garcinone E
Identification
| Name | garcinone E |
| CAS Number | 112649-21-5 |
| FDA UNII | Search |
| Molecular Formula | C28 H32 O6 |
| Molecular Weight | 464.55824000 |
| Nikkaji Number | J776.823K |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 1.651e-006 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for garcinone E usage levels up to | not for fragrance use. |
| Recommendation for garcinone E flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
2,3,6,8-
tetrahydroxy-1,4,7-tris(3-methylbut-2-enyl)xanthen-9-one
PubMed:
Garcixanthone A, a new cytotoxic xanthone from the pericarps of Garcinia mangostana.
PubMed:
Garcinone E induces apoptosis and inhibits migration and invasion in ovarian cancer cells.
PubMed:
New xanthones and cytotoxic constituents from Garcinia mangostana fruit hulls against human hepatocellular, breast, and colorectal cancer cell lines.
PubMed:
Mangostanaxanthones III and IV: advanced glycation end-product inhibitors from the pericarp of Garcinia mangostana.
PubMed:
Xanthones Isolated from the Pericarp of Mangosteen Inhibit Neurotransmitter Receptors Expressed in Xenopus Oocytes.
PubMed:
Antifibrotic constituents from Garcinia mangostana.
PubMed:
A new prenylated xanthone from Garcinia xipshuanbannaensis Y.H. Li.
PubMed:
Antiplasmodial constituents from the fruit pericarp of Pentadesma butyracea.
PubMed:
Xanthone constituents of the fruits of Garcinia mangostana with anticomplement activity.
PubMed:
Medicinal properties of mangosteen (Garcinia mangostana).
PubMed:
Xanthones from the botanical dietary supplement mangosteen (Garcinia mangostana) with aromatase inhibitory activity.
PubMed:
Antioxidant xanthones from the pericarp of Garcinia mangostana (Mangosteen).
PubMed:
A geranylated biphenyl derivative from Garcinia malvgostana.
PubMed:
Garcinone E, a xanthone derivative, has potent cytotoxic effect against hepatocellular carcinoma cell lines.