubescens root extracts. PubMed: Zapotin (5,6,2',6'-tetramethoxyflavone) Modulates the Crosstalk Between Autophagy and Apoptosis Pathways in Cancer Cells with Overexpressed Constitutively Active PKCϵ. PubMed: The tetramethoxyflavone zapotin selectively activates protein kinase C epsilon, leading to its down-modulation accompanied by Bcl-2, c-Jun and c-Fos decrease. PubMed: Vasorelaxation by extracts of Casimiroa spp. in rat resistance vessels and pharmacological study of cellular mechanisms. PubMed: Zapotin prevents mouse skin tumorigenesis during the stages of initiation and promotion. PubMed: Zapotin, a phytochemical present in a Mexican fruit, prevents colon carcinogenesis. PubMed: Synthesis and cancer chemopreventive activity of zapotin, a natural product from Casimiroa edulis. PubMed: Lipophilic flavones of Primula veris L. from field cultivation and in vitro cultures. PubMed: Discovery of novel inducers of cellular differentiation using HL-60 promyelocytic cells. PubMed: Plant antitumor agents, 21. Flavones, coumarins, and an alkaloid from Sargentia greggii.