eupolauridine

canangine

CAS: 58786-39-3 C14 H8 N2 MW: 204.23176000

Identification

Nameeupolauridine
CAS Number58786-39-3
FDA UNIISearch
Molecular FormulaC14 H8 N2
Molecular Weight204.23176000
Nikkaji NumberJ13.838J

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 11.21 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for eupolauridine usage levels up tonot for fragrance use.
Recommendation for eupolauridine flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

cananga odorata bark

Synonyms

canangine indeno(1,2,3-ij)(2,7)naphthyridine PubMed: Two plant-derived aporphinoid alkaloids exert their antifungal activity by disrupting mitochondrial iron-sulfur cluster biosynthesis. PubMed: The synthesis and biological evaluation of alkyl and benzyl naphthyridinium analogs of eupolauridine as potential antimicrobial and cytotoxic agents. PubMed: Isolation and synthesis of antiproliferative eupolauridine alkaloids of Ambavia gerrardii from the Madagascar Dry Forest. PubMed: Antifungal activity of eupolauridine and its action on DNA topoisomerases. PubMed: [Polycyclic aromatic alkaloids. 9. Synthesis and antifungal activity of diazafluoroanthene alkaloids]. PubMed: Characterization of DNA topoisomerase I from Candida albicans as a target for drug discovery. PubMed: 3-Methoxysampangine, a novel antifungal copyrine alkaloid from Cleistopholis patens. PubMed: Anticandidal activity of eupolauridine and onychine, alkaloids from Cleistopholis patens. PubMed: Alkaloids of Annonaceae. XIV. Identification of canangine and eupolauridine, new alkaloids with a naphthyridine nucleus.