(±)-aegeline

CAS: 456-12-2 C18 H19 N O3 MW: 297.35403000

Identification

Name(±)-aegeline
CAS Number456-12-2
FDA UNII60T59LN3SG
Molecular FormulaC18 H19 N O3
Molecular Weight297.35403000
MDL NumberMFCD00048045

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 235.3 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for (±)-aegeline usage levels up tonot for fragrance use.
Recommendation for (±)-aegeline flavor usage levels up tonot for flavor use.

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

TCI AMERICA

Moving Your Chemistry Forward

We continuously strive to advance our technology.

View All Website 1-800-423-8616 Sales-US@TCIchemicals.com;

Potential Uses

None Found

Natural Occurrence

aegle marmelos leaf

Synonyms

N-(2- hydroxy-2(4-methoxyphenyl)ethyl)-3-phenyl-2-propenamide, (E)- (E)-N-[2- hydroxy-2-(4-methoxyphenyl)ethyl]-3-phenylprop-2-enamide 2- propenamide, N-(2-hydroxy-2-(4-methoxyphenyl)ethyl)-3-phenyl-, (E)- PubMed: Pharmacokinetics and Tissue Distribution of Aegeline after Oral Administration in Mice PubMed: Overview of regulation of dietary supplements in the USA and issues of adulteration with phenethylamines (PEAs) PubMed: Aegeline from Aegle marmelos stimulates glucose transport via Akt and Rac1 signaling, and contributes to a cytoskeletal rearrangement through PI3K/Rac1 PubMed: Aegeline, a natural product from the plant Aegle marmelos, mimics the yeast SNARE protein Sec22p in suppressing à-synuclein and Bax toxicity in yeast PubMed: Aegeline inspired synthesis of novel amino alcohol and thiazolidinedione hybrids with antiadipogenic activity in 3T3-L1 cells PubMed: Simultaneous Determination of Aegeline and Six Coumarins from Different Parts of the Plant Aegle marmelos Using UHPLC-PDA-MS and Chiral Separation of Aegeline Enantiomers Using HPLC-ToF-MS PubMed: Aegeline inspired synthesis of novel ?3-AR agonist improves insulin sensitivity in vitro and in vivo models of insulin resistance PubMed: LOX-1, the Common Therapeutic Target in Hypercholesterolemia: A New Perspective of Antiatherosclerotic Action of Aegeline PubMed: Corrigendum to "Aegeline, a natural product from the plant Aegle marmelos, mimics the yeast SNARE protein Sec22p in suppressing à-synuclein and Bax toxicity in yeast" [Bioorg. Med. Chem. Lett. 29 (2019) 454-460] PubMed: Effects of aegeline, a main alkaloid of Aegle Marmelos Correa leaves, on the histamine release from mast cells PubMed: Inhibition of CYP3A4 and CYP1A2 by Aegle marmelos and its constituents PubMed: Lipid lowering agents of natural origin: An account of some promising chemotypes PubMed: Antihyperglycemic and antidyslipidemic agent from Aegle marmelos PubMed: Interaction of active compounds from Aegle marmelos CORREA with histamine-1 receptor PubMed: The Role of Adverse Event Reporting in the FDA Response to a Multistate Outbreak of Liver Disease Associated with a Dietary Supplement PubMed: Two new cytotoxic furoquinoline alkaloids isolated from Aegle marmelos (Linn.) Correa PubMed: Synthesis of novel N-(2-hydroxy-2-p-tolylethyl)-amide and N-(2-oxo-2-p-tolylethyl)-amide derivatives and their antidyslipidemic and antioxidant activity PubMed: Synthesis of new N-acryl-1-amino-2-phenylethanol and N-acyl-1-amino-3-aryloxypropanols and evaluation of their antihyperlipidemic, LDL-oxidation and antioxidant activity PubMed: Anti adipogenic activity of Aegle marmelos Correa PubMed: Biological Evaluation of Aegle marmelos Fruit Extract and Isolated Aegeline in Alleviating Pain-Depression Dyad: In Silico Analysis of Aegeline on MAO-A and iNOS PubMed: ACTION OF RANEY NICKEL ON AEGELINE, AEGELONE AND DIHYDROAEGELINE PubMed: Outbreak of severe hepatitis linked to weight-loss supplement OxyELITE Pro PubMed: Hydrosoluble formazan XTT: its application to natural products drug discovery for Leishmania PubMed: Severe Acute Hepatocellular Injury Attributed to OxyELITE Pro: A Case Series PubMed: Binolam-AlCl: a two-centre catalyst for the synthesis of enantioenriched cyanohydrin O-phosphates