americanin A

CAS: 69506-79-2 C18 H16 O6 MW: 328.32072000

Identification

Nameamericanin A
CAS Number69506-79-2
FDA UNIISearch
Molecular FormulaC18 H16 O6
Molecular Weight328.32072000
Nikkaji NumberJ1.090.840J

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 5447 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for americanin A usage levels up tonot for fragrance use.
Recommendation for americanin A flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

phytolacca americana

Synonyms

(E)-3-[(2S,3S)-2-(3,4- dihydroxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]prop-2-enal PubMed: Suppression of melanin synthesis by Americanin A in melan-a cells via regulation of microphthalmia-associated transcription factor. PubMed: Antitumor Activity of Americanin A Isolated from the Seeds of Phytolacca americana by Regulating the ATM/ATR Signaling Pathway and the Skp2-p27 Axis in Human Colon Cancer Cells. PubMed: Chemical composition of the endocarps of fruits of Styrax officinalis L. PubMed: Matrix metalloproteinase-1 inhibitory activities of Morinda citrifolia seed extract and its constituents in UVA-irradiated human dermal fibroblasts. PubMed: Inhibitory effects of Morinda citrifolia extract and its constituents on melanogenesis in murine B16 melanoma cells. PubMed: Inhibitory effects of constituents of Morinda citrifolia seeds on elastase and tyrosinase. PubMed: Identification of novel orosensory active molecules in cured vanilla Beans (Vanilla planifolia). PubMed: Lignans and anthraquinones from the fruits of Morinda citrifolia. PubMed: Americanin, a bioactive dibenzylbutyrolactone lignan, from the seeds of Centaurea americana. PubMed: Chemical constituents of the fruits of Morinda citrifolia (Noni) and their antioxidant activity. PubMed: Chemical constituents of Morinda citrifolia fruits inhibit copper-induced low-density lipoprotein oxidation. PubMed: Sesquineolignans and other constituents from the seeds of Joannesia princeps. PubMed: Isolation and characterization of americanin, a specific inhibitor of thrombin, from the salivary glands of the lone star tick Amblyomma americanum (L.). PubMed: Structures of americanol A and isoamericanol A having a neurotrophic property from the seeds of Phytolacca americana. PubMed: Total synthesis of neolignans, americanin A and isoamericanin A.