cyclocurcumin
Identification
| Name | cyclocurcumin |
| CAS Number | 153127-42-5 |
| FDA UNII | Search |
| Molecular Formula | C21 H20 O6 |
| Molecular Weight | 368.38560000 |
| Nikkaji Number | J2.978.889H |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 51.35 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for cyclocurcumin usage levels up to | not for fragrance use. |
| Recommendation for cyclocurcumin flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
2-(4-
hydroxy-3-methoxyphenyl)-6-[(E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-2,3-dihydropyran-4-one
PubMed:
Inhibitory effects of curcumin and cyclocurcumin in 1-methyl-4-phenylpyridinium (MPP
) induced neurotoxicity in differentiated PC12 cells.
PubMed:
Cyclocurcumin, a curcumin derivative, exhibits immune-modulating ability and is a potential compound for the treatment of rheumatoid arthritis as predicted by the MM-PBSA method.
PubMed:
Cyclocurcumin, an Antivasoconstrictive Constituent of Curcuma longa (Turmeric).
PubMed:
Investigating the Neuroprotective Effects of Turmeric Extract: Structural Interactions of β-Amyloid Peptide with Single Curcuminoids.
PubMed:
The Effectiveness of Natural Diarylheptanoids against Trypanosoma cruzi: Cytotoxicity, Ultrastructural Alterations and Molecular Modeling Studies.
PubMed:
Molecular docking studies of curcumin natural derivatives with DNA topoisomerase I and II-DNA complexes.
PubMed:
Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric.
PubMed:
Human papilloma virus 16 E6 protein as a target for curcuminoids, curcumin conjugates and congeners for chemoprevention of oral and cervical cancers.
PubMed:
Photoinduced trans-to-cis isomerization of cyclocurcumin.
PubMed:
Inhibitory effect of curcuminoids on MCF-7 cell proliferation and structure-activity relationships.
PubMed:
Nematocidal activity of turmeric: synergistic action of curcuminoids.