casuarinin
Identification
| Name | casuarinin |
| CAS Number | 79786-01-9 |
| FDA UNII | Search |
| Molecular Formula | C41 H28 O26 |
| Molecular Weight | 936.65336000 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 1.067 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for casuarinin usage levels up to | not for fragrance use. |
| Recommendation for casuarinin flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
neo
vescalin, 11-de(6-carboxy-2,3,4-trihydroxyphenyl)-, cyclic 16,18-(4,4',5,5',6,6'-hexahydroxy(1,1-biphenyl)-2,2'-dicarboxylate) 17-(3,4,5-trihydroxybenzoate), (15beta)-
PubMed:
Variability in Foliar Ellagitannins of Hippophaë rhamnoides L. and Identification of a New Ellagitannin, Hippophaenin C.
PubMed:
Protective effect of casuarinin against glutamate-induced apoptosis in HT22 cells through inhibition of oxidative stress-mediated MAPK phosphorylation.
PubMed:
Impact of extraction techniques on antioxidant capacities and phytochemical composition of polyphenol-rich extracts.
PubMed:
Differences in Metabolism of Ellagitannins by Human Gut Microbiota ex Vivo Cultures.
PubMed:
Flavonoids, gallotannins and ellagitannins in Syzygium guineense and the traditional use among Malian healers.
PubMed:
Hepatoprotective and antioxidant effect of ellagitannins and galloyl esters isolated from Melaleuca styphelioides on carbon tetrachloride-induced hepatotoxicity in HepG2 cells.
PubMed:
High-resolution bioactivity profiling combined with HPLC-HRMS-SPE-NMR: α-Glucosidase inhibitors and acetylated ellagic acid rhamnosides from Myrcia palustris DC. (Myrtaceae).
PubMed:
Determination of phenolic compounds and antioxidant activity in leaves from wild Rubus L. species.
PubMed:
Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus acutissima Cortex.
PubMed:
Extracts and compounds with anti-diabetic complications and anti-cancer activity from Castanea mollissina Blume (Chinese chestnut).
PubMed:
Hepatitis C virus inhibitory hydrolysable tannins from the fruits of Terminalia chebula.
PubMed:
Chemical constituents from Melastoma dodecandrum and their inhibitory activity on interleukin-8 production in HT-29 cells.
PubMed:
Anti-Candida targets and cytotoxicity of casuarinin isolated from Plinia cauliflora leaves in a bioactivity-guided study.
PubMed:
C-glucosidic ellagitannins from Lythri herba (European Pharmacopoeia): chromatographic profile and structure determination.
PubMed:
Inhibitory effect of tannins from galls of Carpinus tschonoskii on the degranulation of RBL-2H3 Cells.
PubMed:
Casuarinin suppresses TARC/CCL17 and MDC/CCL22 production via blockade of NF-κB and STAT1 activation in HaCaT cells.
PubMed:
Casuarinin suppresses TNF-α-induced ICAM-1 expression via blockade of NF-κB activation in HaCaT cells.
PubMed:
Fatty acid synthase inhibitors from Geum japonicum Thunb. var. chinense.
PubMed:
Active compounds from Lagerstroemia speciosa, insulin-like glucose uptake-stimulatory/inhibitory and adipocyte differentiation-inhibitory activities in 3T3-L1 cells.
PubMed:
Anticancer and antioxidant tannins from Pimenta dioica leaves.
PubMed:
Casuarinin from the bark of Terminalia arjuna induces apoptosis and cell cycle arrest in human breast adenocarcinoma MCF-7 cells.
PubMed:
Induction of cell cycle arrest and apoptosis in human non-small cell lung cancer A549 cells by casuarinin from the bark of Terminalia arjuna Linn.
PubMed:
Casuarinin protects cultured MDCK cells from hydrogen peroxide-induced oxidative stress and DNA oxidative damage.
PubMed:
Determination of hydrolyzable tannins in the fruit of Terminalia chebula Retz. by high-performance liquid chromatography and capillary electrophoresis.
PubMed:
Antiherpes simplex virus type 2 activity of casuarinin from the bark of Terminalia arjuna Linn.
PubMed:
Identification of hydrolysable tannins in the reaction zone of Eucalyptus nitens wood by high performance liquid chromatography--electrospray ionisation mass spectrometry.
PubMed:
Induction of apoptosis by hydrolyzable tannins from Eugenia jambos L. on human leukemia cells.
PubMed:
Suppression of lipopolysaccharide-induced nuclear factor-kappaB activity by theaflavin-3,3'-digallate from black tea and other polyphenols through down-regulation of IkappaB kinase activity in macrophages.
PubMed:
Inhibitory effects of hydrolyzable tannins from Melastoma dodecandrum Lour. on nitric oxide production by a murine macrophage-like cell line, RAW264.7, activated with lipopolysaccharide and interferon-gamma.
PubMed:
Carbonic anhydrase inhibitors from the pericarps of Punica granatum L.
PubMed:
Antitumor agents, 129. Tannins and related compounds as selective cytotoxic agents.
PubMed:
In vitro screening of antimotility effect on human sperm with polyphenolic compounds purified from Chinese herbal medicines.
PubMed:
Tannins occurring in the toxic Brazilian plant Thiloa glaucocarpa.