scutigeral
1-formyl-3-hydroxyneogrifolin
Identification
| Name | scutigeral |
| CAS Number | 65195-50-8 |
| FDA UNII | Search |
| Molecular Formula | C23 H32 O4 |
| Molecular Weight | 372.50484000 |
| MDL Number | MFCD02684418 |
| Nikkaji Number | J20.500A |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 0.0003818 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for scutigeral usage levels up to | not for fragrance use. |
| Recommendation for scutigeral flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
1-
formyl-3-hydroxyneogrifolin
2,3,4-
trihydroxy-6-methyl-5-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]benzaldehyde
PubMed:
Molecular cloning, functional characterization of the porcine transient receptor potential V1 (pTRPV1) and pharmacological comparison with endogenous pTRPV1.
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Capsaicin stimulates the non-store-operated Ca2+ entry but inhibits the store-operated Ca2+ entry in neutrophils.
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Activities of prenylphenol derivatives from fruitbodies of Albatrellus spp. on the human and rat vanilloid receptor 1 (VR1) and characterisation of the novel natural product, confluentin.
PubMed:
Pharmacology of vanilloids at recombinant and endogenous rat vanilloid receptors.
PubMed:
Characterisation using FLIPR of human vanilloid VR1 receptor pharmacology.
PubMed:
The cloned rat vanilloid receptor VR1 mediates both R-type binding and C-type calcium response in dorsal root ganglion neurons.
PubMed:
A non-pungent triprenyl phenol of fungal origin, scutigeral, stimulates rat dorsal root ganglion neurons via interaction at vanilloid receptors.