bilobetin
Identification
| Name | bilobetin |
| CAS Number | 521-32-4 |
| FDA UNII | Search |
| Molecular Formula | C31 H20 O10 |
| Molecular Weight | 552.49240000 |
| Nikkaji Number | J92.484I |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 0.008998 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for bilobetin usage levels up to | not for fragrance use. |
| Recommendation for bilobetin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
3''',8-
biflavone, 4',5,5'',7,7''-pentahydroxy-4'''-methoxy-
8-[5-(5,7-
dihydroxy-4-oxochromen-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
4'-mono
methylamentoflavone
PubMed:
[Chemical constituents from leaves of Garcinia xanthochymus].
PubMed:
Rapid Screening and Structural Characterization of Antioxidants from the Extract of Selaginella doederleinii Hieron with DPPH-UPLC-Q-TOF/MS Method.
PubMed:
Virtual screening of natural inhibitors to the predicted HBx protein structure of Hepatitis B Virus using molecular docking for identification of potential lead molecules for liver cancer.
PubMed:
UPLC-PDA-TOF/MS coupled with multivariate statistical analysis to rapidly analyze and evaluate Ginkgo biloba leaves from different origin.
PubMed:
Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.
PubMed:
Antiviral activity-guided fractionation from Araucaria angustifolia leaves extract.
PubMed:
How to realize the linear scale-up process for rapid purification using high-performance counter-current chromatography.
PubMed:
In vitro peroxynitrite scavenging activity of 6-hydroxykynurenic acid and other flavonoids from Gingko biloba yellow leaves.
PubMed:
Osteoblast differentiation stimulating activity of biflavonoids from Cephalotaxus koreana.
PubMed:
Inhibition of cGMP-phosphodiesterase-5 by biflavones of Ginkgo biloba.
PubMed:
Biflavones from Chamaecyparis obtusa.
PubMed:
Flavonoids from Metasequoia glyptostroboides.
PubMed:
Constituents of antibacterial extract of Caesalpinia paraguariensis Burk.
PubMed:
Antifungal activity of biflavones from Taxus baccata and Ginkgo biloba.
PubMed:
Biflavones of Ginkgo biloba stimulate lipolysis in 3T3-L1 adipocytes.
PubMed:
Effects of prenylated flavonoids and biflavonoids on lipopolysaccharide-induced nitric oxide production from the mouse macrophage cell line RAW 264.7.
PubMed:
The effects of two new antagonists of secretory PLA2 on TNF, iNOS, and COX-2 expression in activated macrophages.
PubMed:
Inhibition of cAMP-phosphodiesterase by biflavones of Ginkgo biloba in rat adipose tissue.
PubMed:
[HPLC determination of six flavonoid constituents in Ginkgo biloba leaves].
PubMed:
Cytotoxic biflavonoids from Selaginella willdenowii.
PubMed:
Suppression of mouse lymphocyte proliferation in vitro by naturally-occurring biflavonoids.
PubMed:
Effects of some compounds isolated fromCelaenodendron mexicanum standl (euphorbiaceae) on seeds and phytopathogenic fungi.
PubMed:
Seasonal Variations of the Flavonoid Content from Ginkgo biloba Leaves.
PubMed:
HPLC Separation and Quantitative Determination of Biflavones in Leaves from Ginkgo biloba.