asimilobine

CAS: 6871-21-2 C17 H17 N O2 MW: 267.32789000

Identification

Nameasimilobine
CAS Number6871-21-2
FDA UNIISearch
Molecular FormulaC17 H17 N O2
Molecular Weight267.32789000
Nikkaji NumberJ15.061D

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 52.39 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for asimilobine usage levels up tonot for fragrance use.
Recommendation for asimilobine flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

annona cherimola

Synonyms

(6aR)-1- methoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2-ol PubMed: Acetogenins and alkaloids during the initial development of Annona muricata L. (Annonaceae). PubMed: [Studies on alkaloids from Fissistigma oldhamii]. PubMed: Cytotoxicity and bacterial membrane destabilization induced by Annona squamosa L. extracts. PubMed: Alkaloids from aerial parts of Annona senegalensis against Streptococcus mutans. PubMed: Chemical profiling of the tuber of Stephania cambodica Gagnep. (Menispermaceae) and analytical control by UHPLC-DAD. PubMed: Chronic consumption of Annona muricata juice triggers and aggravates cerebral tau phosphorylation in wild-type and MAPT transgenic mice. PubMed: Quantitative Determination of Alkaloids in Lotus Flower (Flower Buds of Nelumbo nucifera) and Their Melanogenesis Inhibitory Activity. PubMed: Cytotoxic Alkaloids from the Stem of Xylopia laevigata. PubMed: In vitro opioid receptor affinity and in vivo behavioral studies of Nelumbo nucifera flower. PubMed: Direct infusion ESI-IT-MSn alkaloid profile and isolation of tetrahydroharman and other alkaloids from Bocageopsis pleiosperma maas (Annonaceae). PubMed: Human Ether-à-go-go Related Gene (hERG) Channel Blocking Aporphine Alkaloids from Lotus Leaves and Their Quantitative Analysis in Dietary Weight Loss Supplements. PubMed: Active ingredients from natural botanicals in the treatment of obesity. PubMed: Antioxidant and anticancer aporphine alkaloids from the leaves of Nelumbo nucifera Gaertn. cv. Rosa-plena. PubMed: Antimicrobial glycoalkaloids from the tubers of Stephania succifera. PubMed: [Cytotoxic alkaloids from stems of Nelumbo nucifera]. PubMed: Anthelmintic activities of aporphine from Nelumbo nucifera Gaertn. cv. Rosa-plena against Hymenolepis nana. PubMed: Phytochemical study of the alkaloidal fractions of Unonopsis duckei R. E. Fr. guided by electrospray ionisation ion-trap tandem mass spectrometry. PubMed: Anti cancer activity on Graviola, an exciting medicinal plant extract vs various cancer cell lines and a detailed computational study on its potent anti-cancerous leads. PubMed: Studies on the alkaloids of the bark of Magnolia officinalis: isolation and on-line analysis by HPLC-ESI-MS(n). PubMed: Pyridocoumarin, aristolactam and aporphine alkaloids from the Australian rainforest plant Goniothalamus australis. PubMed: Antioxidant and antimicrobial activities of aporphinoids and other alkaloids from the bark of Annona salzmannii A. DC. (Annonaceae). PubMed: Anti-acetylcholinesterase, anti-α-glucosidase, anti-leishmanial and anti-fungal activities of chemical constituents of Beilschmiedia species. PubMed: Bioactive constituents from Michelia champaca. PubMed: Antiplasmodial activity of aporphine alkaloids and sesquiterpene lactones from Liriodendron tulipifera L. PubMed: Alkaloids from Fissistigma latifolium (Dunal) Merr. PubMed: Antimicrobial evaluation of clerodane diterpenes from Polyalthia longifolia var. pendula. PubMed: [Five alkaloids from vine stems of Diploclisia affinis]. PubMed: Effects of asimilobine on dopamine biosynthesis and l-DOPA-induced cytotoxicity in PC12 cells. PubMed: Taspine: bioactivity-guided isolation and molecular ligand-target insight of a potent acetylcholinesterase inhibitor from Magnolia x soulangiana. PubMed: Isoquinoline derivatives isolated from the fruit of Annona muricata as 5-HTergic 5-HT1A receptor agonists in rats: unexploited antidepressive (lead) products. PubMed: Screening of medicinal plants from Suriname for 5-HT(1A) ligands: Bioactive isoquinoline alkaloids from the fruit of Annona muricata. PubMed: Cytotoxic and antimalarial alkaloids from the tubers of Stephania pierrei. PubMed: Asimilobine and lirinidine, serotonergic receptor antagonists, from Nelumbo nucifera. PubMed: [Anaxagoreine, a new aporphine alkaloide, isolated from two species of the genus Anaxagorea]. PubMed: [Studies on the ingredients of aristolochiaceous plants. Isolation of asimilobine from crude drug "Batore"].