sciadonic acid

CAS: 7019-85-4 C20 H34 O2 MW: 306.48938000

Identification

Namesciadonic acid
CAS Number7019-85-4
FDA UNII69Y3H52QB5
Molecular FormulaC20 H34 O2
Molecular Weight306.48938000

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 0.002364 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for sciadonic acid usage levels up tonot for fragrance use.
Recommendation for sciadonic acid flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

ginkgo biloba pinus sylvestris

Synonyms

(5Z,11Z,14Z)- 5,11,14- eicosatrienoic acid 11,14- eicosatrienoic acid, (Z,Z,Z)- (5Z,11Z,14Z)- icosa-5,11,14-trienoic acid PubMed: The Hypotriglyceridemic Effect of Sciadonic Acid is Mediated by the Inhibition of Δ9-Desaturase Expression and Activity. PubMed: Phospholipid Incorporation of Non-Methylene-Interrupted Fatty Acids (NMIFA) in Murine Microglial BV-2 Cells Reduces Pro-Inflammatory Mediator Production. PubMed: Isolation of two Δ5 polymethylene interrupted fatty acids from Podocarpus falcatus by countercurrent chromatography. PubMed: Metabolic conversion of C20 polymethylene-interrupted polyunsaturated fatty acids to essential fatty acids. PubMed: Incorporation of sciadonic acid into cellular phospholipids reduces pro-inflammatory mediators in murine macrophages through NF-κB and MAPK signaling pathways. PubMed: Sciadonic acid modulates prostaglandin E2 production by epithelial cells during infection with C. albicans and C. dubliniensis. PubMed: Eicosadienoic acid differentially modulates production of pro-inflammatory modulators in murine macrophages. PubMed: Effects of non-methylene-interrupted polyunsaturated fatty acid, sciadonic (all-cis-5,11,14-eicosatrienoic acid) on lipid metabolism in rats. PubMed: Inhibitory effect of juniperonic acid (Delta-5c,11c,14c,17c-20:4, omega-3) on bombesin-induced proliferation of Swiss 3T3 cells. PubMed: Metabolic pathway that produces essential fatty acids from polymethylene-interrupted polyunsaturated fatty acids in animal cells. PubMed: Cloning and characterization of unusual fatty acid desaturases from Anemone leveillei: identification of an acyl-coenzyme A C20 Delta5-desaturase responsible for the synthesis of sciadonic acid. PubMed: Effects of Japanese Torreya (Torreya nucifera) seed oil on the activities and mRNA expression of lipid metabolism-related enzymes in rats. PubMed: Effects of Japanese torreya (Torreya nucifera) seed oil on lipid metabolism in rats. PubMed: Production and protein kinase C activation of diacylglycerols containing polymethylene-interrupted PUFA. PubMed: Metabolic characterization of sciadonic acid (5c,11c,14c-eicosatrienoic acid) as an effective substitute for arachidonate of phosphatidylinositol. PubMed: Occurrence of a novel cannabimimetic molecule 2-sciadonoylglycerol (2-eicosa-5',11',14'-trienoylglycerol) in the umbrella pine Sciadopitys verticillata seeds.