obtusilactone A
Identification
| Name | obtusilactone A |
| CAS Number | 56522-15-7 |
| FDA UNII | Search |
| Molecular Formula | C19 H32 O3 |
| Molecular Weight | 308.46164000 |
| Nikkaji Number | J12.712D |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 1.091 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for obtusilactone A usage levels up to | not for fragrance use. |
| Recommendation for obtusilactone A flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
(S)-4,5-
dihydro-4-hydroxy-5-methylene-3-((Z)-tetradecan-1-ylidene)furan-2(3H)-one
2(3H)-
furanone, dihydro-4-hydroxy-5-methylene-3-tetradecylidene-, (3Z,4S)-
(3Z,4S)-4-
hydroxy-5-methylidene-3-tetradecylideneoxolan-2-one
PubMed:
Enhancement of Bone Marrow-Derived Mesenchymal Stem Cell Osteogenesis and New Bone Formation in Rats by Obtusilactone A.
PubMed:
Evaluation of the genotoxic activity of ethanol extract and secondary metabolites isolated from Aiouea trinervis Meisn. (Lauraceae).
PubMed:
Obtusilactone A and (-)-sesamin induce apoptosis in human lung cancer cells by inhibiting mitochondrial Lon protease and activating DNA damage checkpoints.
PubMed:
Antioxidants from the leaves of Cinnamomum kotoense.
PubMed:
Isolation of new esters from the stems of Cinnamomum reticulatum Hay.
PubMed:
Cytotoxic and genotoxic butanolides and lignans from Aiouea trinervis.
PubMed:
Biologically active gamma-lactones and methylketoalkenes from Lindera benzoin.