casuarinin

CAS: 79786-01-9 C41 H28 O26 MW: 936.65336000

Identification

Namecasuarinin
CAS Number79786-01-9
FDA UNIISearch
Molecular FormulaC41 H28 O26
Molecular Weight936.65336000

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 1.067 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for casuarinin usage levels up tonot for fragrance use.
Recommendation for casuarinin flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

corylus heterophylla terminalia arjuna bark

Synonyms

neo vescalin, 11-de(6-carboxy-2,3,4-trihydroxyphenyl)-, cyclic 16,18-(4,4',5,5',6,6'-hexahydroxy(1,1-biphenyl)-2,2'-dicarboxylate) 17-(3,4,5-trihydroxybenzoate), (15beta)- PubMed: Variability in Foliar Ellagitannins of Hippophaë rhamnoides L. and Identification of a New Ellagitannin, Hippophaenin C. PubMed: Protective effect of casuarinin against glutamate-induced apoptosis in HT22 cells through inhibition of oxidative stress-mediated MAPK phosphorylation. PubMed: Impact of extraction techniques on antioxidant capacities and phytochemical composition of polyphenol-rich extracts. PubMed: Differences in Metabolism of Ellagitannins by Human Gut Microbiota ex Vivo Cultures. PubMed: Flavonoids, gallotannins and ellagitannins in Syzygium guineense and the traditional use among Malian healers. PubMed: Hepatoprotective and antioxidant effect of ellagitannins and galloyl esters isolated from Melaleuca styphelioides on carbon tetrachloride-induced hepatotoxicity in HepG2 cells. PubMed: High-resolution bioactivity profiling combined with HPLC-HRMS-SPE-NMR: α-Glucosidase inhibitors and acetylated ellagic acid rhamnosides from Myrcia palustris DC. (Myrtaceae). PubMed: Determination of phenolic compounds and antioxidant activity in leaves from wild Rubus L. species. PubMed: Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus acutissima Cortex. PubMed: Extracts and compounds with anti-diabetic complications and anti-cancer activity from Castanea mollissina Blume (Chinese chestnut). PubMed: Hepatitis C virus inhibitory hydrolysable tannins from the fruits of Terminalia chebula. PubMed: Chemical constituents from Melastoma dodecandrum and their inhibitory activity on interleukin-8 production in HT-29 cells. PubMed: Anti-Candida targets and cytotoxicity of casuarinin isolated from Plinia cauliflora leaves in a bioactivity-guided study. PubMed: C-glucosidic ellagitannins from Lythri herba (European Pharmacopoeia): chromatographic profile and structure determination. PubMed: Inhibitory effect of tannins from galls of Carpinus tschonoskii on the degranulation of RBL-2H3 Cells. PubMed: Casuarinin suppresses TARC/CCL17 and MDC/CCL22 production via blockade of NF-κB and STAT1 activation in HaCaT cells. PubMed: Casuarinin suppresses TNF-α-induced ICAM-1 expression via blockade of NF-κB activation in HaCaT cells. PubMed: Fatty acid synthase inhibitors from Geum japonicum Thunb. var. chinense. PubMed: Active compounds from Lagerstroemia speciosa, insulin-like glucose uptake-stimulatory/inhibitory and adipocyte differentiation-inhibitory activities in 3T3-L1 cells. PubMed: Anticancer and antioxidant tannins from Pimenta dioica leaves. PubMed: Casuarinin from the bark of Terminalia arjuna induces apoptosis and cell cycle arrest in human breast adenocarcinoma MCF-7 cells. PubMed: Induction of cell cycle arrest and apoptosis in human non-small cell lung cancer A549 cells by casuarinin from the bark of Terminalia arjuna Linn. PubMed: Casuarinin protects cultured MDCK cells from hydrogen peroxide-induced oxidative stress and DNA oxidative damage. PubMed: Determination of hydrolyzable tannins in the fruit of Terminalia chebula Retz. by high-performance liquid chromatography and capillary electrophoresis. PubMed: Antiherpes simplex virus type 2 activity of casuarinin from the bark of Terminalia arjuna Linn. PubMed: Identification of hydrolysable tannins in the reaction zone of Eucalyptus nitens wood by high performance liquid chromatography--electrospray ionisation mass spectrometry. PubMed: Induction of apoptosis by hydrolyzable tannins from Eugenia jambos L. on human leukemia cells. PubMed: Suppression of lipopolysaccharide-induced nuclear factor-kappaB activity by theaflavin-3,3'-digallate from black tea and other polyphenols through down-regulation of IkappaB kinase activity in macrophages. PubMed: Inhibitory effects of hydrolyzable tannins from Melastoma dodecandrum Lour. on nitric oxide production by a murine macrophage-like cell line, RAW264.7, activated with lipopolysaccharide and interferon-gamma. PubMed: Carbonic anhydrase inhibitors from the pericarps of Punica granatum L. PubMed: Antitumor agents, 129. Tannins and related compounds as selective cytotoxic agents. PubMed: In vitro screening of antimotility effect on human sperm with polyphenolic compounds purified from Chinese herbal medicines. PubMed: Tannins occurring in the toxic Brazilian plant Thiloa glaucocarpa.