D-eritadenine
lentysine
Identification
| Name | D-eritadenine |
| CAS Number | 23918-98-1 |
| FDA UNII | 41T27K4B9F |
| Molecular Formula | C9 H11 N5 O4 |
| Molecular Weight | 253.21847000 |
| Nikkaji Number | J16.032F |
| XlogP3 | -1.80 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 2.406e+004 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for D-eritadenine usage levels up to | not for fragrance use. |
| Recommendation for D-eritadenine flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
D-4-(6-
amino-9H-purin-9-yl)-4-deoxyerythronic acid
(2R,3R)-4-(6-
aminopurin-9-yl)-2,3-dihydroxybutanoic acid
D-erythro-
eritadenine
erythronic acid, 4-(6-amino-9H-purin-9-yl)-4-deoxy-, D-
lentysine
9H-
purine-9-butanoic acid, 6-amino-alpha,beta-dihydroxy-, (R-(R*,R*))- (9CI)
PubMed:
Efficacy of S-adenosylhomocysteine hydrolase inhibitors, D-eritadenine and (S)-DHPA, against the growth of Cryptosporidium parvum in vitro.
PubMed:
Characterization of S-adenosylhomocysteine hydrolase from Cryptosporidium parvum.
PubMed:
Structure and function of eritadenine and its 3-deaza analogues: potent inhibitors of S-adenosylhomocysteine hydrolase and hypocholesterolemic agents.
PubMed:
Inhibition of S-adenosylhomocysteine hydrolase by acyclic sugar adenosine analogue D-eritadenine. Crystal structure of S-adenosylhomocysteine hydrolase complexed with D-eritadenine.
PubMed:
High recombinagenic activities of three antiviral agents, adenine derivatives, in the Drosophila wing spot test.
PubMed:
Inhibition of phosphatase by open-chain nucleoside analogues in insects.
PubMed:
Disposition of homocysteine in rat hepatocytes and in nontransformed and malignant mouse embryo fibroblasts following exposure to inhibitors of S-adenosylhomocysteine catabolism.
PubMed:
The synergism of nucleoside antibiotics combined with guanine 7-N-oxide against a rhabdovirus, infectious hematopoietic necrosis virus (IHNV).
PubMed:
The effect of aliphatic adenine analogues on S-adenosylhomocysteine and S-adenosylhomocysteine hydrolase in intact rat hepatocytes.