gartanin
Identification
| Name | gartanin |
| CAS Number | 33390-42-0 |
| FDA UNII | Search |
| Molecular Formula | C23 H24 O6 |
| Molecular Weight | 396.43948000 |
| Nikkaji Number | J167.474I |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 9.787e-005 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for gartanin usage levels up to | not for fragrance use. |
| Recommendation for gartanin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
1,3,5,8-
tetrahydroxy-2,4-bis(3-methylbut-2-enyl)xanthen-9-one
9H-
xanthen-9-one, 1,3,5,8-tetrahydroxy-2,4-bis(3-methyl-2-butenyl)-
PubMed:
Mangostanaxanthone VIII, a new xanthone from Garcinia mangostana and its cytotoxic activity.
PubMed:
Mangostanaxanthone VII, a new cytotoxic xanthone from Garcinia mangostana.
PubMed:
Protective effects of compounds from Garcinia mangostana L. (mangosteen) against UVB damage in HaCaT cells and hairless mice.
PubMed:
Gartanin induces cell cycle arrest and autophagy and suppresses migration involving PI3K/Akt/mTOR and MAPK signalling pathway in human glioma cells.
PubMed:
Gartanin Protects Neurons against Glutamate-Induced Cell Death in HT22 Cells: Independence of Nrf-2 but Involvement of HO-1 and AMPK.
PubMed:
Natural Xanthones from Garcinia mangostana with Multifunctional Activities for the Therapy of Alzheimer's Disease.
PubMed:
Gartanin, an isoprenylated xanthone from the mangosteen fruit (Garcinia mangostana), is an androgen receptor degradation enhancer.
PubMed:
In vitro antiproliferative activity of uncommon xanthones from branches of Garcinia achachairu.
PubMed:
Gartanin induces autophagy through JNK activation which extenuates caspase-dependent apoptosis.
PubMed:
Metabolite footprinting of Plasmodium falciparum following exposure to Garcinia mangostana Linn. crude extract.
PubMed:
Cytotoxic prenylated xanthones from the pericarps of Garcinia mangostana.
PubMed:
The effect of gartanin, a naturally occurring xanthone in mangosteen juice, on the mTOR pathway, autophagy, apoptosis, and the growth of human urinary bladder cancer cell lines.
PubMed:
Antifibrotic constituents from Garcinia mangostana.
PubMed:
Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen).
PubMed:
Activity of mangosteen xanthones and teleocidin a-2 in death receptor expression enhancement and tumor necrosis factor related apoptosis-inducing ligand assays.
PubMed:
Medicinal properties of mangosteen (Garcinia mangostana).
PubMed:
Garcinia mangostana: a source of potential anti-cancer lead compounds against CEM-SS cell line.
PubMed:
HPLC analysis of selected xanthones in mangosteen fruit.
PubMed:
Quantitative and qualitative determination of six xanthones in Garcinia mangostana L. by LC-PDA and LC-ESI-MS.
PubMed:
Antioxidant xanthones from the pericarp of Garcinia mangostana (Mangosteen).
PubMed:
Cytotoxic prenylated xanthones from the young fruit of Garcinia mangostana.