anonaine
Identification
| Name | anonaine |
| CAS Number | 1862-41-5 |
| FDA UNII | Search |
| Molecular Formula | C17 H15 N O2 |
| Molecular Weight | 265.31195000 |
| Nikkaji Number | J14.381B |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 13.13 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for anonaine usage levels up to | not for fragrance use. |
| Recommendation for anonaine flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
5H-
benzo(g)-1,3-benzodioxolo(6,5,4-de)quinoline, 6,7,7a,8-tetrahydro-, (R)-
PubMed:
Molecular docking studies of bioactive compounds from Annona muricata Linn as potential inhibitors for Bcl-2, Bcl-w and Mcl-1 antiapoptotic proteins.
PubMed:
Acetogenins and alkaloids during the initial development of Annona muricata L. (Annonaceae).
PubMed:
Cytotoxicity and bacterial membrane destabilization induced by Annona squamosa L. extracts.
PubMed:
Revealing the potency of Annona muricata leaves extract as FOXO1 inhibitor for diabetes mellitus treatment through computational study.
PubMed:
Alkaloids from aerial parts of Annona senegalensis against Streptococcus mutans.
PubMed:
Cytotoxic Alkaloids from the Stem of Xylopia laevigata.
PubMed:
DNA topoisomerase-directed anticancerous alkaloids: ADMET-based screening, molecular docking, and dynamics simulation.
PubMed:
Antioxidant and anticancer aporphine alkaloids from the leaves of Nelumbo nucifera Gaertn. cv. Rosa-plena.
PubMed:
Antioxidant and anticancer constituents from the leaves of Liriodendron tulipifera.
PubMed:
Anthelmintic activities of aporphine from Nelumbo nucifera Gaertn. cv. Rosa-plena against Hymenolepis nana.
PubMed:
Phytochemical study of the alkaloidal fractions of Unonopsis duckei R. E. Fr. guided by electrospray ionisation ion-trap tandem mass spectrometry.
PubMed:
Anti cancer activity on Graviola, an exciting medicinal plant extract vs various cancer cell lines and a detailed computational study on its potent anti-cancerous leads.
PubMed:
The pharmacological activities of (-)-anonaine.
PubMed:
Pyridocoumarin, aristolactam and aporphine alkaloids from the Australian rainforest plant Goniothalamus australis.
PubMed:
Antioxidant and antimicrobial activities of aporphinoids and other alkaloids from the bark of Annona salzmannii A. DC. (Annonaceae).
PubMed:
Antidepressant-like effects of an alkaloid extract of the aerial parts of Annona cherimolia in mice.
PubMed:
Bioactive constituents from Michelia champaca.
PubMed:
(-)-Anonaine induces DNA damage and inhibits growth and migration of human lung carcinoma h1299 cells.
PubMed:
The trypanocidal activity of the alkaloid oliverine involves inhibition of DNA synthesis.
PubMed:
Antiplasmodial activity of aporphine alkaloids and sesquiterpene lactones from Liriodendron tulipifera L.
PubMed:
Alkaloids from Fissistigma latifolium (Dunal) Merr.
PubMed:
Preparative separation of isoquinoline alkaloids from Stephania yunnanensis by pH-zone-refining counter-current chromatography.
PubMed:
Alkaloids from the bark of Guatteria hispida and their evaluation as antioxidant and antimicrobial agents.
PubMed:
Cytotoxic and antiviral activities of aporphine alkaloids of Magnolia grandiflora L.
PubMed:
Antimicrobial evaluation of clerodane diterpenes from Polyalthia longifolia var. pendula.
PubMed:
(-)-Anonaine induces apoptosis through Bax- and caspase-dependent pathways in human cervical cancer (HeLa) cells.
PubMed:
Effects of anonaine on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells.
PubMed:
Antioxidant and cytotoxic activities of canadine: biological effects and structural aspects.
PubMed:
Vascular activity of (-)-anonaine, (-)-roemerine and (-)-pukateine, three natural 6a(R)-1,2-methylenedioxyaporphines with different affinities for alpha1-adrenoceptor subtypes.
PubMed:
Tetrahydroprotoberberine and aporphine alkaloids from rollinia leptopetala.
PubMed:
Effects of various isoquinoline alkaloids on in vitro 3H-dopamine uptake by rat striatal synaptosomes.
PubMed:
Relaxant activity of three aporphine alkaloids from Annona cherimolia on isolated aorta of rat.
PubMed:
Iron-reducing and free-radical-scavenging properties of apomorphine and some related benzylisoquinolines.
PubMed:
Antioxidant action of benzylisoquinoline alkaloids.
PubMed:
Antimicrobial activity of benzylisoquinoline alkaloids from Annona salzmanii D.C.
PubMed:
Inhibition of nonenzymic lipid peroxidation by benzylisoquinoline alkaloids.
PubMed:
[Studies on the chemical constituents of Annona squamosa].
PubMed:
[Norstephalagine and atherospermidine: two smooth muscle relaxant aporphines from Artabotrys maingayi].
PubMed:
Screening of isoquinoline alkaloids and their derivatives for antibacterial and antifungal activities.
PubMed:
Antimicrobial activity of benzylisoquinoline alkaloids.
PubMed:
Alkaloids from Chasmanthera dependens.
PubMed:
Alkaloids of Nelumbo lutea (Wild.) pers. (Nymphaeaceae)
PubMed:
Phenol oxidation and biosynthesis. XV. The biosynthesis of roemerine, anonaine, and mecambrine.