CAS: 1862-41-5 C17 H15 N O2 MW: 265.31195000

Identification

Nameanonaine
CAS Number1862-41-5
FDA UNIISearch
Molecular FormulaC17 H15 N O2
Molecular Weight265.31195000
Nikkaji NumberJ14.381B

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 13.13 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for anonaine usage levels up tonot for fragrance use.
Recommendation for anonaine flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

annona cherimolia root nelumbo nucifera sugar-apple seed

Synonyms

5H- benzo(g)-1,3-benzodioxolo(6,5,4-de)quinoline, 6,7,7a,8-tetrahydro-, (R)- PubMed: Molecular docking studies of bioactive compounds from Annona muricata Linn as potential inhibitors for Bcl-2, Bcl-w and Mcl-1 antiapoptotic proteins. PubMed: Acetogenins and alkaloids during the initial development of Annona muricata L. (Annonaceae). PubMed: Cytotoxicity and bacterial membrane destabilization induced by Annona squamosa L. extracts. PubMed: Revealing the potency of Annona muricata leaves extract as FOXO1 inhibitor for diabetes mellitus treatment through computational study. PubMed: Alkaloids from aerial parts of Annona senegalensis against Streptococcus mutans. PubMed: Cytotoxic Alkaloids from the Stem of Xylopia laevigata. PubMed: DNA topoisomerase-directed anticancerous alkaloids: ADMET-based screening, molecular docking, and dynamics simulation. PubMed: Antioxidant and anticancer aporphine alkaloids from the leaves of Nelumbo nucifera Gaertn. cv. Rosa-plena. PubMed: Antioxidant and anticancer constituents from the leaves of Liriodendron tulipifera. PubMed: Anthelmintic activities of aporphine from Nelumbo nucifera Gaertn. cv. Rosa-plena against Hymenolepis nana. PubMed: Phytochemical study of the alkaloidal fractions of Unonopsis duckei R. E. Fr. guided by electrospray ionisation ion-trap tandem mass spectrometry. PubMed: Anti cancer activity on Graviola, an exciting medicinal plant extract vs various cancer cell lines and a detailed computational study on its potent anti-cancerous leads. PubMed: The pharmacological activities of (-)-anonaine. PubMed: Pyridocoumarin, aristolactam and aporphine alkaloids from the Australian rainforest plant Goniothalamus australis. PubMed: Antioxidant and antimicrobial activities of aporphinoids and other alkaloids from the bark of Annona salzmannii A. DC. (Annonaceae). PubMed: Antidepressant-like effects of an alkaloid extract of the aerial parts of Annona cherimolia in mice. PubMed: Bioactive constituents from Michelia champaca. PubMed: (-)-Anonaine induces DNA damage and inhibits growth and migration of human lung carcinoma h1299 cells. PubMed: The trypanocidal activity of the alkaloid oliverine involves inhibition of DNA synthesis. PubMed: Antiplasmodial activity of aporphine alkaloids and sesquiterpene lactones from Liriodendron tulipifera L. PubMed: Alkaloids from Fissistigma latifolium (Dunal) Merr. PubMed: Preparative separation of isoquinoline alkaloids from Stephania yunnanensis by pH-zone-refining counter-current chromatography. PubMed: Alkaloids from the bark of Guatteria hispida and their evaluation as antioxidant and antimicrobial agents. PubMed: Cytotoxic and antiviral activities of aporphine alkaloids of Magnolia grandiflora L. PubMed: Antimicrobial evaluation of clerodane diterpenes from Polyalthia longifolia var. pendula. PubMed: (-)-Anonaine induces apoptosis through Bax- and caspase-dependent pathways in human cervical cancer (HeLa) cells. PubMed: Effects of anonaine on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells. PubMed: Antioxidant and cytotoxic activities of canadine: biological effects and structural aspects. PubMed: Vascular activity of (-)-anonaine, (-)-roemerine and (-)-pukateine, three natural 6a(R)-1,2-methylenedioxyaporphines with different affinities for alpha1-adrenoceptor subtypes. PubMed: Tetrahydroprotoberberine and aporphine alkaloids from rollinia leptopetala. PubMed: Effects of various isoquinoline alkaloids on in vitro 3H-dopamine uptake by rat striatal synaptosomes. PubMed: Relaxant activity of three aporphine alkaloids from Annona cherimolia on isolated aorta of rat. PubMed: Iron-reducing and free-radical-scavenging properties of apomorphine and some related benzylisoquinolines. PubMed: Antioxidant action of benzylisoquinoline alkaloids. PubMed: Antimicrobial activity of benzylisoquinoline alkaloids from Annona salzmanii D.C. PubMed: Inhibition of nonenzymic lipid peroxidation by benzylisoquinoline alkaloids. PubMed: [Studies on the chemical constituents of Annona squamosa]. PubMed: [Norstephalagine and atherospermidine: two smooth muscle relaxant aporphines from Artabotrys maingayi]. PubMed: Screening of isoquinoline alkaloids and their derivatives for antibacterial and antifungal activities. PubMed: Antimicrobial activity of benzylisoquinoline alkaloids. PubMed: Alkaloids from Chasmanthera dependens. PubMed: Alkaloids of Nelumbo lutea (Wild.) pers. (Nymphaeaceae) PubMed: Phenol oxidation and biosynthesis. XV. The biosynthesis of roemerine, anonaine, and mecambrine.