farnesiferol C

CAS: 512-17-4 C24 H30 O4 MW: 382.49990000

Identification

Namefarnesiferol C
CAS Number512-17-4
FDA UNII56P18T724F
Molecular FormulaC24 H30 O4
Molecular Weight382.49990000
Nikkaji NumberJ13.342F

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 0.02342 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for farnesiferol C usage levels up tonot for fragrance use.
Recommendation for farnesiferol C flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

ferula assa-foetida

Synonyms

7-[(E)-3- methyl-5-[(1R,3R,4S)-2,2,4-trimethyl-7-oxabicyclo[2.2.1]heptan-3-yl]pent-2-enoxy]chromen-2-one PubMed: The inhibitory effect of farnesiferol C against catalase; Kinetics, interaction mechanism and molecular docking simulation. PubMed: Farnesiferol C induces cell cycle arrest and apoptosis mediated by oxidative stress in MCF-7 cell line. PubMed: Biological activities of farnesiferol C: a review. PubMed: In Silico and In Vitro Evaluation of Cytotoxic Activities of Farnesiferol C and Microlobin on MCF-7, HeLa and KYSE Cell Lines. PubMed: Farnesiferol c induces apoptosis via regulation of L11 and c-Myc with combinational potential with anticancer drugs in non-small-cell lung cancers. PubMed: Modulation of Multidrug Resistance Protein 2 Efflux in the Cisplatin Resistance Human Ovarian Carcinoma Cells A2780/RCIS by Sesquiterpene Coumarins. PubMed: Anti-proliferative and Apoptotic Effects of Dendrosomal Farnesiferol C on Gastric Cancer Cells. PubMed: Reversal of P-glycoprotein-mediated multidrug resistance in MCF-7/Adr cancer cells by sesquiterpene coumarins. PubMed: Bioactive sesquiterpene coumarins from Ferula pseudalliacea. PubMed: Galbanic acid, a cytotoxic sesquiterpene from the gum resin of Ferula asafoetida, blocks protein farnesyltransferase. PubMed: Herbal compound farnesiferol C exerts antiangiogenic and antitumor activity and targets multiple aspects of VEGFR1 (Flt1) or VEGFR2 (Flk1) signaling cascades. PubMed: A new sesquiterpenoid coumarin from Ferula assafoetida. PubMed: [Chemical constituents from roots of Ferula sinkiangensis]. PubMed: Structure-based virtual screening for the discovery of natural inhibitors for human rhinovirus coat protein. PubMed: Sesquiterpene coumarins from Ferula szowitsiana and in vitro antileishmanial activity of 7-prenyloxycoumarins against promastigotes.