girinimbine
Identification
| Name | girinimbine |
| CAS Number | 23095-44-5 |
| FDA UNII | Search |
| Molecular Formula | C18 H17 N O |
| Molecular Weight | 263.33969000 |
| Nikkaji Number | J16.770C |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 0.03098 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for girinimbine usage levels up to | not for fragrance use. |
| Recommendation for girinimbine flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
pyrano(3,2-a)carbazole, 3,11-dihydro-3,3,5-trimethyl-
3,3,5-
trimethyl-11H-pyrano[3,2-a]carbazole
PubMed:
Anticancer and anti-inflammatory activities of girinimbine isolated from
Murraya koenigii
PubMed:
Four new carbazole alkaloids from Murraya koenigii that display anti-inflammatory and anti-microbial activities.
PubMed:
In vitro and in vivo anti-angiogenic activity of girinimbine isolated from Murraya koenigii.
PubMed:
Efficient construction of pyrano[3,2-a]carbazoles: application to a biomimetic total synthesis of cyclized monoterpenoid pyrano[3,2-a]carbazole alkaloids.
PubMed:
Apoptosis Effect of Girinimbine Isolated from Murraya koenigii on Lung Cancer Cells In Vitro.
PubMed:
Chemical constituents from stem bark and roots of Clausena anisata.
PubMed:
Anti-tumour promoting activity and antioxidant properties of girinimbine isolated from the stem bark of Murraya koenigii S.
PubMed:
A new carbazole alkaloid from the leaves of Malayan Murraya koenigii.
PubMed:
The growth suppressing effects of girinimbine on HepG2 involve induction of apoptosis and cell cycle arrest.
PubMed:
Efficient iron-mediated approach to pyrano[3,2-a]carbazole alkaloids--first total syntheses of O-methylmurrayamine A and 7-methoxymurrayacine, first asymmetric synthesis and assignment of the absolute configuration of (-)-trans-dihydroxygirinimbine.
PubMed:
Murrayakoeninol--a new carbazole alkaloid from Murraya koenigii (Linn) Spreng.
PubMed:
Anti-trichomonal, biochemical and toxicological activities of methanolic extract and some carbazole alkaloids isolated from the leaves of Murraya koenigii growing in Nigeria.
PubMed:
[Study on carbazole alkaloids of Murraya microphylla].
PubMed:
Carbazole alkaloids as new cell cycle inhibitor and apoptosis inducers from Clausena dunniana Levl.
PubMed:
Inhibition of cyclooxygenase activity and increase in platelet cyclic AMP by girinimbine, isolated from Murraya euchrestifolia.
PubMed:
Antimicrobial activity of carbazole derivatives.
PubMed:
Synthesis of girinimbine and (plus or minus) mahanimbine.
PubMed:
On the structures of girinimbine, mahanimbine, isomahanimbine, koenimbidine and murrayacine.