calendic acid
Identification
| Name | calendic acid |
| CAS Number | 28872-28-8 |
| FDA UNII | Search |
| Molecular Formula | C18 H30 O2 |
| Molecular Weight | 278.43550000 |
| XlogP3 | 6.70 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 0.02371 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for calendic acid usage levels up to | not for fragrance use. |
| Recommendation for calendic acid flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
(8E,10E,12Z)-
octadeca-8,10,12-trienoic acid
PubMed:
Robust inhibitory effects of conjugated linolenic acids on a cyclooxygenase-related linoleate 10S-dioxygenase: Comparison with COX-1 and COX-2.
PubMed:
Induction of apoptosis and inhibition of invasion in choriocarcinoma JEG-3 cells by α-calendic acid and β-calendic acid.
PubMed:
Fatty acid composition of lipids in pot marigold (Calendula officinalis L.) seed genotypes.
PubMed:
Growth inhibition and apoptosis induction by all-trans-conjugated linolenic acids on human colon cancer cells.
PubMed:
Conjugated fatty acids accumulate to high levels in phospholipids of metabolically engineered soybean and Arabidopsis seeds.
PubMed:
Lipids as renewable resources: current state of chemical and biotechnological conversion and diversification.
PubMed:
Effect of conjugated FA on feed intake, body composition, and liver FA in mice.
PubMed:
Mechanism of 1,4-dehydrogenation catalyzed by a fatty acid (1,4)-desaturase of Calendula officinalis.
PubMed:
Identification and analysis of a gene from Calendula officinalis encoding a fatty acid conjugase.
PubMed:
Formation of conjugated delta8,delta10-double bonds by delta12-oleic-acid desaturase-related enzymes: biosynthetic origin of calendic acid.
PubMed:
Isolation and characterization of a calendic acid producing (8,11)-linoleoyl desaturase.
PubMed:
Calendic acid in seed oils of the genus Calendula.