eupolauridine
canangine
Identification
| Name | eupolauridine |
| CAS Number | 58786-39-3 |
| FDA UNII | Search |
| Molecular Formula | C14 H8 N2 |
| Molecular Weight | 204.23176000 |
| Nikkaji Number | J13.838J |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 11.21 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for eupolauridine usage levels up to | not for fragrance use. |
| Recommendation for eupolauridine flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
canangine
indeno(1,2,3-ij)(2,7)naphthyridine
PubMed:
Two plant-derived aporphinoid alkaloids exert their antifungal activity by disrupting mitochondrial iron-sulfur cluster biosynthesis.
PubMed:
The synthesis and biological evaluation of alkyl and benzyl naphthyridinium analogs of eupolauridine as potential antimicrobial and cytotoxic agents.
PubMed:
Isolation and synthesis of antiproliferative eupolauridine alkaloids of Ambavia gerrardii from the Madagascar Dry Forest.
PubMed:
Antifungal activity of eupolauridine and its action on DNA topoisomerases.
PubMed:
[Polycyclic aromatic alkaloids. 9. Synthesis and antifungal activity of diazafluoroanthene alkaloids].
PubMed:
Characterization of DNA topoisomerase I from Candida albicans as a target for drug discovery.
PubMed:
3-Methoxysampangine, a novel antifungal copyrine alkaloid from Cleistopholis patens.
PubMed:
Anticandidal activity of eupolauridine and onychine, alkaloids from Cleistopholis patens.
PubMed:
Alkaloids of Annonaceae. XIV. Identification of canangine and eupolauridine, new alkaloids with a naphthyridine nucleus.