farnesiferol C
Identification
| Name | farnesiferol C |
| CAS Number | 512-17-4 |
| FDA UNII | 56P18T724F |
| Molecular Formula | C24 H30 O4 |
| Molecular Weight | 382.49990000 |
| Nikkaji Number | J13.342F |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 0.02342 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for farnesiferol C usage levels up to | not for fragrance use. |
| Recommendation for farnesiferol C flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
7-[(E)-3-
methyl-5-[(1R,3R,4S)-2,2,4-trimethyl-7-oxabicyclo[2.2.1]heptan-3-yl]pent-2-enoxy]chromen-2-one
PubMed:
The inhibitory effect of farnesiferol C against catalase; Kinetics, interaction mechanism and molecular docking simulation.
PubMed:
Farnesiferol C induces cell cycle arrest and apoptosis mediated by oxidative stress in MCF-7 cell line.
PubMed:
Biological activities of farnesiferol C: a review.
PubMed:
In Silico and In Vitro Evaluation of Cytotoxic Activities of Farnesiferol C and Microlobin on MCF-7, HeLa and KYSE Cell Lines.
PubMed:
Farnesiferol c induces apoptosis via regulation of L11 and c-Myc with combinational potential with anticancer drugs in non-small-cell lung cancers.
PubMed:
Modulation of Multidrug Resistance Protein 2 Efflux in the Cisplatin Resistance Human Ovarian Carcinoma Cells A2780/RCIS by Sesquiterpene Coumarins.
PubMed:
Anti-proliferative and Apoptotic Effects of Dendrosomal Farnesiferol C on Gastric Cancer Cells.
PubMed:
Reversal of P-glycoprotein-mediated multidrug resistance in MCF-7/Adr cancer cells by sesquiterpene coumarins.
PubMed:
Bioactive sesquiterpene coumarins from Ferula pseudalliacea.
PubMed:
Galbanic acid, a cytotoxic sesquiterpene from the gum resin of Ferula asafoetida, blocks protein farnesyltransferase.
PubMed:
Herbal compound farnesiferol C exerts antiangiogenic and antitumor activity and targets multiple aspects of VEGFR1 (Flt1) or VEGFR2 (Flk1) signaling cascades.
PubMed:
A new sesquiterpenoid coumarin from Ferula assafoetida.
PubMed:
[Chemical constituents from roots of Ferula sinkiangensis].
PubMed:
Structure-based virtual screening for the discovery of natural inhibitors for human rhinovirus coat protein.
PubMed:
Sesquiterpene coumarins from Ferula szowitsiana and in vitro antileishmanial activity of 7-prenyloxycoumarins against promastigotes.