2-farnesyl-5-methylresorcinol

CAS: 6903-07-7 C22 H32 O2 MW: 328.49544000

Identification

Namegrifolin
CAS Number6903-07-7
FDA UNIISearch
Molecular FormulaC22 H32 O2
Molecular Weight328.49544000
Nikkaji NumberJ14.586F

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 0.001658 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for grifolin usage levels up tonot for fragrance use.
Recommendation for grifolin flavor usage levels up tonot for flavor use.

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

Potential Uses

None Found

Natural Occurrence

grifola confluens PMC

Synonyms

2- farnesyl-5-methylresorcinol 5- methyl-2-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]benzene-1,3-diol PubMed: Grifolin Attenuates White Matter Lesion in Oxygen/Glucose Deprivation. PubMed: Grifolin induces apoptosis and promotes cell cycle arrest in the A2780 human ovarian cancer cell line via inactivation of the ERK1/2 and Akt pathways. PubMed: Grifolin exhibits anti-cancer activity by inhibiting the development and invasion of gastric tumor cells. PubMed: Grifolin derivatives from Albatrellus ovinus as TRPV1 receptor blockers for cosmetic applications. PubMed: Total Synthesis of Grifolin, Grifolic Acid, LL-Z1272α, LL-Z1272β, and Ilicicolinic Acid A. PubMed: Grifolin inhibits tumor cells adhesion and migration via suppressing interplay between PGC1α and Fra-1 / LSF- MMP2 / CD44 axes. PubMed: Grifolin induces autophagic cell death by inhibiting the Akt/mTOR/S6K pathway in human ovarian cancer cells. PubMed: Grifolin directly targets ERK1/2 to epigenetically suppress cancer cell metastasis. PubMed: The role of targeting kinase activity by natural products in cancer chemoprevention and chemotherapy (Review). PubMed: Nine new farnesylphenols from the basidiomycete albatrellus caeruleoporus. PubMed: A review on antifungal activity of mushroom (basidiomycetes) extracts and isolated compounds. PubMed: Meroterpenoid pigments from the basidiomycete Albatrellus ovinus. PubMed: DAPK1 mediates the G1 phase arrest in human nasopharyngeal carcinoma cells induced by grifolin, a potential antitumor natural product. PubMed: Grifolin, a potent antitumour natural product upregulates death-associated protein kinase 1 DAPK1 via p53 in nasopharyngeal carcinoma cells. PubMed: Cyathane diterpenoids and nitrogenous terphenyl derivative from the fruiting bodies of basidiomycete Phellodon niger. PubMed: Cytotoxic grifolin derivatives isolated from the wild mushroom Boletus pseudocalopus (Basidiomycetes). PubMed: Antibacterial compounds from mushrooms I: a lanostane-type triterpene and prenylphenol derivatives from Jahnoporus hirtus and Albatrellus flettii and their activities against Bacillus cereus and Enterococcus faecalis. PubMed: Novel selective ligands for free fatty acid receptors GPR120 and GPR40. PubMed: A new meroterpenoid pigment from the basidiomycete Albatrellus confluens. PubMed: Grifolin, a potential antitumor natural product from the mushroom Albatrellus confluens, induces cell-cycle arrest in G1 phase via the ERK1/2 pathway. PubMed: Grifolin induces apoptosis via inhibition of PI3K/AKT signalling pathway in human osteosarcoma cells. PubMed: Screening of novel nuclear receptor agonists by a convenient reporter gene assay system using green fluorescent protein derivatives. PubMed: Grifolin derivatives from Albatrellus caeruleoporus, new inhibitors of nitric oxide production in RAW 264.7 cells. PubMed: Grifolin, a potential antitumor natural product from the mushroom Albatrellus confluens, inhibits tumor cell growth by inducing apoptosis in vitro. PubMed: Activity in vitro and in vivo against plant pathogenic fungi of grifolin isolated from the basidiomycete Albatrellus dispansus. PubMed: Use of a modified microplate bioassay method to investigate antibacterial activity in the Peruvian medicinal plant Peperomia galioides. PubMed: Structures and histamine release inhibitory effects of prenylated orcinol derivatives from Rhododendron dauricum. PubMed: Activities of prenylphenol derivatives from fruitbodies of Albatrellus spp. on the human and rat vanilloid receptor 1 (VR1) and characterisation of the novel natural product, confluentin. PubMed: Neogrifolin derivatives possessing anti-oxidative activity from the mushroom Albatrellus ovinus. PubMed: Antitumor beta glucan from the cultured fruit body of Agaricus blazei. PubMed: In vitro and in vivo leishmanicidal studies of Peperomia galioides (Piperaceae). PubMed: Piperogalin, a new prenylated diphenol from Peperomia galioides. PubMed: Hypocholesterolemic Action of Dietary Grifolin on Rats Fed with a High-cholesterol Diet. PubMed: Isolation of plasma cholesterol-lowering components from ningyotake (Polyporus confluens) mushroom. PubMed: A total synthesis of grifolin. PubMed: Synthesis of grifolin, an antibiotic from a Basidiomycete. PubMed: The structure of grifolin, an antibiotic from a basidiomycete. PubMed: Grifolin, an antibiotic from a basidiomycete.