gardenin B
Identification
| Name | gardenin B |
| CAS Number | 2798-20-1 |
| FDA UNII | 313E89KN5E |
| Molecular Formula | C19 H18 O7 |
| Molecular Weight | 358.34686000 |
| Nikkaji Number | J94.492K |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 11.46 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for gardenin B usage levels up to | not for fragrance use. |
| Recommendation for gardenin B flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
4H-1-
benzopyran-4-one, 5-hydroxy-6,7,8-trimethoxy-2-(4-methoxyphenyl)-
5-
hydroxy-6,7,8-trimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
5-
hydroxy-6,7,8-trimethoxy-2-(4-methoxyphenyl)chromen-4-one
PubMed:
Characterization of bioactive constituents from the gum resin of Gardenia lucida and its pharmacological potential.
PubMed:
Gardenin B-induced cell death in human leukemia cells involves multiple caspases but is independent of the generation of reactive oxygen species.
PubMed:
Simultaneous Quantification of Five Bioactive Flavonoids in High Altitude Plant Actinocarya tibetica by LC-ESI-MS/MS.
PubMed:
Identification of a unique 2-oxoglutarate-dependent flavone 7-O-demethylase completes the elucidation of the lipophilic flavone network in basil.
PubMed:
5-demethyltangeretin inhibits human nonsmall cell lung cancer cell growth by inducing G2/M cell cycle arrest and apoptosis.
PubMed:
Effect of a labile methyl donor on the transformation of 5-demethyltangeretin and the related implication on bioactivity.
PubMed:
Characterization of two candidate flavone 8-O-methyltransferases suggests the existence of two potential routes to nevadensin in sweet basil.
PubMed:
Biological activity of secondary metabolites from Peltostigma guatemalense.
PubMed:
Distribution of 8-oxygenated leaf-surface flavones in the genus Ocimum.
PubMed:
A distinctive flavonoid chemistry for the anomalous genus Biebersteinia.