4-nerolidyl catechol

CAS: 74683-11-7 C21 H30 O2 MW: 314.46850000

Identification

Name4-nerolidyl catechol
CAS Number74683-11-7
FDA UNIISearch
Molecular FormulaC21 H30 O2
Molecular Weight314.46850000
Nikkaji NumberJ911.662A

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 0.007014 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for 4-nerolidyl catechol usage levels up tonot for fragrance use.
Recommendation for 4-nerolidyl catechol flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

pothomorphe peltata pothomorphe umbellata

Synonyms

1,2- benzenediol, 4-(1-ethenyl-1,5,9-trimethyl-4,8-decadienyl)- 4- nerolidylcatechol 4-[(6E)-3,7,11- trimethyldodeca-1,6,10-trien-3-yl]benzene-1,2-diol PubMed: 4-Nerolidylcatechol: apoptosis by mitochondrial mechanisms with reduction in cyclin D1 at G0/G1 stage of the chronic myelogenous K562 cell line. PubMed: Liposomal Entrapment of 4-Nerolidylcatechol: Impact on Phospholipid Dynamics, Drug Stability and Bioactivity. PubMed: 4-Nerolidylcatechol analogues as promising anticancer agents. PubMed: In vivo antimalarial activity and mechanisms of action of 4-nerolidylcatechol derivatives. PubMed: Anticancer and Anti-Inflammatory Activities of a Standardized Dichloromethane Extract from Piper umbellatum L. Leaves. PubMed: Antioxidant effect of 4-nerolidylcatechol and α-tocopherol in erythrocyte ghost membranes and phospholipid bilayers. PubMed: Evaluation of antimicrobial and antimalarial activities of crude extract, fractions and 4-nerolidylcathecol from the aerial parts of Piper umbellata L. (Piperaceae). PubMed: Pothomorphe umbellata: antifungal activity against strains of Trichophyton rubrum. PubMed: Antioxidant and cytotoxic effects of crude extract, fractions and 4-nerolidylcathecol from aerial parts of Pothomorphe umbellata L. (Piperaceae). PubMed: 4-Nerolidylcatechol and its synthetic analogues: antioxidant activity and toxicity evaluation. PubMed: Anti-inflammatory and antinociceptive activities of LQFM002 - A 4-nerolidylcatechol derivative. PubMed: Stability and antioxidant activity of semi-synthetic derivatives of 4-nerolidylcatechol. PubMed: Anti-inflammatory effect of (E)-4-(3,7-dimethylocta-2,6-dienylamino)phenol, a new derivative of 4-nerolidylcatechol. PubMed: Proteasome inhibition and ROS generation by 4-nerolidylcatechol induces melanoma cell death. PubMed: Impact of ultrasound-assisted extraction on quality and photostability of the Pothomorphe umbellata extracts. PubMed: In vivo and in vitro antimalarial activity of 4-nerolidylcatechol. PubMed: Piper peltatum: biomass and 4-nerolidylcatechol production. PubMed: New antimalarial and cytotoxic 4-nerolidylcatechol derivatives. PubMed: Apoptosis induction by 4-nerolidylcatechol in melanoma cell lines. PubMed: Bioactive aristolactams from Piper umbellatum. PubMed: Dose-dependent in vitro inhibition of rabbit corneal matrix metalloproteinases by an extract of Pothomorphe umbellata after alkali injury. PubMed: Protective effects of 4-nerolidylcatechol against genotoxicity induced by cyclophosphamide. PubMed: In vitro inhibition of Plasmodium falciparum by substances isolated from Amazonian antimalarial plants. PubMed: In vitro and in vivo inhibition of skin matrix metalloproteinases by Pothomorphe umbellata root extract. PubMed: Chemical stability and SPF determination of Pothomorphe umbellata extract gel and photostability of 4-nerolidylcathecol. PubMed: Inhibitory effects of Piper umbellatum and Piper peltatum extracts towards myotoxic phospholipases A2 from Bothrops snake venoms: isolation of 4-nerolidylcatechol as active principle. PubMed: Evaluation of percutaneous absorption of 4-nerolidylcathecol from four topical formulations. PubMed: Investigation of the larvicidal activity of Pothomorphe peltata and isolation of the active constituent. PubMed: Cytotoxic 4-nerolidylcatechol from Pothomorphe peltata inhibits topoisomerase I activity. PubMed: 4-Nerolidylcatechol from Pothomorphe spp. scavenges peroxyl radicals and inhibits Fe(II)-dependent DNA damage.