[6]-dehydrogingerdione
dehydro-6-gingerdione
Identification
| Name | [6]-dehydrogingerdione |
| CAS Number | 76060-35-0 |
| FDA UNII | Search |
| Molecular Formula | C17 H22 O4 |
| Molecular Weight | 290.35914000 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 24.44 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for [6]-dehydrogingerdione usage levels up to | not for fragrance use. |
| Recommendation for [6]-dehydrogingerdione flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
dehydro-6-gingerdione
6-
dehydrogingerdione
(1Z,3Z)-3-
hydroxy-1-(4-hydroxy-3-methoxyphenyl)deca-1,3-dien-5-one
PubMed:
Ginger Phytochemicals Inhibit Cell Growth and Modulate Drug Resistance Factors in Docetaxel Resistant Prostate Cancer Cell.
PubMed:
6-Dehydrogingerdione restrains lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages.
PubMed:
Anthelmintic constituents from ginger (Zingiber officinale) against Hymenolepis nana.
PubMed:
Activation of the phase II enzymes for neuroprotection by ginger active constituent 6-dehydrogingerdione in PC12 cells.
PubMed:
Enhancements of skin cell proliferations and migrations via 6-dehydrogingerdione.
PubMed:
Zingiber officinale (ginger) compounds have tetracycline-resistance modifying effects against clinical extensively drug-resistant Acinetobacter baumannii.
PubMed:
6-dehydrogingerdione sensitizes human hepatoblastoma Hep G2 cells to TRAIL-induced apoptosis via reactive oxygen species-mediated increase of DR5.
PubMed:
6-Dehydrogingerdione, an active constituent of dietary ginger, induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human breast cancer cells.
PubMed:
Mosquito larvicidal activity of isolated compounds from the rhizome of Zingiber officinale.
PubMed:
5-HT3 receptor blocking activity of arylalkanes isolated from the rhizome of Zingiber officinale.
PubMed:
Protective activities of some phenolic 1,3-diketones against lipid peroxidation: possible involvement of the 1,3-diketone moiety.
PubMed:
[Qualitative and quantitative analysis of bioactive principles in Zingiberis Rhizoma by means of high performance liquid chromatography and gas liquid chromatography. On the evaluation of Zingiberis Rhizoma and chemical change of constituents during Zingiberis Rhizoma processing].
PubMed:
[The effect of ginger on serotonin induced hypothermia and diarrhea].
PubMed:
Chemical structural requirement in gingerol derivatives for potentiation of prostaglandin F2 alpha-induced contraction in isolated mesenteric veins of mice.