asimilobine
Identification
| Name | asimilobine |
| CAS Number | 6871-21-2 |
| FDA UNII | Search |
| Molecular Formula | C17 H17 N O2 |
| Molecular Weight | 267.32789000 |
| Nikkaji Number | J15.061D |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 52.39 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for asimilobine usage levels up to | not for fragrance use. |
| Recommendation for asimilobine flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
(6aR)-1-
methoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2-ol
PubMed:
Acetogenins and alkaloids during the initial development of Annona muricata L. (Annonaceae).
PubMed:
[Studies on alkaloids from Fissistigma oldhamii].
PubMed:
Cytotoxicity and bacterial membrane destabilization induced by Annona squamosa L. extracts.
PubMed:
Alkaloids from aerial parts of Annona senegalensis against Streptococcus mutans.
PubMed:
Chemical profiling of the tuber of Stephania cambodica Gagnep. (Menispermaceae) and analytical control by UHPLC-DAD.
PubMed:
Chronic consumption of Annona muricata juice triggers and aggravates cerebral tau phosphorylation in wild-type and MAPT transgenic mice.
PubMed:
Quantitative Determination of Alkaloids in Lotus Flower (Flower Buds of Nelumbo nucifera) and Their Melanogenesis Inhibitory Activity.
PubMed:
Cytotoxic Alkaloids from the Stem of Xylopia laevigata.
PubMed:
In vitro opioid receptor affinity and in vivo behavioral studies of Nelumbo nucifera flower.
PubMed:
Direct infusion ESI-IT-MSn alkaloid profile and isolation of tetrahydroharman and other alkaloids from Bocageopsis pleiosperma maas (Annonaceae).
PubMed:
Human Ether-Ã -go-go Related Gene (hERG) Channel Blocking Aporphine Alkaloids from Lotus Leaves and Their Quantitative Analysis in Dietary Weight Loss Supplements.
PubMed:
Active ingredients from natural botanicals in the treatment of obesity.
PubMed:
Antioxidant and anticancer aporphine alkaloids from the leaves of Nelumbo nucifera Gaertn. cv. Rosa-plena.
PubMed:
Antimicrobial glycoalkaloids from the tubers of Stephania succifera.
PubMed:
[Cytotoxic alkaloids from stems of Nelumbo nucifera].
PubMed:
Anthelmintic activities of aporphine from Nelumbo nucifera Gaertn. cv. Rosa-plena against Hymenolepis nana.
PubMed:
Phytochemical study of the alkaloidal fractions of Unonopsis duckei R. E. Fr. guided by electrospray ionisation ion-trap tandem mass spectrometry.
PubMed:
Anti cancer activity on Graviola, an exciting medicinal plant extract vs various cancer cell lines and a detailed computational study on its potent anti-cancerous leads.
PubMed:
Studies on the alkaloids of the bark of Magnolia officinalis: isolation and on-line analysis by HPLC-ESI-MS(n).
PubMed:
Pyridocoumarin, aristolactam and aporphine alkaloids from the Australian rainforest plant Goniothalamus australis.
PubMed:
Antioxidant and antimicrobial activities of aporphinoids and other alkaloids from the bark of Annona salzmannii A. DC. (Annonaceae).
PubMed:
Anti-acetylcholinesterase, anti-α-glucosidase, anti-leishmanial and anti-fungal activities of chemical constituents of Beilschmiedia species.
PubMed:
Bioactive constituents from Michelia champaca.
PubMed:
Antiplasmodial activity of aporphine alkaloids and sesquiterpene lactones from Liriodendron tulipifera L.
PubMed:
Alkaloids from Fissistigma latifolium (Dunal) Merr.
PubMed:
Antimicrobial evaluation of clerodane diterpenes from Polyalthia longifolia var. pendula.
PubMed:
[Five alkaloids from vine stems of Diploclisia affinis].
PubMed:
Effects of asimilobine on dopamine biosynthesis and l-DOPA-induced cytotoxicity in PC12 cells.
PubMed:
Taspine: bioactivity-guided isolation and molecular ligand-target insight of a potent acetylcholinesterase inhibitor from Magnolia x soulangiana.
PubMed:
Isoquinoline derivatives isolated from the fruit of Annona muricata as 5-HTergic 5-HT1A receptor agonists in rats: unexploited antidepressive (lead) products.
PubMed:
Screening of medicinal plants from Suriname for 5-HT(1A) ligands: Bioactive isoquinoline alkaloids from the fruit of Annona muricata.
PubMed:
Cytotoxic and antimalarial alkaloids from the tubers of Stephania pierrei.
PubMed:
Asimilobine and lirinidine, serotonergic receptor antagonists, from Nelumbo nucifera.
PubMed:
[Anaxagoreine, a new aporphine alkaloide, isolated from two species of the genus Anaxagorea].
PubMed:
[Studies on the ingredients of aristolochiaceous plants. Isolation of asimilobine from crude drug "Batore"].