heptaphylline
3-formyl-2-hydroxy-1-prenylcarbazole
Identification
| Name | heptaphylline |
| CAS Number | 17750-35-5 |
| FDA UNII | Search |
| Molecular Formula | C18 H17 N O2 |
| Molecular Weight | 279.33889000 |
| Nikkaji Number | J13.606I |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 0.03683 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for heptaphylline usage levels up to | not for fragrance use. |
| Recommendation for heptaphylline flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
3-
formyl-2-hydroxy-1-prenyl carbazole
3-
formyl-2-hydroxy-1-prenylcarbazole
2-
hydroxy-1-(3-methylbut-2-enyl)-9H-carbazole-3-carbaldehyde
PubMed:
A new coruleoellagic acid derivative from stems of Rhodamnia dumetorum.
PubMed:
Carbazole-pyranocoumarin conjugate and two carbazole alkaloids from the stems of Clausena excavata.
PubMed:
Synthesis of Carbazole Alkaloids by Ring-Closing Metathesis and Ring Rearrangement-Aromatization.
PubMed:
Heptaphylline induces apoptosis in human colon adenocarcinoma cells through bid and Akt/NF-κB (p65) pathways.
PubMed:
[Synthetic studies on natural products with aromatic nitrogen heterocycles based on development of the methods for the formation of aryl carbon-nitrogen bond].
PubMed:
Synthesis of substituted indoline and carbazole by benzyne-mediated cyclization-functionalization.
PubMed:
Synthesis and cytotoxic activity of the heptaphylline and 7-methoxyheptaphylline series.
PubMed:
Claurailas A-D, cytotoxic carbazole alkaloids from the roots of Clausena harmandiana.
PubMed:
Inhibitory effect of oxycoumarins isolated from the Thai medicinal plant Clausena guillauminii on the inflammation mediators, iNOS, TNF-alpha, and COX-2 expression in mouse macrophage RAW 264.7.
PubMed:
Coumarins and carbazoles with antiplasmodial activity from Clausena harmandiana.
PubMed:
Synthesis of heptaphylline.