heptaphylline

3-formyl-2-hydroxy-1-prenylcarbazole

CAS: 17750-35-5 C18 H17 N O2 MW: 279.33889000

Identification

Nameheptaphylline
CAS Number17750-35-5
FDA UNIISearch
Molecular FormulaC18 H17 N O2
Molecular Weight279.33889000
Nikkaji NumberJ13.606I

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 0.03683 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for heptaphylline usage levels up tonot for fragrance use.
Recommendation for heptaphylline flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

clausena lansium leaf

Synonyms

3- formyl-2-hydroxy-1-prenyl carbazole 3- formyl-2-hydroxy-1-prenylcarbazole 2- hydroxy-1-(3-methylbut-2-enyl)-9H-carbazole-3-carbaldehyde PubMed: A new coruleoellagic acid derivative from stems of Rhodamnia dumetorum. PubMed: Carbazole-pyranocoumarin conjugate and two carbazole alkaloids from the stems of Clausena excavata. PubMed: Synthesis of Carbazole Alkaloids by Ring-Closing Metathesis and Ring Rearrangement-Aromatization. PubMed: Heptaphylline induces apoptosis in human colon adenocarcinoma cells through bid and Akt/NF-κB (p65) pathways. PubMed: [Synthetic studies on natural products with aromatic nitrogen heterocycles based on development of the methods for the formation of aryl carbon-nitrogen bond]. PubMed: Synthesis of substituted indoline and carbazole by benzyne-mediated cyclization-functionalization. PubMed: Synthesis and cytotoxic activity of the heptaphylline and 7-methoxyheptaphylline series. PubMed: Claurailas A-D, cytotoxic carbazole alkaloids from the roots of Clausena harmandiana. PubMed: Inhibitory effect of oxycoumarins isolated from the Thai medicinal plant Clausena guillauminii on the inflammation mediators, iNOS, TNF-alpha, and COX-2 expression in mouse macrophage RAW 264.7. PubMed: Coumarins and carbazoles with antiplasmodial activity from Clausena harmandiana. PubMed: Synthesis of heptaphylline.