hydroxy-alpha-sanshool

(2E,6Z,8E,10E)-N-(2- hydroxy-2-methylpropyl)dodeca-2,6,8,10-tetraenamide PubMed: Anesthetic constituents of Zanthoxylum bungeanum Maxim.: A pharmacokinetic study. PubMed: Complementary and synergistic therapeutic effects of compounds found in Kampo medicine: analysis of daikenchuto. PubMed: Contraction of gut smooth muscle cells assessed by fluorescence imaging. PubMed: Hydroxy-α sanshool induces colonic motor activity in rat proximal colon: a possible involvement of KCNK9. PubMed: All-trans-configuration in Zanthoxylum alkylamides swaps the tingling with a numbing sensation and diminishes salivation. PubMed: Preventive Effect of TU-100 on a Type-2 Model of Colitis in Mice: Possible Involvement of Enhancing Adrenomedullin in Intestinal Epithelial Cells. PubMed: Characterization and comparison of the pungent components in commercial Zanthoxylum bungeanum oil and Zanthoxylum schinifolium oil. PubMed: A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain. PubMed: Population pharmacokinetic analysis of daikenchuto, a traditional Japanese medicine (Kampo) in Japanese and US health volunteers. PubMed: Inhibition by TRPA1 agonists of compound action potentials in the frog sciatic nerve. PubMed: Total synthesis of hydroxy-α- and hydroxy-β-sanshool using Suzuki-Miyaura coupling. PubMed: Daikenchuto (TU-100) ameliorates colon microvascular dysfunction via endogenous adrenomedullin in Crohn's disease rat model. PubMed: Pharmacokinetics of daikenchuto, a traditional Japanese medicine (kampo) after single oral administration to healthy Japanese volunteers. PubMed: A tingling sanshool derivative excites primary sensory neurons and elicits nocifensive behavior in rats. PubMed: Profiling of the compounds absorbed in human plasma and urine after oral administration of a traditional Japanese (kampo) medicine, daikenchuto. PubMed: Physiological basis of tingling paresthesia evoked by hydroxy-alpha-sanshool. PubMed: Molecular and cellular mechanisms of trigeminal chemosensation. PubMed: Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels. PubMed: Activation of lumbar spinal wide-dynamic range neurons by a sanshool derivative. PubMed: Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels. PubMed: Aroma constituents and alkylamides of red and green huajiao (Zanthoxylum bungeanum and Zanthoxylum schinifolium). PubMed: Hydroxy-alpha-sanshool activates TRPV1 and TRPA1 in sensory neurons. PubMed: Characterization of the pungent principles and the essential oil of Zanthoxylum schinifolium pericarp. PubMed: Quantitative analysis of sanshool compounds in Japanese pepper (Xanthoxylum piperitum DC.) and their pungent characteristics. PubMed: Pungent qualities of sanshool-related compounds evaluated by a sensory test and activation of rat TRPV1. PubMed: Alkylamides that produce tingling paresthesia activate tactile and thermal trigeminal neurons.